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Items: 1 to 20 of 97

1.

Telocinobufagin inhibits the epithelial-mesenchymal transition of breast cancer cells through the phosphoinositide 3-kinase/protein kinase B/extracellular signal-regulated kinase/Snail signaling pathway.

Gao Y, Shi L, Cao Z, Zhu X, Li F, Wang R, Xu J, Zhong J, Zhang B, Lu S.

Oncol Lett. 2018 May;15(5):7837-7845. doi: 10.3892/ol.2018.8349. Epub 2018 Mar 26.

2.

Activation of NF-κB by the RANKL/RANK system up-regulates snail and twist expressions and induces epithelial-to-mesenchymal transition in mammary tumor cell lines.

Tsubaki M, Komai M, Fujimoto S, Itoh T, Imano M, Sakamoto K, Shimaoka H, Takeda T, Ogawa N, Mashimo K, Fujiwara D, Mukai J, Sakaguchi K, Satou T, Nishida S.

J Exp Clin Cancer Res. 2013 Sep 5;32:62. doi: 10.1186/1756-9966-32-62.

3.

Oxymatrine reverses epithelial-mesenchymal transition in breast cancer cells by depressing αβ3 integrin/FAK/PI3K/Akt signaling activation.

Chen Y, Chen L, Zhang JY, Chen ZY, Liu TT, Zhang YY, Fu LY, Fan SQ, Zhang MQ, Gan SQ, Zhang NL, Shen XC.

Onco Targets Ther. 2019 Aug 8;12:6253-6265. doi: 10.2147/OTT.S209056. eCollection 2019.

4.
5.

Snail regulated by PKC/GSK-3β pathway is crucial for EGF-induced epithelial-mesenchymal transition (EMT) of cancer cells.

Liu ZC, Chen XH, Song HX, Wang HS, Zhang G, Wang H, Chen DY, Fang R, Liu H, Cai SH, Du J.

Cell Tissue Res. 2014 Nov;358(2):491-502. doi: 10.1007/s00441-014-1953-2. Epub 2014 Aug 16.

PMID:
25124796
6.

Angiotensin II type 2 receptor-interacting protein 3a inhibits ovarian carcinoma metastasis via the extracellular HMGA2-mediated ERK/EMT pathway.

Ping H, Guo L, Xi J, Wang D.

Tumour Biol. 2017 Jun;39(6):1010428317713389. doi: 10.1177/1010428317713389.

PMID:
28651497
7.

Snail promotes cell migration through PI3K/AKT-dependent Rac1 activation as well as PI3K/AKT-independent pathways during prostate cancer progression.

Henderson V, Smith B, Burton LJ, Randle D, Morris M, Odero-Marah VA.

Cell Adh Migr. 2015;9(4):255-64. doi: 10.1080/19336918.2015.1013383. Epub 2015 Jul 24.

8.

EGF induces epithelial-mesenchymal transition through phospho-Smad2/3-Snail signaling pathway in breast cancer cells.

Kim J, Kong J, Chang H, Kim H, Kim A.

Oncotarget. 2016 Dec 20;7(51):85021-85032. doi: 10.18632/oncotarget.13116.

9.

3,5,4'-Trimethoxystilbene, a natural methoxylated analog of resveratrol, inhibits breast cancer cell invasiveness by downregulation of PI3K/Akt and Wnt/β-catenin signaling cascades and reversal of epithelial-mesenchymal transition.

Tsai JH, Hsu LS, Lin CL, Hong HM, Pan MH, Way TD, Chen WJ.

Toxicol Appl Pharmacol. 2013 Nov 1;272(3):746-56. doi: 10.1016/j.taap.2013.07.019. Epub 2013 Aug 3.

PMID:
23921149
10.

The pan-inhibitor of Aurora kinases danusertib induces apoptosis and autophagy and suppresses epithelial-to-mesenchymal transition in human breast cancer cells.

Li JP, Yang YX, Liu QL, Zhou ZW, Pan ST, He ZX, Zhang X, Yang T, Pan SY, Duan W, He SM, Chen XW, Qiu JX, Zhou SF.

Drug Des Devel Ther. 2015 Feb 17;9:1027-62. doi: 10.2147/DDDT.S74412. eCollection 2015.

11.

Stabilization of Snail through AKT/GSK-3β signaling pathway is required for TNF-α-induced epithelial-mesenchymal transition in prostate cancer PC3 cells.

Wang H, Fang R, Wang XF, Zhang F, Chen DY, Zhou B, Wang HS, Cai SH, Du J.

Eur J Pharmacol. 2013 Aug 15;714(1-3):48-55. doi: 10.1016/j.ejphar.2013.05.046. Epub 2013 Jun 11.

PMID:
23769744
12.

HRG-β1-driven ErbB3 signaling induces epithelial-mesenchymal transition in breast cancer cells.

Kim J, Jeong H, Lee Y, Kim C, Kim H, Kim A.

BMC Cancer. 2013 Aug 12;13:383. doi: 10.1186/1471-2407-13-383.

13.

Activation of IL-8 via PI3K/Akt-dependent pathway is involved in leptin-mediated epithelial-mesenchymal transition in human breast cancer cells.

Wang L, Tang C, Cao H, Li K, Pang X, Zhong L, Dang W, Tang H, Huang Y, Wei L, Su M, Chen T.

Cancer Biol Ther. 2015;16(8):1220-30. doi: 10.1080/15384047.2015.1056409. Epub 2015 Jun 29.

14.

Quercetin reverses EGF-induced epithelial to mesenchymal transition and invasiveness in prostate cancer (PC-3) cell line via EGFR/PI3K/Akt pathway.

Bhat FA, Sharmila G, Balakrishnan S, Arunkumar R, Elumalai P, Suganya S, Raja Singh P, Srinivasan N, Arunakaran J.

J Nutr Biochem. 2014 Nov;25(11):1132-1139. doi: 10.1016/j.jnutbio.2014.06.008. Epub 2014 Aug 1.

PMID:
25150162
15.

AKT/GSK-3β regulates stability and transcription of snail which is crucial for bFGF-induced epithelial-mesenchymal transition of prostate cancer cells.

Liu ZC, Wang HS, Zhang G, Liu H, Chen XH, Zhang F, Chen DY, Cai SH, Du J.

Biochim Biophys Acta. 2014 Oct;1840(10):3096-105. doi: 10.1016/j.bbagen.2014.07.018. Epub 2014 Aug 1.

PMID:
25088797
16.

Involvement of Pin1 induction in epithelial-mesenchymal transition of tamoxifen-resistant breast cancer cells.

Kim MR, Choi HK, Cho KB, Kim HS, Kang KW.

Cancer Sci. 2009 Oct;100(10):1834-41. doi: 10.1111/j.1349-7006.2009.01260.x. Epub 2009 Jul 24.

17.

LYTAK1 attenuates proliferation of retinal pigment epithelial cells through TGF-β-mediated epithelial-mesenchymal transition via the ERK/AKT signaling pathway.

Chen Z, Ni N, Mei Y, Yang Z.

Exp Ther Med. 2017 Nov;14(5):4951-4957. doi: 10.3892/etm.2017.5187. Epub 2017 Sep 22.

18.

Propolin C Inhibited Migration and Invasion via Suppression of EGFR-Mediated Epithelial-to-Mesenchymal Transition in Human Lung Cancer Cells.

Pai JT, Lee YC, Chen SY, Leu YL, Weng MS.

Evid Based Complement Alternat Med. 2018 Feb 25;2018:7202548. doi: 10.1155/2018/7202548. eCollection 2018.

19.
20.

Ginkgolic Acid Inhibits Invasion and Migration and TGF-β-Induced EMT of Lung Cancer Cells Through PI3K/Akt/mTOR Inactivation.

Baek SH, Ko JH, Lee JH, Kim C, Lee H, Nam D, Lee J, Lee SG, Yang WM, Um JY, Sethi G, Ahn KS.

J Cell Physiol. 2017 Feb;232(2):346-354. doi: 10.1002/jcp.25426. Epub 2016 Jun 2.

PMID:
27177359

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