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Items: 1 to 20 of 97

1.

Detection of Cyclooxygenase-2-Derived Oxygenation Products of the Endogenous Cannabinoid 2-Arachidonoylglycerol in Mouse Brain.

Morgan AJ, Kingsley PJ, Mitchener MM, Altemus M, Patrick TA, Gaulden AD, Marnett LJ, Patel S.

ACS Chem Neurosci. 2018 Jul 18;9(7):1552-1559. doi: 10.1021/acschemneuro.7b00499. Epub 2018 May 9.

2.

13-Methylarachidonic acid is a positive allosteric modulator of endocannabinoid oxygenation by cyclooxygenase.

Kudalkar SN, Nikas SP, Kingsley PJ, Xu S, Galligan JJ, Rouzer CA, Banerjee S, Ji L, Eno MR, Makriyannis A, Marnett LJ.

J Biol Chem. 2015 Mar 20;290(12):7897-909. doi: 10.1074/jbc.M114.634014. Epub 2015 Feb 2.

3.

Oxygenation of the endocannabinoid, 2-arachidonylglycerol, to glyceryl prostaglandins by cyclooxygenase-2.

Kozak KR, Rowlinson SW, Marnett LJ.

J Biol Chem. 2000 Oct 27;275(43):33744-9.

4.

Competition and allostery govern substrate selectivity of cyclooxygenase-2.

Mitchener MM, Hermanson DJ, Shockley EM, Brown HA, Lindsley CW, Reese J, Rouzer CA, Lopez CF, Marnett LJ.

Proc Natl Acad Sci U S A. 2015 Oct 6;112(40):12366-71. doi: 10.1073/pnas.1507307112. Epub 2015 Sep 21. Erratum in: Proc Natl Acad Sci U S A. 2016 Mar 8;113(10):E1413.

5.

Glycerylprostaglandin synthesis by resident peritoneal macrophages in response to a zymosan stimulus.

Rouzer CA, Marnett LJ.

J Biol Chem. 2005 Jul 22;280(29):26690-700. Epub 2005 May 25.

6.

Assay of Endocannabinoid Oxidation by Cyclooxygenase-2.

Kudalkar SN, Kingsley PJ, Marnett LJ.

Methods Mol Biol. 2016;1412:205-15. doi: 10.1007/978-1-4939-3539-0_21.

7.

Substrate-selective COX-2 inhibition as a novel strategy for therapeutic endocannabinoid augmentation.

Hermanson DJ, Gamble-George JC, Marnett LJ, Patel S.

Trends Pharmacol Sci. 2014 Jul;35(7):358-67. doi: 10.1016/j.tips.2014.04.006. Epub 2014 May 18. Review.

8.

Prostaglandin H synthase-2-catalyzed oxygenation of 2-arachidonoylglycerol is more sensitive to peroxide tone than oxygenation of arachidonic acid.

Musee J, Marnett LJ.

J Biol Chem. 2012 Oct 26;287(44):37383-94. doi: 10.1074/jbc.M112.381202. Epub 2012 Sep 1.

9.

Hydrolysis of prostaglandin glycerol esters by the endocannabinoid-hydrolyzing enzymes, monoacylglycerol lipase and fatty acid amide hydrolase.

Vila A, Rosengarth A, Piomelli D, Cravatt B, Marnett LJ.

Biochemistry. 2007 Aug 21;46(33):9578-85. Epub 2007 Jul 25.

10.

Inhibition of COX-2 expression by endocannabinoid 2-arachidonoylglycerol is mediated via PPAR-γ.

Du H, Chen X, Zhang J, Chen C.

Br J Pharmacol. 2011 Aug;163(7):1533-49. doi: 10.1111/j.1476-5381.2011.01444.x.

11.

Implication of the anti-inflammatory bioactive lipid prostaglandin D2-glycerol ester in the control of macrophage activation and inflammation by ABHD6.

Alhouayek M, Masquelier J, Cani PD, Lambert DM, Muccioli GG.

Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):17558-63. doi: 10.1073/pnas.1314017110. Epub 2013 Oct 7.

12.

WWL70 attenuates PGE2 production derived from 2-arachidonoylglycerol in microglia by ABHD6-independent mechanism.

Tanaka M, Moran S, Wen J, Affram K, Chen T, Symes AJ, Zhang Y.

J Neuroinflammation. 2017 Jan 10;14(1):7. doi: 10.1186/s12974-016-0783-4.

13.

The pharmacology and therapeutic relevance of endocannabinoid derived cyclo-oxygenase (COX)-2 products.

Woodward DF, Carling RW, Cornell CL, Fliri HG, Martos JL, Pettit SN, Liang Y, Wang JW.

Pharmacol Ther. 2008 Oct;120(1):71-80. doi: 10.1016/j.pharmthera.2008.08.001. Epub 2008 Aug 6. Review.

PMID:
18700152
14.

Amino acid determinants in cyclooxygenase-2 oxygenation of the endocannabinoid 2-arachidonylglycerol.

Kozak KR, Prusakiewicz JJ, Rowlinson SW, Schneider C, Marnett LJ.

J Biol Chem. 2001 Aug 10;276(32):30072-7. Epub 2001 Jun 11.

15.

Non-redundant functions of cyclooxygenases: oxygenation of endocannabinoids.

Rouzer CA, Marnett LJ.

J Biol Chem. 2008 Mar 28;283(13):8065-9. doi: 10.1074/jbc.R800005200. Epub 2008 Feb 4. Review.

17.

Inactivation of lipid glyceryl ester metabolism in human THP1 monocytes/macrophages by activated organophosphorus insecticides: role of carboxylesterases 1 and 2.

Xie S, Borazjani A, Hatfield MJ, Edwards CC, Potter PM, Ross MK.

Chem Res Toxicol. 2010 Dec 20;23(12):1890-904. doi: 10.1021/tx1002194.

18.

Endocannabinoids and their oxygenation by cyclo-oxygenases, lipoxygenases and other oxygenases.

Urquhart P, Nicolaou A, Woodward DF.

Biochim Biophys Acta. 2015 Apr;1851(4):366-76. doi: 10.1016/j.bbalip.2014.12.015. Epub 2014 Dec 24. Review.

PMID:
25543004
19.

COX-2 oxidative metabolite of endocannabinoid 2-AG enhances excitatory glutamatergic synaptic transmission and induces neurotoxicity.

Sang N, Zhang J, Chen C.

J Neurochem. 2007 Sep;102(6):1966-1977. doi: 10.1111/j.1471-4159.2007.04668.x. Epub 2007 Jun 1.

20.

Multiple Forms of Endocannabinoid and Endovanilloid Signaling Regulate the Tonic Control of GABA Release.

Lee SH, Ledri M, Tóth B, Marchionni I, Henstridge CM, Dudok B, Kenesei K, Barna L, Szabó SI, Renkecz T, Oberoi M, Watanabe M, Limoli CL, Horvai G, Soltesz I, Katona I.

J Neurosci. 2015 Jul 8;35(27):10039-57. doi: 10.1523/JNEUROSCI.4112-14.2015.

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