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Selective dopamine D3 receptor antagonism significantly attenuates stress-induced immobility in a rat model of post-traumatic stress disorder.

Rice OV, Ashby CR Jr, Dixon C, Laurenzo W, Hayden J, Song R, Li J, Tiwari AK, Gardner EL.

Synapse. 2018 Aug;72(8):e22035. doi: 10.1002/syn.22035. Epub 2018 Jun 7.


Role of dopamine D3 receptor in alleviating behavioural deficits in animal models of post-traumatic stress disorder.

Song D, Ge Y, Chen Z, Shang C, Guo Y, Zhao T, Li Y, Wu N, Song R, Li J.

Prog Neuropsychopharmacol Biol Psychiatry. 2018 Jun 8;84(Pt A):190-200. doi: 10.1016/j.pnpbp.2018.03.001. Epub 2018 Mar 3.


YQA14: a novel dopamine D3 receptor antagonist that inhibits cocaine self-administration in rats and mice, but not in D3 receptor-knockout mice.

Song R, Yang RF, Wu N, Su RB, Li J, Peng XQ, Li X, Gaál J, Xi ZX, Gardner EL.

Addict Biol. 2012 Mar;17(2):259-73. doi: 10.1111/j.1369-1600.2011.00317.x. Epub 2011 Apr 20.


The selective dopamine D3 receptor antagonists SB-277011A and NGB 2904 and the putative partial D3 receptor agonist BP-897 attenuate methamphetamine-enhanced brain stimulation reward in rats.

Spiller K, Xi ZX, Peng XQ, Newman AH, Ashby CR Jr, Heidbreder C, Gaál J, Gardner EL.

Psychopharmacology (Berl). 2008 Mar;196(4):533-42. Epub 2007 Nov 6.


Effects of the selective dopamine D3 receptor antagonist SB-277011A on the reinforcing effects of nicotine as measured by a progressive-ratio schedule in rats.

Ross JT, Corrigall WA, Heidbreder CA, LeSage MG.

Eur J Pharmacol. 2007 Mar 22;559(2-3):173-9. Epub 2007 Jan 19.


A modified single-prolonged stress model for post-traumatic stress disorder.

Wang W, Liu Y, Zheng H, Wang HN, Jin X, Chen YC, Zheng LN, Luo XX, Tan QR.

Neurosci Lett. 2008 Aug 22;441(2):237-41. doi: 10.1016/j.neulet.2008.06.031. Epub 2008 Jun 18.


Inhibiting corticosterone synthesis during fear memory formation exacerbates cued fear extinction memory deficits within the single prolonged stress model.

Keller SM, Schreiber WB, Stanfield BR, Knox D.

Behav Brain Res. 2015;287:182-6. doi: 10.1016/j.bbr.2015.03.043. Epub 2015 Mar 31.


Role of dopamine D3 receptors in the expression of conditioned fear in rats.

Swain SN, Beuk J, Heidbreder CA, Beninger RJ.

Eur J Pharmacol. 2008 Jan 28;579(1-3):167-76. Epub 2007 Oct 13.


Effect of paroxetine on enhanced contextual fear induced by single prolonged stress in rats.

Takahashi T, Morinobu S, Iwamoto Y, Yamawaki S.

Psychopharmacology (Berl). 2006 Dec;189(2):165-73. Epub 2006 Oct 10.


The selective D₃ receptor antagonist SB-277011A attenuates morphine-triggered reactivation of expression of cocaine-induced conditioned place preference.

Rice OV, Heidbreder CA, Gardner EL, Schonhar CD, Ashby CR Jr.

Synapse. 2013 Aug;67(8):469-75. doi: 10.1002/syn.21653. Epub 2013 Mar 25.


The selective dopamine D3 receptor antagonist SB-277011A reduces nicotine-enhanced brain reward and nicotine-paired environmental cue functions.

Pak AC, Ashby CR Jr, Heidbreder CA, Pilla M, Gilbert J, Xi ZX, Gardner EL.

Int J Neuropsychopharmacol. 2006 Oct;9(5):585-602. Epub 2006 Aug 31.


Activation of Sigma-1 receptor ameliorates anxiety-like behavior and cognitive impairments in a rat model of post-traumatic stress disorder.

Ji LL, Peng JB, Fu CH, Cao D, Li D, Tong L, Wang ZY.

Behav Brain Res. 2016 Sep 15;311:408-415. doi: 10.1016/j.bbr.2016.05.056. Epub 2016 Jun 6.


Traumatic stress causes distinctive effects on fear circuit catecholamines and the fear extinction profile in a rodent model of posttraumatic stress disorder.

Lin CC, Tung CS, Lin PH, Huang CL, Liu YP.

Eur Neuropsychopharmacol. 2016 Sep;26(9):1484-1495. doi: 10.1016/j.euroneuro.2016.06.004. Epub 2016 Aug 2.


The effects of two highly selective dopamine D3 receptor antagonists (SB-277011A and NGB-2904) on food self-administration in a rodent model of obesity.

Thanos PK, Michaelides M, Ho CW, Wang GJ, Newman AH, Heidbreder CA, Ashby CR Jr, Gardner EL, Volkow ND.

Pharmacol Biochem Behav. 2008 Jun;89(4):499-507. doi: 10.1016/j.pbb.2008.02.003. Epub 2008 Feb 8.


Dopamine D(3) receptor antagonist SB-277011A inhibits methamphetamine self-administration and methamphetamine-induced reinstatement of drug-seeking in rats.

Higley AE, Kiefer SW, Li X, Gaál J, Xi ZX, Gardner EL.

Eur J Pharmacol. 2011 Jun 1;659(2-3):187-92. doi: 10.1016/j.ejphar.2011.02.046. Epub 2011 Apr 3.


Importance of early environment in the development of post-traumatic stress disorder-like behaviors.

Imanaka A, Morinobu S, Toki S, Yamawaki S.

Behav Brain Res. 2006 Oct 2;173(1):129-37. Epub 2006 Jul 24.


Systemic administrations of β-estradiol alleviate both conditioned and sensitized fear responses in an ovariectomized rat model of post-traumatic stress disorder.

Mirshekar M, Abrari K, Goudarzi I, Rashidy-Pour A.

Neurobiol Learn Mem. 2013 May;102:12-9. doi: 10.1016/j.nlm.2013.02.003. Epub 2013 Mar 6.


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