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Items: 1 to 20 of 94

1.

Can targeting ANGPTL proteins improve glucose tolerance?

Davies BSJ.

Diabetologia. 2018 Jun;61(6):1277-1281. doi: 10.1007/s00125-018-4604-4. Epub 2018 Apr 4.

PMID:
29619530
2.

On the mechanism of angiopoietin-like protein 8 for control of lipoprotein lipase activity.

Kovrov O, Kristensen KK, Larsson E, Ploug M, Olivecrona G.

J Lipid Res. 2019 Jan 27. pii: jlr.M088807. doi: 10.1194/jlr.M088807. [Epub ahead of print]

3.

Increased plasma and adipose tissue levels of ANGPTL8/Betatrophin and ANGPTL4 in people with hypertension.

Abu-Farha M, Cherian P, Qaddoumi MG, AlKhairi I, Sriraman D, Alanbaei M, Abubaker J.

Lipids Health Dis. 2018 Mar 1;17(1):35. doi: 10.1186/s12944-018-0681-0.

4.

Angiopoietin-like 3 in lipoprotein metabolism.

Kersten S.

Nat Rev Endocrinol. 2017 Dec;13(12):731-739. doi: 10.1038/nrendo.2017.119. Epub 2017 Oct 6. Review.

PMID:
28984319
5.

Angiopoietin-like protein 3 (ANGPTL3) deficiency and familial combined hypolipidemia.

Tarugi P, Bertolini S, Calandra S.

J Biomed Res. 2018 Apr 12. doi: 10.7555/JBR.32.20170114. [Epub ahead of print]

6.

Atypical angiopoietin-like protein that regulates ANGPTL3.

Quagliarini F, Wang Y, Kozlitina J, Grishin NV, Hyde R, Boerwinkle E, Valenzuela DM, Murphy AJ, Cohen JC, Hobbs HH.

Proc Natl Acad Sci U S A. 2012 Nov 27;109(48):19751-6. doi: 10.1073/pnas.1217552109. Epub 2012 Nov 12.

7.

Increased ANGPTL3, 4 and ANGPTL8/betatrophin expression levels in obesity and T2D.

Abu-Farha M, Al-Khairi I, Cherian P, Chandy B, Sriraman D, Alhubail A, Al-Refaei F, AlTerki A, Abubaker J.

Lipids Health Dis. 2016 Oct 13;15(1):181.

8.

Genetics and regulation of angiopoietin-like proteins 3 and 4.

Li C.

Curr Opin Lipidol. 2006 Apr;17(2):152-6. Review.

PMID:
16531751
9.

Angiopoietin-like proteins 3, 4 and 8: regulating lipid metabolism and providing new hope for metabolic syndrome.

Li Y, Teng C.

J Drug Target. 2014 Sep;22(8):679-87. doi: 10.3109/1061186X.2014.928715. Epub 2014 Jun 24. Review.

PMID:
24960069
10.

Angiopoietin-like protein 3 and 4 expression 4 and their serum levels in hepatocellular carcinoma.

El-Shal AS, Zidan HE, Rashad NM, Wadea FM.

Cytokine. 2017 Aug;96:75-86. doi: 10.1016/j.cyto.2017.03.006. Epub 2017 Mar 31.

PMID:
28371666
11.

Absence of ANGPTL4 in adipose tissue improves glucose tolerance and attenuates atherogenesis.

Aryal B, Singh AK, Zhang X, Varela L, Rotllan N, Goedeke L, Chaube B, Camporez JP, Vatner DF, Horvath TL, Shulman GI, Suárez Y, Fernández-Hernando C.

JCI Insight. 2018 Mar 22;3(6). pii: 97918. doi: 10.1172/jci.insight.97918. [Epub ahead of print]

12.

Differential association of plasma angiopoietin-like proteins 3 and 4 with lipid and metabolic traits.

Mehta N, Qamar A, Qu L, Qasim AN, Mehta NN, Reilly MP, Rader DJ.

Arterioscler Thromb Vasc Biol. 2014 May;34(5):1057-63. doi: 10.1161/ATVBAHA.113.302802. Epub 2014 Mar 13.

13.

Regulation of lipid metabolism by angiopoietin-like proteins.

Dijk W, Kersten S.

Curr Opin Lipidol. 2016 Jun;27(3):249-56. doi: 10.1097/MOL.0000000000000290. Review.

PMID:
27023631
14.

Mice lacking ANGPTL8 (Betatrophin) manifest disrupted triglyceride metabolism without impaired glucose homeostasis.

Wang Y, Quagliarini F, Gusarova V, Gromada J, Valenzuela DM, Cohen JC, Hobbs HH.

Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):16109-14. doi: 10.1073/pnas.1315292110. Epub 2013 Sep 16.

15.

Transgenic angiopoietin-like (angptl)4 overexpression and targeted disruption of angptl4 and angptl3: regulation of triglyceride metabolism.

Köster A, Chao YB, Mosior M, Ford A, Gonzalez-DeWhitt PA, Hale JE, Li D, Qiu Y, Fraser CC, Yang DD, Heuer JG, Jaskunas SR, Eacho P.

Endocrinology. 2005 Nov;146(11):4943-50. Epub 2005 Aug 4.

PMID:
16081640
16.
17.

Angptl3 deficiency is associated with increased insulin sensitivity, lipoprotein lipase activity, and decreased serum free fatty acids.

Robciuc MR, Maranghi M, Lahikainen A, Rader D, Bensadoun A, Öörni K, Metso J, Minicocci I, Ciociola E, Ceci F, Montali A, Arca M, Ehnholm C, Jauhiainen M.

Arterioscler Thromb Vasc Biol. 2013 Jul;33(7):1706-13. doi: 10.1161/ATVBAHA.113.301397. Epub 2013 May 9. Erratum in: Arterioscler Thromb Vasc Biol. 2013 Jul;33(7):e124. Oörni, Katariina [corrected to Öörni, Katariina].

PMID:
23661675
18.

ANGPTL3 Inhibitors - Their Role in Cardiovascular Disease Through Regulation of Lipid Metabolism.

Geladari E, Tsamadia P, Vallianou NG.

Circ J. 2019 Jan 25;83(2):267-273. doi: 10.1253/circj.CJ-18-0442. Epub 2018 Nov 30.

19.

A highly conserved motif within the NH2-terminal coiled-coil domain of angiopoietin-like protein 4 confers its inhibitory effects on lipoprotein lipase by disrupting the enzyme dimerization.

Yau MH, Wang Y, Lam KS, Zhang J, Wu D, Xu A.

J Biol Chem. 2009 May 1;284(18):11942-52. doi: 10.1074/jbc.M809802200. Epub 2009 Feb 26.

20.

GPIHBP1 stabilizes lipoprotein lipase and prevents its inhibition by angiopoietin-like 3 and angiopoietin-like 4.

Sonnenburg WK, Yu D, Lee EC, Xiong W, Gololobov G, Key B, Gay J, Wilganowski N, Hu Y, Zhao S, Schneider M, Ding ZM, Zambrowicz BP, Landes G, Powell DR, Desai U.

J Lipid Res. 2009 Dec;50(12):2421-9. doi: 10.1194/jlr.M900145-JLR200. Epub 2009 Jun 21.

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