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Items: 1 to 20 of 95

1.

Developmental History Provides a Roadmap for the Emergence of Tumor Plasticity.

Tata PR, Chow RD, Saladi SV, Tata A, Konkimalla A, Bara A, Montoro D, Hariri LP, Shih AR, Mino-Kenudson M, Mou H, Kimura S, Ellisen LW, Rajagopal J.

Dev Cell. 2018 Mar 26;44(6):679-693.e5. doi: 10.1016/j.devcel.2018.02.024.

2.

The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment.

Mollaoglu G, Jones A, Wait SJ, Mukhopadhyay A, Jeong S, Arya R, Camolotto SA, Mosbruger TL, Stubben CJ, Conley CJ, Bhutkar A, Vahrenkamp JM, Berrett KC, Cessna MH, Lane TE, Witt BL, Salama ME, Gertz J, Jones KB, Snyder EL, Oliver TG.

Immunity. 2018 Oct 16;49(4):764-779.e9. doi: 10.1016/j.immuni.2018.09.020.

3.

FoxA1 and FoxA2 drive gastric differentiation and suppress squamous identity in NKX2-1-negative lung cancer.

Camolotto SA, Pattabiraman S, Mosbruger TL, Jones A, Belova VK, Orstad G, Streiff M, Salmond L, Stubben C, Kaestner KH, Snyder EL.

Elife. 2018 Nov 26;7. pii: e38579. doi: 10.7554/eLife.38579.

4.

SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas.

Bass AJ, Watanabe H, Mermel CH, Yu S, Perner S, Verhaak RG, Kim SY, Wardwell L, Tamayo P, Gat-Viks I, Ramos AH, Woo MS, Weir BA, Getz G, Beroukhim R, O'Kelly M, Dutt A, Rozenblatt-Rosen O, Dziunycz P, Komisarof J, Chirieac LR, Lafargue CJ, Scheble V, Wilbertz T, Ma C, Rao S, Nakagawa H, Stairs DB, Lin L, Giordano TJ, Wagner P, Minna JD, Gazdar AF, Zhu CQ, Brose MS, Cecconello I, Ribeiro U Jr, Marie SK, Dahl O, Shivdasani RA, Tsao MS, Rubin MA, Wong KK, Regev A, Hahn WC, Beer DG, Rustgi AK, Meyerson M.

Nat Genet. 2009 Nov;41(11):1238-42. doi: 10.1038/ng.465. Epub 2009 Oct 4.

5.

Sex determining region Y-Box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lung.

Yuan P, Kadara H, Behrens C, Tang X, Woods D, Solis LM, Huang J, Spinola M, Dong W, Yin G, Fujimoto J, Kim E, Xie Y, Girard L, Moran C, Hong WK, Minna JD, Wistuba II.

PLoS One. 2010 Feb 9;5(2):e9112. doi: 10.1371/journal.pone.0009112.

6.

KRAS and NKX2-1 Mutations in Invasive Mucinous Adenocarcinoma of the Lung.

Hwang DH, Sholl LM, Rojas-Rudilla V, Hall DL, Shivdasani P, Garcia EP, MacConaill LE, Vivero M, Hornick JL, Kuo FC, Lindeman NI, Dong F.

J Thorac Oncol. 2016 Apr;11(4):496-503. doi: 10.1016/j.jtho.2016.01.010. Epub 2016 Jan 30.

7.

Thyroid Progenitors Are Robustly Derived from Embryonic Stem Cells through Transient, Developmental Stage-Specific Overexpression of Nkx2-1.

Dame K, Cincotta S, Lang AH, Sanghrajka RM, Zhang L, Choi J, Kwok L, Wilson T, Kańduła MM, Monti S, Hollenberg AN, Mehta P, Kotton DN, Ikonomou L.

Stem Cell Reports. 2017 Feb 14;8(2):216-225. doi: 10.1016/j.stemcr.2016.12.024. Epub 2017 Feb 2.

8.

SOX2 promotes tumor growth of esophageal squamous cell carcinoma through the AKT/mammalian target of rapamycin complex 1 signaling pathway.

Gen Y, Yasui K, Nishikawa T, Yoshikawa T.

Cancer Sci. 2013 Jul;104(7):810-6. doi: 10.1111/cas.12155. Epub 2013 Apr 16.

9.

SOX2 gene amplification and protein overexpression are associated with better outcome in squamous cell lung cancer.

Wilbertz T, Wagner P, Petersen K, Stiedl AC, Scheble VJ, Maier S, Reischl M, Mikut R, Altorki NK, Moch H, Fend F, Staebler A, Bass AJ, Meyerson M, Rubin MA, Soltermann A, Lengerke C, Perner S.

Mod Pathol. 2011 Jul;24(7):944-53. doi: 10.1038/modpathol.2011.49. Epub 2011 Apr 1.

10.

Downregulation of a putative tumor suppressor BMP4 by SOX2 promotes growth of lung squamous cell carcinoma.

Fang WT, Fan CC, Li SM, Jang TH, Lin HP, Shih NY, Chen CH, Wang TY, Huang SF, Lee AY, Liu YL, Tsai FY, Huang CT, Yang SJ, Yen LJ, Chuu CP, Chen CY, Hsiung CA, Chang JY, Wang LH, Chang IS, Jiang SS.

Int J Cancer. 2014 Aug 15;135(4):809-19. doi: 10.1002/ijc.28734. Epub 2014 Jan 30.

11.

SOX2 Is the Determining Oncogenic Switch in Promoting Lung Squamous Cell Carcinoma from Different Cells of Origin.

Ferone G, Song JY, Sutherland KD, Bhaskaran R, Monkhorst K, Lambooij JP, Proost N, Gargiulo G, Berns A.

Cancer Cell. 2016 Oct 10;30(4):519-532. doi: 10.1016/j.ccell.2016.09.001.

12.

Morphologic and clinicopathologic features of lung squamous cell carcinomas expressing Sox2.

Brcic L, Sherer CK, Shuai Y, Hornick JL, Chirieac LR, Dacic S.

Am J Clin Pathol. 2012 Nov;138(5):712-8. doi: 10.1309/AJCP05TTWQTWNLTN.

PMID:
23086772
13.

Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm.

Que J, Okubo T, Goldenring JR, Nam KT, Kurotani R, Morrisey EE, Taranova O, Pevny LH, Hogan BL.

Development. 2007 Jul;134(13):2521-31. Epub 2007 May 23.

14.

Homeobox Transcription Factor NKX2-1 Promotes Cyclin D1 Transcription in Lung Adenocarcinomas.

Harada M, Sakai S, Ohhata T, Kitagawa K, Mikamo M, Nishimoto K, Uchida C, Niida H, Kotake Y, Sugimura H, Suda T, Kitagawa M.

Mol Cancer Res. 2017 Oct;15(10):1388-1397. doi: 10.1158/1541-7786.MCR-17-0114. Epub 2017 Jun 20.

15.
16.

Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung.

Maeda Y, Tsuchiya T, Hao H, Tompkins DH, Xu Y, Mucenski ML, Du L, Keiser AR, Fukazawa T, Naomoto Y, Nagayasu T, Whitsett JA.

J Clin Invest. 2012 Dec;122(12):4388-400. doi: 10.1172/JCI64048. Epub 2012 Nov 12.

17.

Sex-Determining Region Y-box 2 Promotes Growth of Lung Squamous Cell Carcinoma and Directly Targets Cyclin D1.

Li C, He B, Huang C, Yang H, Cao L, Huang J, Hu C.

DNA Cell Biol. 2017 Apr;36(4):264-272. doi: 10.1089/dna.2016.3562. Epub 2017 Feb 2.

PMID:
28151013
18.

[Expression of annexin I in different histological types of carcinomas].

Xue LY, Teng LH, Zou SM, Ren LQ, Zheng S, Luo W, Bi R, Lü N.

Zhonghua Zhong Liu Za Zhi. 2007 Jun;29(6):444-8. Chinese.

PMID:
17974280
19.

Predicting the molecular role of MEIS1 in esophageal squamous cell carcinoma.

Rad A, Farshchian M, Forghanifard MM, Matin MM, Bahrami AR, Geerts D, A'rabi A, Memar B, Abbaszadegan MR.

Tumour Biol. 2016 Feb;37(2):1715-25. doi: 10.1007/s13277-015-3780-9. Epub 2015 Aug 28.

PMID:
26314854
20.

Two novel splice variants of SOX2OT, SOX2OT-S1, and SOX2OT-S2 are coupregulated with SOX2 and OCT4 in esophageal squamous cell carcinoma.

Shahryari A, Rafiee MR, Fouani Y, Oliae NA, Samaei NM, Shafiee M, Semnani S, Vasei M, Mowla SJ.

Stem Cells. 2014 Jan;32(1):126-34. doi: 10.1002/stem.1542.

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