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Items: 1 to 20 of 82

1.

Loss of NF-κB1 Causes Gastric Cancer with Aberrant Inflammation and Expression of Immune Checkpoint Regulators in a STAT-1-Dependent Manner.

O'Reilly LA, Putoczki TL, Mielke LA, Low JT, Lin A, Preaudet A, Herold MJ, Yaprianto K, Tai L, Kueh A, Pacini G, Ferrero RL, Gugasyan R, Hu Y, Christie M, Wilcox S, Grumont R, Griffin MDW, O'Connor L, Smyth GK, Ernst M, Waring P, Gerondakis S, Strasser A.

Immunity. 2018 Mar 20;48(3):570-583.e8. doi: 10.1016/j.immuni.2018.03.003.

2.

Signaling mediated by the NF-κB sub-units NF-κB1, NF-κB2 and c-Rel differentially regulate Helicobacter felis-induced gastric carcinogenesis in C57BL/6 mice.

Burkitt MD, Williams JM, Duckworth CA, O'Hara A, Hanedi A, Varro A, Caamaño JH, Pritchard DM.

Oncogene. 2013 Dec 12;32(50):5563-73. doi: 10.1038/onc.2013.334. Epub 2013 Aug 26.

3.

miR-155-5p inhibition promotes the transition of bone marrow mesenchymal stem cells to gastric cancer tissue derived MSC-like cells via NF-κB p65 activation.

Zhu M, Wang M, Yang F, Tian Y, Cai J, Yang H, Fu H, Mao F, Zhu W, Qian H, Xu W.

Oncotarget. 2016 Mar 29;7(13):16567-80. doi: 10.18632/oncotarget.7767.

4.

BRAF activated non-coding RNA (BANCR) promoting gastric cancer cells proliferation via regulation of NF-κB1.

Zhang ZX, Liu ZQ, Jiang B, Lu XY, Ning XF, Yuan CT, Wang AL.

Biochem Biophys Res Commun. 2015 Sep 18;465(2):225-31. doi: 10.1016/j.bbrc.2015.07.158. Epub 2015 Aug 3.

PMID:
26248136
5.

Regulation of the transcription factor NF-kappaB1 by microRNA-9 in human gastric adenocarcinoma.

Wan HY, Guo LM, Liu T, Liu M, Li X, Tang H.

Mol Cancer. 2010 Jan 26;9:16. doi: 10.1186/1476-4598-9-16.

6.

IFN-γ-induced JAK/STAT, but not NF-κB, signaling pathway is insensitive to glucocorticoid in airway epithelial cells.

O'Connell D, Bouazza B, Kokalari B, Amrani Y, Khatib A, Ganther JD, Tliba O.

Am J Physiol Lung Cell Mol Physiol. 2015 Aug 15;309(4):L348-59. doi: 10.1152/ajplung.00099.2015. Epub 2015 Jun 19.

7.

NF-κB1, NF-κB2 and c-Rel differentially regulate susceptibility to colitis-associated adenoma development in C57BL/6 mice.

Burkitt MD, Hanedi AF, Duckworth CA, Williams JM, Tang JM, O'Reilly LA, Putoczki TL, Gerondakis S, Dimaline R, Caamano JH, Pritchard DM.

J Pathol. 2015 Jul;236(3):326-36. doi: 10.1002/path.4527. Epub 2015 Apr 21.

8.

Aurora kinase A promotes inflammation and tumorigenesis in mice and human gastric neoplasia.

Katsha A, Soutto M, Sehdev V, Peng D, Washington MK, Piazuelo MB, Tantawy MN, Manning HC, Lu P, Shyr Y, Ecsedy J, Belkhiri A, El-Rifai W.

Gastroenterology. 2013 Dec;145(6):1312-22.e1-8. doi: 10.1053/j.gastro.2013.08.050. Epub 2013 Aug 29.

9.

Hematopoietic NF-kappaB1 deficiency results in small atherosclerotic lesions with an inflammatory phenotype.

Kanters E, Gijbels MJ, van der Made I, Vergouwe MN, Heeringa P, Kraal G, Hofker MH, de Winther MP.

Blood. 2004 Feb 1;103(3):934-40. Epub 2003 Sep 25.

PMID:
14512319
10.

STAT1-deficient mice spontaneously develop estrogen receptor α-positive luminal mammary carcinomas.

Chan SR, Vermi W, Luo J, Lucini L, Rickert C, Fowler AM, Lonardi S, Arthur C, Young LJ, Levy DE, Welch MJ, Cardiff RD, Schreiber RD.

Breast Cancer Res. 2012 Jan 20;14(1):R16.

11.

miR-508-3p concordantly silences NFKB1 and RELA to inactivate canonical NF-κB signaling in gastric carcinogenesis.

Huang T, Kang W, Zhang B, Wu F, Dong Y, Tong JH, Yang W, Zhou Y, Zhang L, Cheng AS, Yu J, To KF.

Mol Cancer. 2016 Jan 22;15:9. doi: 10.1186/s12943-016-0493-7.

12.

Methylation-dependent activation of CDX1 through NF-κB: a link from inflammation to intestinal metaplasia in the human stomach.

Rau TT, Rogler A, Frischauf M, Jung A, Konturek PC, Dimmler A, Faller G, Sehnert B, El-Rifai W, Hartmann A, Voll RE, Schneider-Stock R.

Am J Pathol. 2012 Aug;181(2):487-98. doi: 10.1016/j.ajpath.2012.04.028. Epub 2012 Jun 27.

13.

TNF-α/TNFR1 signaling promotes gastric tumorigenesis through induction of Noxo1 and Gna14 in tumor cells.

Oshima H, Ishikawa T, Yoshida GJ, Naoi K, Maeda Y, Naka K, Ju X, Yamada Y, Minamoto T, Mukaida N, Saya H, Oshima M.

Oncogene. 2014 Jul 17;33(29):3820-9. doi: 10.1038/onc.2013.356. Epub 2013 Aug 26.

PMID:
23975421
14.

A20 inhibition of STAT1 expression in myeloid cells: a novel endogenous regulatory mechanism preventing development of enthesitis.

De Wilde K, Martens A, Lambrecht S, Jacques P, Drennan MB, Debusschere K, Govindarajan S, Coudenys J, Verheugen E, Windels F, Catrysse L, Lories R, McGonagle D, Beyaert R, van Loo G, Elewaut D.

Ann Rheum Dis. 2017 Mar;76(3):585-592. doi: 10.1136/annrheumdis-2016-209454. Epub 2016 Aug 22.

PMID:
27551052
15.

Loss of gastrokine-2 drives premalignant gastric inflammation and tumor progression.

Menheniott TR, O'Connor L, Chionh YT, Däbritz J, Scurr M, Rollo BN, Ng GZ, Jacobs S, Catubig A, Kurklu B, Mercer S, Minamoto T, Ong DE, Ferrero RL, Fox JG, Wang TC, Sutton P, Judd LM, Giraud AS.

J Clin Invest. 2016 Apr 1;126(4):1383-400. doi: 10.1172/JCI82655. Epub 2016 Mar 14.

16.

NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression.

Huber MA, Azoitei N, Baumann B, Grünert S, Sommer A, Pehamberger H, Kraut N, Beug H, Wirth T.

J Clin Invest. 2004 Aug;114(4):569-81.

17.

microRNA-146a inhibits G protein-coupled receptor-mediated activation of NF-κB by targeting CARD10 and COPS8 in gastric cancer.

Crone SG, Jacobsen A, Federspiel B, Bardram L, Krogh A, Lund AH, Friis-Hansen L.

Mol Cancer. 2012 Sep 20;11:71. doi: 10.1186/1476-4598-11-71.

18.

Macrophages promote progression of spasmolytic polypeptide-expressing metaplasia after acute loss of parietal cells.

Petersen CP, Weis VG, Nam KT, Sousa JF, Fingleton B, Goldenring JR.

Gastroenterology. 2014 Jun;146(7):1727-38.e8. doi: 10.1053/j.gastro.2014.02.007. Epub 2014 Feb 15.

19.

Conditional deletion of IkappaB-kinase-beta accelerates helicobacter-dependent gastric apoptosis, proliferation, and preneoplasia.

Shibata W, Takaishi S, Muthupalani S, Pritchard DM, Whary MT, Rogers AB, Fox JG, Betz KS, Kaestner KH, Karin M, Wang TC.

Gastroenterology. 2010 Mar;138(3):1022-34.e1-10. doi: 10.1053/j.gastro.2009.11.054. Epub 2009 Dec 4.

20.

Myeloid Differentiation Factor 88 Signaling in Bone Marrow-Derived Cells Promotes Gastric Tumorigenesis by Generation of Inflammatory Microenvironment.

Maeda Y, Echizen K, Oshima H, Yu L, Sakulsak N, Hirose O, Yamada Y, Taniguchi T, Jenkins BJ, Saya H, Oshima M.

Cancer Prev Res (Phila). 2016 Mar;9(3):253-63. doi: 10.1158/1940-6207.CAPR-15-0315. Epub 2016 Feb 17.

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