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Items: 1 to 20 of 111

1.

Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability.

Galanos P, Pappas G, Polyzos A, Kotsinas A, Svolaki I, Giakoumakis NN, Glytsou C, Pateras IS, Swain U, Souliotis VL, Georgakilas AG, Geacintov N, Scorrano L, Lukas C, Lukas J, Livneh Z, Lygerou Z, Chowdhury D, Sørensen CS, Bartek J, Gorgoulis VG.

Genome Biol. 2018 Mar 16;19(1):37. doi: 10.1186/s13059-018-1401-9.

2.

Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing.

Galanos P, Vougas K, Walter D, Polyzos A, Maya-Mendoza A, Haagensen EJ, Kokkalis A, Roumelioti FM, Gagos S, Tzetis M, Canovas B, Igea A, Ahuja AK, Zellweger R, Havaki S, Kanavakis E, Kletsas D, Roninson IB, Garbis SD, Lopes M, Nebreda A, Thanos D, Blow JJ, Townsend P, Sørensen CS, Bartek J, Gorgoulis VG.

Nat Cell Biol. 2016 Jul;18(7):777-89. doi: 10.1038/ncb3378. Epub 2016 Jun 20.

3.

Human somatic cells deficient for RAD52 are impaired for viral integration and compromised for most aspects of homology-directed repair.

Kan Y, Batada NN, Hendrickson EA.

DNA Repair (Amst). 2017 Jul;55:64-75. doi: 10.1016/j.dnarep.2017.04.006. Epub 2017 May 10.

4.

The xeroderma pigmentosum group E gene product DDB2 activates nucleotide excision repair by regulating the level of p21Waf1/Cip1.

Stoyanova T, Yoon T, Kopanja D, Mokyr MB, Raychaudhuri P.

Mol Cell Biol. 2008 Jan;28(1):177-87. Epub 2007 Oct 29.

5.
6.

Histone H3K56 acetylation, Rad52, and non-DNA repair factors control double-strand break repair choice with the sister chromatid.

Muñoz-Galván S, Jimeno S, Rothstein R, Aguilera A.

PLoS Genet. 2013;9(1):e1003237. doi: 10.1371/journal.pgen.1003237. Epub 2013 Jan 24.

7.

Analysis of p53 mutations and the expression of p53 and p21WAF1/CIP1 protein in 15 cases of sebaceous carcinoma of the eyelid.

Kiyosaki K, Nakada C, Hijiya N, Tsukamoto Y, Matsuura K, Nakatsuka K, Daa T, Yokoyama S, Imaizumi M, Moriyama M.

Invest Ophthalmol Vis Sci. 2010 Jan;51(1):7-11. doi: 10.1167/iovs.09-4127. Epub 2009 Jul 23.

PMID:
19628749
8.

Mammalian RAD52 Functions in Break-Induced Replication Repair of Collapsed DNA Replication Forks.

Sotiriou SK, Kamileri I, Lugli N, Evangelou K, Da-Ré C, Huber F, Padayachy L, Tardy S, Nicati NL, Barriot S, Ochs F, Lukas C, Lukas J, Gorgoulis VG, Scapozza L, Halazonetis TD.

Mol Cell. 2016 Dec 15;64(6):1127-1134. doi: 10.1016/j.molcel.2016.10.038.

9.

Clostridium difficile toxin A-induced colonocyte apoptosis involves p53-dependent p21(WAF1/CIP1) induction via p38 mitogen-activated protein kinase.

Kim H, Kokkotou E, Na X, Rhee SH, Moyer MP, Pothoulakis C, Lamont JT.

Gastroenterology. 2005 Dec;129(6):1875-88.

PMID:
16344056
10.

Conservative repair of a chromosomal double-strand break by single-strand DNA through two steps of annealing.

Storici F, Snipe JR, Chan GK, Gordenin DA, Resnick MA.

Mol Cell Biol. 2006 Oct;26(20):7645-57. Epub 2006 Aug 14.

11.

p53 and p21 regulate error-prone DNA repair to yield a lower mutation load.

Avkin S, Sevilya Z, Toube L, Geacintov N, Chaney SG, Oren M, Livneh Z.

Mol Cell. 2006 May 5;22(3):407-13.

12.

53BP1 fosters fidelity of homology-directed DNA repair.

Ochs F, Somyajit K, Altmeyer M, Rask MB, Lukas J, Lukas C.

Nat Struct Mol Biol. 2016 Aug;23(8):714-21. doi: 10.1038/nsmb.3251. Epub 2016 Jun 27.

PMID:
27348077
13.
14.

Yin Yang-1 inhibits vascular smooth muscle cell growth and intimal thickening by repressing p21WAF1/Cip1 transcription and p21WAF1/Cip1-Cdk4-cyclin D1 assembly.

Santiago FS, Ishii H, Shafi S, Khurana R, Kanellakis P, Bhindi R, Ramirez MJ, Bobik A, Martin JF, Chesterman CN, Zachary IC, Khachigian LM.

Circ Res. 2007 Jul 20;101(2):146-55. Epub 2007 Jun 7.

PMID:
17556661
15.

The gut-enriched Kruppel-like factor (Kruppel-like factor 4) mediates the transactivating effect of p53 on the p21WAF1/Cip1 promoter.

Zhang W, Geiman DE, Shields JM, Dang DT, Mahatan CS, Kaestner KH, Biggs JR, Kraft AS, Yang VW.

J Biol Chem. 2000 Jun 16;275(24):18391-8.

16.
17.

Cells from ERCC1-deficient mice show increased genome instability and a reduced frequency of S-phase-dependent illegitimate chromosome exchange but a normal frequency of homologous recombination.

Melton DW, Ketchen AM, Núñez F, Bonatti-Abbondandolo S, Abbondandolo A, Squires S, Johnson RT.

J Cell Sci. 1998 Feb;111 ( Pt 3):395-404.

18.

Visualization of recombination intermediates produced by RAD52-mediated single-strand annealing.

Van Dyck E, Stasiak AZ, Stasiak A, West SC.

EMBO Rep. 2001 Oct;2(10):905-9. Epub 2001 Sep 24.

19.

Transcriptional regulation during p21WAF1/CIP1-induced apoptosis in human ovarian cancer cells.

Wu Q, Kirschmeier P, Hockenberry T, Yang TY, Brassard DL, Wang L, McClanahan T, Black S, Rizzi G, Musco ML, Mirza A, Liu S.

J Biol Chem. 2002 Sep 27;277(39):36329-37. Epub 2002 Jul 22.

20.

The p53-p21WAF1 checkpoint pathway plays a protective role in preventing DNA rereplication induced by abrogation of FOXF1 function.

Lo PK, Lee JS, Sukumar S.

Cell Signal. 2012 Jan;24(1):316-24. doi: 10.1016/j.cellsig.2011.09.017. Epub 2011 Sep 22.

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