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Items: 1 to 20 of 105

1.

Gasdermin D Exerts Anti-inflammatory Effects by Promoting Neutrophil Death.

Kambara H, Liu F, Zhang X, Liu P, Bajrami B, Teng Y, Zhao L, Zhou S, Yu H, Zhou W, Silberstein LE, Cheng T, Han M, Xu Y, Luo HR.

Cell Rep. 2018 Mar 13;22(11):2924-2936. doi: 10.1016/j.celrep.2018.02.067.

2.

Noncanonical inflammasome signaling elicits gasdermin D-dependent neutrophil extracellular traps.

Chen KW, Monteleone M, Boucher D, Sollberger G, Ramnath D, Condon ND, von Pein JB, Broz P, Sweet MJ, Schroder K.

Sci Immunol. 2018 Aug 24;3(26). pii: eaar6676. doi: 10.1126/sciimmunol.aar6676.

PMID:
30143554
3.

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.

Shi J, Zhao Y, Wang K, Shi X, Wang Y, Huang H, Zhuang Y, Cai T, Wang F, Shao F.

Nature. 2015 Oct 29;526(7575):660-5. doi: 10.1038/nature15514. Epub 2015 Sep 16.

PMID:
26375003
4.

Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor.

Yang J, Liu Z, Wang C, Yang R, Rathkey JK, Pinkard OW, Shi W, Chen Y, Dubyak GR, Abbott DW, Xiao TS.

Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):6792-6797. doi: 10.1073/pnas.1800562115. Epub 2018 Jun 11.

5.

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion.

He WT, Wan H, Hu L, Chen P, Wang X, Huang Z, Yang ZH, Zhong CQ, Han J.

Cell Res. 2015 Dec;25(12):1285-98. doi: 10.1038/cr.2015.139. Epub 2015 Nov 27.

6.

Gasdermin D plays a vital role in the generation of neutrophil extracellular traps.

Sollberger G, Choidas A, Burn GL, Habenberger P, Di Lucrezia R, Kordes S, Menninger S, Eickhoff J, Nussbaumer P, Klebl B, Krüger R, Herzig A, Zychlinsky A.

Sci Immunol. 2018 Aug 24;3(26). pii: eaar6689. doi: 10.1126/sciimmunol.aar6689.

PMID:
30143555
7.

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores.

Liu X, Zhang Z, Ruan J, Pan Y, Magupalli VG, Wu H, Lieberman J.

Nature. 2016 Jul 7;535(7610):153-8. doi: 10.1038/nature18629.

8.

Cathepsin G Inhibition by Serpinb1 and Serpinb6 Prevents Programmed Necrosis in Neutrophils and Monocytes and Reduces GSDMD-Driven Inflammation.

Burgener SS, Leborgne NGF, Snipas SJ, Salvesen GS, Bird PI, Benarafa C.

Cell Rep. 2019 Jun 18;27(12):3646-3656.e5. doi: 10.1016/j.celrep.2019.05.065.

9.

Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis.

Kang R, Zeng L, Zhu S, Xie Y, Liu J, Wen Q, Cao L, Xie M, Ran Q, Kroemer G, Wang H, Billiar TR, Jiang J, Tang D.

Cell Host Microbe. 2018 Jul 11;24(1):97-108.e4. doi: 10.1016/j.chom.2018.05.009. Epub 2018 Jun 21.

10.

GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes.

Aglietti RA, Estevez A, Gupta A, Ramirez MG, Liu PS, Kayagaki N, Ciferri C, Dixit VM, Dueber EC.

Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7858-63. doi: 10.1073/pnas.1607769113. Epub 2016 Jun 23.

11.

Live-cell visualization of gasdermin D-driven pyroptotic cell death.

Rathkey JK, Benson BL, Chirieleison SM, Yang J, Xiao TS, Dubyak GR, Huang AY, Abbott DW.

J Biol Chem. 2017 Sep 1;292(35):14649-14658. doi: 10.1074/jbc.M117.797217. Epub 2017 Jul 18.

12.

Enterovirus 71 Inhibits Pyroptosis through Cleavage of Gasdermin D.

Lei X, Zhang Z, Xiao X, Qi J, He B, Wang J.

J Virol. 2017 Aug 24;91(18). pii: e01069-17. doi: 10.1128/JVI.01069-17. Print 2017 Sep 15.

13.

Mechanism and Regulation of Gasdermin-Mediated Cell Death.

Xia S, Hollingsworth LR 4th, Wu H.

Cold Spring Harb Perspect Biol. 2019 Aug 26. pii: a036400. doi: 10.1101/cshperspect.a036400. [Epub ahead of print]

PMID:
31451512
14.

Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death.

Orning P, Weng D, Starheim K, Ratner D, Best Z, Lee B, Brooks A, Xia S, Wu H, Kelliher MA, Berger SB, Gough PJ, Bertin J, Proulx MM, Goguen JD, Kayagaki N, Fitzgerald KA, Lien E.

Science. 2018 Nov 30;362(6418):1064-1069. doi: 10.1126/science.aau2818. Epub 2018 Oct 25.

15.

Guanylate-binding protein 5 licenses caspase-11 for Gasdermin-D mediated host resistance to Brucella abortus infection.

Cerqueira DM, Gomes MTR, Silva ALN, Rungue M, Assis NRG, Guimarães ES, Morais SB, Broz P, Zamboni DS, Oliveira SC.

PLoS Pathog. 2018 Dec 27;14(12):e1007519. doi: 10.1371/journal.ppat.1007519. eCollection 2018 Dec.

16.

The Inflammasome Drives GSDMD-Independent Secondary Pyroptosis and IL-1 Release in the Absence of Caspase-1 Protease Activity.

Schneider KS, Groß CJ, Dreier RF, Saller BS, Mishra R, Gorka O, Heilig R, Meunier E, Dick MS, Ćiković T, Sodenkamp J, Médard G, Naumann R, Ruland J, Kuster B, Broz P, Groß O.

Cell Rep. 2017 Dec 26;21(13):3846-3859. doi: 10.1016/j.celrep.2017.12.018.

17.

Gasdermin D plays a key role as a pyroptosis executor of non-alcoholic steatohepatitis in humans and mice.

Xu B, Jiang M, Chu Y, Wang W, Chen D, Li X, Zhang Z, Zhang D, Fan D, Nie Y, Shao F, Wu K, Liang J.

J Hepatol. 2018 Apr;68(4):773-782. doi: 10.1016/j.jhep.2017.11.040. Epub 2017 Dec 20.

PMID:
29273476
18.

Glycyrrhizin attenuates hepatic ischemia-reperfusion injury by suppressing HMGB1-dependent GSDMD-mediated kupffer cells pyroptosis.

Hua S, Ma M, Fei X, Zhang Y, Gong F, Fang M.

Int Immunopharmacol. 2019 Mar;68:145-155. doi: 10.1016/j.intimp.2019.01.002. Epub 2019 Jan 8.

PMID:
30634142
19.

Gasdermin D Protects from Melioidosis through Pyroptosis and Direct Killing of Bacteria.

Wang J, Deobald K, Re F.

J Immunol. 2019 Jun 15;202(12):3468-3473. doi: 10.4049/jimmunol.1900045. Epub 2019 Apr 29.

PMID:
31036765
20.

Structural Insight of Gasdermin Family Driving Pyroptotic Cell Death.

Ruan J.

Adv Exp Med Biol. 2019;1172:189-205. doi: 10.1007/978-981-13-9367-9_9. Review.

PMID:
31628657

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