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Items: 1 to 20 of 100

1.

Genetic Mechanisms of Immune Evasion in Colorectal Cancer.

Grasso CS, Giannakis M, Wells DK, Hamada T, Mu XJ, Quist M, Nowak JA, Nishihara R, Qian ZR, Inamura K, Morikawa T, Nosho K, Abril-Rodriguez G, Connolly C, Escuin-Ordinas H, Geybels MS, Grady WM, Hsu L, Hu-Lieskovan S, Huyghe JR, Kim YJ, Krystofinski P, Leiserson MDM, Montoya DJ, Nadel BB, Pellegrini M, Pritchard CC, Puig-Saus C, Quist EH, Raphael BJ, Salipante SJ, Shin DS, Shinbrot E, Shirts B, Shukla S, Stanford JL, Sun W, Tsoi J, Upfill-Brown A, Wheeler DA, Wu CJ, Yu M, Zaidi SH, Zaretsky JM, Gabriel SB, Lander ES, Garraway LA, Hudson TJ, Fuchs CS, Ribas A, Ogino S, Peters U.

Cancer Discov. 2018 Jun;8(6):730-749. doi: 10.1158/2159-8290.CD-17-1327. Epub 2018 Mar 6.

2.

Promoter methylation of ITF2, but not APC, is associated with microsatellite instability in two populations of colorectal cancer patients.

Savio AJ, Daftary D, Dicks E, Buchanan DD, Parfrey PS, Young JP, Weisenberger D, Green RC, Gallinger S, McLaughlin JR, Knight JA, Bapat B.

BMC Cancer. 2016 Feb 17;16:113. doi: 10.1186/s12885-016-2149-9.

3.

Low density of FOXP3-positive T cells in normal colonic mucosa is related to the presence of beta2-microglobulin mutations in Lynch syndrome-associated colorectal cancer.

Echterdiek F, Janikovits J, Staffa L, Müller M, Lahrmann B, Frühschütz M, Hartog B, Nelius N, Benner A, Tariverdian M, von Knebel Doeberitz M, Grabe N, Kloor M.

Oncoimmunology. 2015 Nov 11;5(2):e1075692. eCollection 2016 Feb.

4.

High numbers of PDCD1 (PD-1)-positive T cells and B2M mutations in microsatellite-unstable colorectal cancer.

Janikovits J, Müller M, Krzykalla J, Körner S, Echterdiek F, Lahrmann B, Grabe N, Schneider M, Benner A, Doeberitz MVK, Kloor M.

Oncoimmunology. 2017 Nov 6;7(2):e1390640. doi: 10.1080/2162402X.2017.1390640. eCollection 2018.

5.

Multilevel genomics of colorectal cancers with microsatellite instability-clinical impact of JAK1 mutations and consensus molecular subtype 1.

Sveen A, Johannessen B, Tengs T, Danielsen SA, Eilertsen IA, Lind GE, Berg KCG, Leithe E, Meza-Zepeda LA, Domingo E, Myklebost O, Kerr D, Tomlinson I, Nesbakken A, Skotheim RI, Lothe RA.

Genome Med. 2017 May 24;9(1):46. doi: 10.1186/s13073-017-0434-0.

6.
7.

Frequent alterations in the Wnt signaling pathway in colorectal cancer with microsatellite instability.

Shimizu Y, Ikeda S, Fujimori M, Kodama S, Nakahara M, Okajima M, Asahara T.

Genes Chromosomes Cancer. 2002 Jan;33(1):73-81.

PMID:
11746989
8.

Differential Wnt pathway gene expression and E-cadherin truncation in sporadic colorectal cancers with and without microsatellite instability.

Ortega P, Morán A, de Juan C, Frías C, Hernández S, López-Asenjo JA, Sánchez-Pernaute A, Torres A, Iniesta P, Benito M.

Clin Cancer Res. 2008 Feb 15;14(4):995-1001. doi: 10.1158/1078-0432.CCR-07-1588.

9.

Intrinsic Resistance to Immune Checkpoint Blockade in a Mismatch Repair-Deficient Colorectal Cancer.

Gurjao C, Liu D, Hofree M, AlDubayan SH, Wakiro I, Su MJ, Felt K, Gjini E, Brais LK, Rotem A, Rosenthal MH, Rozenblatt-Rosen O, Rodig S, Ng K, Van Allen EM, Corsello SM, Ogino S, Regev A, Nowak JA, Giannakis M.

Cancer Immunol Res. 2019 Jun 19. doi: 10.1158/2326-6066.CIR-18-0683. [Epub ahead of print]

PMID:
31217164
10.

Features of colorectal cancers with high-level microsatellite instability occurring in familial and sporadic settings: parallel pathways of tumorigenesis.

Young J, Simms LA, Biden KG, Wynter C, Whitehall V, Karamatic R, George J, Goldblatt J, Walpole I, Robin SA, Borten MM, Stitz R, Searle J, McKeone D, Fraser L, Purdie DR, Podger K, Price R, Buttenshaw R, Walsh MD, Barker M, Leggett BA, Jass JR.

Am J Pathol. 2001 Dec;159(6):2107-16.

11.

HNPCC versus sporadic microsatellite-unstable colon cancers follow different routes toward loss of HLA class I expression.

Dierssen JW, de Miranda NF, Ferrone S, van Puijenbroek M, Cornelisse CJ, Fleuren GJ, van Wezel T, Morreau H.

BMC Cancer. 2007 Feb 22;7:33.

12.

Promoter methylation of Wnt antagonists DKK1 and SFRP1 is associated with opposing tumor subtypes in two large populations of colorectal cancer patients.

Rawson JB, Manno M, Mrkonjic M, Daftary D, Dicks E, Buchanan DD, Younghusband HB, Parfrey PS, Young JP, Pollett A, Green RC, Gallinger S, McLaughlin JR, Knight JA, Bapat B.

Carcinogenesis. 2011 May;32(5):741-7. doi: 10.1093/carcin/bgr020. Epub 2011 Feb 8.

13.

Complex pattern of immune evasion in MSI colorectal cancer.

Ozcan M, Janikovits J, von Knebel Doeberitz M, Kloor M.

Oncoimmunology. 2018 Mar 26;7(7):e1445453. doi: 10.1080/2162402X.2018.1445453. eCollection 2018.

14.

Mutations in the WTX-gene are found in some high-grade microsatellite instable (MSI-H) colorectal cancers.

Scheel SK, Porzner M, Pfeiffer S, Ormanns S, Kirchner T, Jung A.

BMC Cancer. 2010 Aug 9;10:413. doi: 10.1186/1471-2407-10-413.

15.

[Going beyond microsatellite instability for immunotherapy in metastatic colorectal cancer: Consensus molecular subtypes and tumor mutational burden].

Cohen R, Heran M, Pudlarz T, Hilmi M, Tournigand C, André T, Rousseau B.

Bull Cancer. 2019 Feb;106(2):151-161. doi: 10.1016/j.bulcan.2018.09.008. Epub 2019 Jan 11. Review. French.

PMID:
30638897
16.

Frequent alterations of the beta-catenin and TCF-4 genes, but not of the APC gene, in colon cancers with high-frequency microsatellite instability.

Fukushima H, Yamamoto H, Itoh F, Horiuchi S, Min Y, Iku S, Imai K.

J Exp Clin Cancer Res. 2001 Dec;20(4):553-9.

PMID:
11876551
17.

Ca2+/nuclear factor of activated T cells signaling is enriched in early-onset rectal tumors devoid of canonical Wnt activation.

Kumar R, Raman R, Kotapalli V, Gowrishankar S, Pyne S, Pollack JR, Bashyam MD.

J Mol Med (Berl). 2018 Feb;96(2):135-146. doi: 10.1007/s00109-017-1607-4. Epub 2017 Nov 9.

PMID:
29124284
18.

Intrinsic β-catenin signaling suppresses CD8+ T-cell infiltration in colorectal cancer.

Xue J, Yu X, Xue L, Ge X, Zhao W, Peng W.

Biomed Pharmacother. 2019 Jul;115:108921. doi: 10.1016/j.biopha.2019.108921. Epub 2019 May 8.

19.

Analysis of the transcriptomic features of microsatellite instability subtype colon cancer.

Wang H, Wang X, Xu L, Zhang J, Cao H.

BMC Cancer. 2019 Jun 20;19(1):605. doi: 10.1186/s12885-019-5802-2.

20.

Molecular pathological classification of colorectal cancer.

Müller MF, Ibrahim AE, Arends MJ.

Virchows Arch. 2016 Aug;469(2):125-34. doi: 10.1007/s00428-016-1956-3. Epub 2016 Jun 20. Review.

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