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Items: 1 to 20 of 112

1.

Circadian Control of DRP1 Activity Regulates Mitochondrial Dynamics and Bioenergetics.

Schmitt K, Grimm A, Dallmann R, Oettinghaus B, Restelli LM, Witzig M, Ishihara N, Mihara K, Ripperger JA, Albrecht U, Frank S, Brown SA, Eckert A.

Cell Metab. 2018 Mar 6;27(3):657-666.e5. doi: 10.1016/j.cmet.2018.01.011. Epub 2018 Feb 22.

PMID:
29478834
2.

Calmodulin-dependent protein kinase II (CaMKII) mediates radiation-induced mitochondrial fission by regulating the phosphorylation of dynamin-related protein 1 (Drp1) at serine 616.

Bo T, Yamamori T, Suzuki M, Sakai Y, Yamamoto K, Inanami O.

Biochem Biophys Res Commun. 2018 Jan 8;495(2):1601-1607. doi: 10.1016/j.bbrc.2017.12.012. Epub 2017 Dec 5.

PMID:
29217195
3.

Inhibition of the mitochondrial fission protein dynamin-related protein 1 (Drp1) impairs mitochondrial fission and mitotic catastrophe after x-irradiation.

Yamamori T, Ike S, Bo T, Sasagawa T, Sakai Y, Suzuki M, Yamamoto K, Nagane M, Yasui H, Inanami O.

Mol Biol Cell. 2015 Dec 15;26(25):4607-17. doi: 10.1091/mbc.E15-03-0181. Epub 2015 Oct 14.

4.

S6 kinase 1 plays a key role in mitochondrial morphology and cellular energy flow.

Tran Q, Jung JH, Park J, Lee H, Hong Y, Cho H, Kim M, Park S, Kwon SH, Kim SH, Thomas G, Kim KP, Cho MH, Park J.

Cell Signal. 2018 Aug;48:13-24. doi: 10.1016/j.cellsig.2018.04.002. Epub 2018 Apr 17.

PMID:
29673648
5.

AKAP1 Protects from Cerebral Ischemic Stroke by Inhibiting Drp1-Dependent Mitochondrial Fission.

Flippo KH, Gnanasekaran A, Perkins GA, Ajmal A, Merrill RA, Dickey AS, Taylor SS, McKnight GS, Chauhan AK, Usachev YM, Strack S.

J Neurosci. 2018 Sep 19;38(38):8233-8242. doi: 10.1523/JNEUROSCI.0649-18.2018. Epub 2018 Aug 9.

PMID:
30093535
6.

Signal transducer and activator of transcription 2 deficiency is a novel disorder of mitochondrial fission.

Shahni R, Cale CM, Anderson G, Osellame LD, Hambleton S, Jacques TS, Wedatilake Y, Taanman JW, Chan E, Qasim W, Plagnol V, Chalasani A, Duchen MR, Gilmour KC, Rahman S.

Brain. 2015 Oct;138(Pt 10):2834-46. doi: 10.1093/brain/awv182. Epub 2015 Jun 29.

7.

A reduction in Drp1-mediated fission compromises mitochondrial health in autosomal recessive spastic ataxia of Charlevoix Saguenay.

Bradshaw TY, Romano LE, Duncan EJ, Nethisinghe S, Abeti R, Michael GJ, Giunti P, Vermeer S, Chapple JP.

Hum Mol Genet. 2016 Aug 1;25(15):3232-3244. doi: 10.1093/hmg/ddw173. Epub 2016 Jun 10.

8.

Drp1 guarding of the mitochondrial network is important for glucose-stimulated insulin secretion in pancreatic beta cells.

Reinhardt F, Schultz J, Waterstradt R, Baltrusch S.

Biochem Biophys Res Commun. 2016 Jun 10;474(4):646-651. doi: 10.1016/j.bbrc.2016.04.142. Epub 2016 May 3.

PMID:
27154223
9.

Altered Mitochondrial Dynamics and TBI Pathophysiology.

Fischer TD, Hylin MJ, Zhao J, Moore AN, Waxham MN, Dash PK.

Front Syst Neurosci. 2016 Mar 30;10:29. doi: 10.3389/fnsys.2016.00029. eCollection 2016.

10.

A mitochondrial delicacy: dynamin-related protein 1 and mitochondrial dynamics.

Breitzig MT, Alleyn MD, Lockey RF, Kolliputi N.

Am J Physiol Cell Physiol. 2018 Jul 1;315(1):C80-C90. doi: 10.1152/ajpcell.00042.2018. Epub 2018 Apr 18.

PMID:
29669222
11.

Direct Substrate Delivery Into Mitochondrial Fission-Deficient Pancreatic Islets Rescues Insulin Secretion.

Kabra UD, Pfuhlmann K, Migliorini A, Keipert S, Lamp D, Korsgren O, Gegg M, Woods SC, Pfluger PT, Lickert H, Affourtit C, Tschöp MH, Jastroch M.

Diabetes. 2017 May;66(5):1247-1257. doi: 10.2337/db16-1088. Epub 2017 Feb 7. Erratum in: Diabetes. 2017 Dec;66(12 ):3144.

12.

The cyclophilin D/Drp1 axis regulates mitochondrial fission contributing to oxidative stress-induced mitochondrial dysfunctions in SH-SY5Y cells.

Xiao A, Gan X, Chen R, Ren Y, Yu H, You C.

Biochem Biophys Res Commun. 2017 Jan 29;483(1):765-771. doi: 10.1016/j.bbrc.2016.12.068. Epub 2016 Dec 18.

PMID:
27993675
13.

RhoA regulates Drp1 mediated mitochondrial fission through ROCK to protect cardiomyocytes.

Brand CS, Tan VP, Brown JH, Miyamoto S.

Cell Signal. 2018 Oct;50:48-57. doi: 10.1016/j.cellsig.2018.06.012. Epub 2018 Jun 25.

PMID:
29953931
14.

Circadian Regulation of Mitochondrial Dynamics in Retinal Photoreceptors.

Chang JY, Shi L, Ko ML, Ko GY.

J Biol Rhythms. 2018 Apr;33(2):151-165. doi: 10.1177/0748730418762152.

PMID:
29671706
15.

Dynamin-related protein 1 is required for normal mitochondrial bioenergetic and synaptic function in CA1 hippocampal neurons.

Shields LY, Kim H, Zhu L, Haddad D, Berthet A, Pathak D, Lam M, Ponnusamy R, Diaz-Ramirez LG, Gill TM, Sesaki H, Mucke L, Nakamura K.

Cell Death Dis. 2015 Apr 16;6:e1725. doi: 10.1038/cddis.2015.94.

16.

A threshold of transmembrane potential is required for mitochondrial dynamic balance mediated by DRP1 and OMA1.

Jones E, Gaytan N, Garcia I, Herrera A, Ramos M, Agarwala D, Rana M, Innis-Whitehouse W, Schuenzel E, Gilkerson R.

Cell Mol Life Sci. 2017 Apr;74(7):1347-1363. doi: 10.1007/s00018-016-2421-9. Epub 2016 Nov 17.

17.

[Mechanism of mitochondrial fission - structure and function of Drp1 protein].

Michalska B, Duszyński J, Szymański J.

Postepy Biochem. 2016;62(2):127-137. Review. Polish.

18.

Glucocorticoid modulation of mitochondrial function in hepatoma cells requires the mitochondrial fission protein Drp1.

Hernández-Alvarez MI, Paz JC, Sebastián D, Muñoz JP, Liesa M, Segalés J, Palacín M, Zorzano A.

Antioxid Redox Signal. 2013 Aug 1;19(4):366-78. doi: 10.1089/ars.2011.4269. Epub 2012 Aug 6.

19.

Inhibition of Mitochondrial Fission and NOX2 Expression Prevent NLRP3 Inflammasome Activation in the Endothelium: The Role of Corosolic Acid Action in the Amelioration of Endothelial Dysfunction.

Li Y, Zhou ZH, Chen MH, Yang J, Leng J, Cao GS, Xin GZ, Liu LF, Kou JP, Liu BL, Li P, Wen XD.

Antioxid Redox Signal. 2016 Jun 1;24(16):893-908. doi: 10.1089/ars.2015.6479. Epub 2016 Mar 22.

PMID:
26869350
20.

Pharmacological activation of AMPK prevents Drp1-mediated mitochondrial fission and alleviates endoplasmic reticulum stress-associated endothelial dysfunction.

Li J, Wang Y, Wang Y, Wen X, Ma XN, Chen W, Huang F, Kou J, Qi LW, Liu B, Liu K.

J Mol Cell Cardiol. 2015 Sep;86:62-74. doi: 10.1016/j.yjmcc.2015.07.010. Epub 2015 Jul 18.

PMID:
26196303

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