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Items: 1 to 20 of 103

1.

Deletion of Adipose Triglyceride Lipase Links Triacylglycerol Accumulation to a More-Aggressive Phenotype in A549 Lung Carcinoma Cells.

Tomin T, Fritz K, Gindlhuber J, Waldherr L, Pucher B, Thallinger GG, Nomura DK, Schittmayer M, Birner-Gruenberger R.

J Proteome Res. 2018 Apr 6;17(4):1415-1425. doi: 10.1021/acs.jproteome.7b00782. Epub 2018 Mar 7.

PMID:
29457907
2.

Loss of adipose triglyceride lipase is associated with human cancer and induces mouse pulmonary neoplasia.

Al-Zoughbi W, Pichler M, Gorkiewicz G, Guertl-Lackner B, Haybaeck J, Jahn SW, Lackner C, Liegl-Atzwanger B, Popper H, Schauer S, Nusshold E, Kindt AS, Trajanoski Z, Speicher MR, Haemmerle G, Zimmermann R, Zechner R, Vesely PW, Hoefler G.

Oncotarget. 2016 Jun 7;7(23):33832-40. doi: 10.18632/oncotarget.9418.

3.

Inhibition of adipose triglyceride lipase (ATGL) by the putative tumor suppressor G0S2 or a small molecule inhibitor attenuates the growth of cancer cells.

Zagani R, El-Assaad W, Gamache I, Teodoro JG.

Oncotarget. 2015 Sep 29;6(29):28282-95. doi: 10.18632/oncotarget.5061.

4.

Adipose triglyceride lipase affects triacylglycerol metabolism at brain barriers.

Etschmaier K, Becker T, Eichmann TO, Schweinzer C, Scholler M, Tam-Amersdorfer C, Poeckl M, Schuligoi R, Kober A, Chirackal Manavalan AP, Rechberger GN, Streith IE, Zechner R, Zimmermann R, Panzenboeck U.

J Neurochem. 2011 Dec;119(5):1016-28. doi: 10.1111/j.1471-4159.2011.07498.x. Epub 2011 Oct 20.

5.

Adipose triglyceride lipase deficiency causes tissue-specific changes in insulin signaling.

Kienesberger PC, Lee D, Pulinilkunnil T, Brenner DS, Cai L, Magnes C, Koefeler HC, Streith IE, Rechberger GN, Haemmerle G, Flier JS, Zechner R, Kim YB, Kershaw EE.

J Biol Chem. 2009 Oct 30;284(44):30218-29. doi: 10.1074/jbc.M109.047787. Epub 2009 Aug 31.

6.

Identification of a novel phosphorylation site in adipose triglyceride lipase as a regulator of lipid droplet localization.

Xie X, Langlais P, Zhang X, Heckmann BL, Saarinen AM, Mandarino LJ, Liu J.

Am J Physiol Endocrinol Metab. 2014 Jun 15;306(12):E1449-59. doi: 10.1152/ajpendo.00663.2013. Epub 2014 May 6.

7.

The hepatitis C virus core protein inhibits adipose triglyceride lipase (ATGL)-mediated lipid mobilization and enhances the ATGL interaction with comparative gene identification 58 (CGI-58) and lipid droplets.

Camus G, Schweiger M, Herker E, Harris C, Kondratowicz AS, Tsou CL, Farese RV Jr, Herath K, Previs SF, Roddy TP, Pinto S, Zechner R, Ott M.

J Biol Chem. 2014 Dec 26;289(52):35770-80. doi: 10.1074/jbc.M114.587816. Epub 2014 Nov 7.

8.

Efficient phagocytosis requires triacylglycerol hydrolysis by adipose triglyceride lipase.

Chandak PG, Radovic B, Aflaki E, Kolb D, Buchebner M, Fröhlich E, Magnes C, Sinner F, Haemmerle G, Zechner R, Tabas I, Levak-Frank S, Kratky D.

J Biol Chem. 2010 Jun 25;285(26):20192-201. doi: 10.1074/jbc.M110.107854. Epub 2010 Apr 27.

9.

Long-chain fatty acid triglyceride (TG) metabolism disorder impairs male fertility: a study using adipose triglyceride lipase deficient mice.

Masaki H, Kim N, Nakamura H, Kumasawa K, Kamata E, Hirano KI, Kimura T.

Mol Hum Reprod. 2017 Jul 1;23(7):452-460. doi: 10.1093/molehr/gax031.

PMID:
28510703
10.

Cardiac oxidative stress in a mouse model of neutral lipid storage disease.

Schrammel A, Mussbacher M, Winkler S, Haemmerle G, Stessel H, Wölkart G, Zechner R, Mayer B.

Biochim Biophys Acta. 2013 Nov;1831(11):1600-8. doi: 10.1016/j.bbalip.2013.07.004. Epub 2013 Jul 15.

11.

[Adipose triglyceride lipase regulates adipocyte lipolysis].

Xu C, Xu GH.

Sheng Li Ke Xue Jin Zhan. 2008 Jan;39(1):10-4. Review. Chinese.

PMID:
18357681
12.

Adipose triglyceride lipase is a TG hydrolase of the small intestine and regulates intestinal PPARα signaling.

Obrowsky S, Chandak PG, Patankar JV, Povoden S, Schlager S, Kershaw EE, Bogner-Strauss JG, Hoefler G, Levak-Frank S, Kratky D.

J Lipid Res. 2013 Feb;54(2):425-35. doi: 10.1194/jlr.M031716. Epub 2012 Dec 6.

13.

Fat-specific protein 27 (FSP27) interacts with adipose triglyceride lipase (ATGL) to regulate lipolysis and insulin sensitivity in human adipocytes.

Grahn TH, Kaur R, Yin J, Schweiger M, Sharma VM, Lee MJ, Ido Y, Smas CM, Zechner R, Lass A, Puri V.

J Biol Chem. 2014 Apr 25;289(17):12029-39. doi: 10.1074/jbc.M113.539890. Epub 2014 Mar 13.

14.
15.

Adipose triglyceride lipase regulates lipid metabolism in dairy goat mammary epithelial cells.

Li J, Luo J, Wang H, Shi H, Zhu J, Sun Y, Yu K, Yao D.

Gene. 2015 Jan 1;554(1):125-30. doi: 10.1016/j.gene.2014.10.020. Epub 2014 Oct 11.

PMID:
25307872
16.

Reduced expression of adipose triglyceride lipase enhances tumor necrosis factor alpha-induced intercellular adhesion molecule-1 expression in human aortic endothelial cells via protein kinase C-dependent activation of nuclear factor-kappaB.

Inoue T, Kobayashi K, Inoguchi T, Sonoda N, Fujii M, Maeda Y, Fujimura Y, Miura D, Hirano K, Takayanagi R.

J Biol Chem. 2011 Sep 16;286(37):32045-53. doi: 10.1074/jbc.M111.285650. Epub 2011 Aug 2.

17.

The lack of the C-terminal domain of adipose triglyceride lipase causes neutral lipid storage disease through impaired interactions with lipid droplets.

Kobayashi K, Inoguchi T, Maeda Y, Nakashima N, Kuwano A, Eto E, Ueno N, Sasaki S, Sawada F, Fujii M, Matoba Y, Sumiyoshi S, Kawate H, Takayanagi R.

J Clin Endocrinol Metab. 2008 Jul;93(7):2877-84. doi: 10.1210/jc.2007-2247. Epub 2008 Apr 29.

PMID:
18445677
18.

Adipose triglyceride lipase is a major hepatic lipase that regulates triacylglycerol turnover and fatty acid signaling and partitioning.

Ong KT, Mashek MT, Bu SY, Greenberg AS, Mashek DG.

Hepatology. 2011 Jan;53(1):116-26. doi: 10.1002/hep.24006. Epub 2010 Oct 21.

19.

Adipose triglyceride lipase activity is inhibited by long-chain acyl-coenzyme A.

Nagy HM, Paar M, Heier C, Moustafa T, Hofer P, Haemmerle G, Lass A, Zechner R, Oberer M, Zimmermann R.

Biochim Biophys Acta. 2014 Apr 4;1841(4):588-94. doi: 10.1016/j.bbalip.2014.01.005. Epub 2014 Jan 16.

20.

Absence of adipose triglyceride lipase protects from hepatic endoplasmic reticulum stress in mice.

Fuchs CD, Claudel T, Kumari P, Haemmerle G, Pollheimer MJ, Stojakovic T, Scharnagl H, Halilbasic E, Gumhold J, Silbert D, Koefeler H, Trauner M.

Hepatology. 2012 Jul;56(1):270-80. doi: 10.1002/hep.25601. Epub 2012 May 29.

PMID:
22271167

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