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Items: 1 to 20 of 105


RAGE Deletion Confers Renoprotection by Reducing Responsiveness to Transforming Growth Factor-β and Increasing Resistance to Apoptosis.

Hagiwara S, Sourris K, Ziemann M, Tieqiao W, Mohan M, McClelland AD, Brennan E, Forbes J, Coughlan M, Harcourt B, Penfold S, Wang B, Higgins G, Pickering R, El-Osta A, Thomas MC, Cooper ME, Kantharidis P.

Diabetes. 2018 May;67(5):960-973. doi: 10.2337/db17-0538. Epub 2018 Feb 15.


RAGE-Aptamer Blocks the Development and Progression of Experimental Diabetic Nephropathy.

Matsui T, Higashimoto Y, Nishino Y, Nakamura N, Fukami K, Yamagishi SI.

Diabetes. 2017 Jun;66(6):1683-1695. doi: 10.2337/db16-1281. Epub 2017 Apr 6.


The anti-inflammation effect of Moutan Cortex on advanced glycation end products-induced rat mesangial cells dysfunction and High-glucose-fat diet and streptozotocin-induced diabetic nephropathy rats.

Zhang MH, Feng L, Zhu MM, Gu JF, Jiang J, Cheng XD, Ding SM, Wu C, Jia XB.

J Ethnopharmacol. 2014;151(1):591-600. doi: 10.1016/j.jep.2013.11.015. Epub 2013 Nov 21.


Repression of let-7 by transforming growth factor-β1-induced Lin28 upregulates collagen expression in glomerular mesangial cells under diabetic conditions.

Park JT, Kato M, Lanting L, Castro N, Nam BY, Wang M, Kang SW, Natarajan R.

Am J Physiol Renal Physiol. 2014 Dec 15;307(12):F1390-403. doi: 10.1152/ajprenal.00458.2014. Epub 2014 Oct 29.


MCP-1/CCR2 system is involved in high glucose-induced fibronectin and type IV collagen expression in cultured mesangial cells.

Park J, Ryu DR, Li JJ, Jung DS, Kwak SJ, Lee SH, Yoo TH, Han SH, Lee JE, Kim DK, Moon SJ, Kim K, Han DS, Kang SW.

Am J Physiol Renal Physiol. 2008 Sep;295(3):F749-57. doi: 10.1152/ajprenal.00547.2007. Epub 2008 Jun 25.


Monocyte chemoattractant protein-1 has prosclerotic effects both in a mouse model of experimental diabetes and in vitro in human mesangial cells.

Giunti S, Tesch GH, Pinach S, Burt DJ, Cooper ME, Cavallo-Perin P, Camussi G, Gruden G.

Diabetologia. 2008 Jan;51(1):198-207. Epub 2007 Oct 30.


Osteomeles schwerinae extracts inhibits the binding to receptors of advanced glycation end products and TGF-β1 expression in mesangial cells under diabetic conditions.

Kim YS, Jung DH, Lee IS, Pyun BJ, Kim JS.

Phytomedicine. 2016 Apr 15;23(4):388-97. doi: 10.1016/j.phymed.2016.02.005. Epub 2016 Feb 21.


SND p102 promotes extracellular matrix accumulation and cell proliferation in rat glomerular mesangial cells via the AT1R/ERK/Smad3 pathway.

Xu JL, Gan XX, Ni J, Shao DC, Shen Y, Miao NJ, Xu D, Zhou L, Zhang W, Lu LM.

Acta Pharmacol Sin. 2018 Sep;39(9):1513-1521. doi: 10.1038/aps.2017.184. Epub 2018 May 10.


Ager Deletion Enhances Ischemic Muscle Inflammation, Angiogenesis, and Blood Flow Recovery in Diabetic Mice.

López-Díez R, Shen X, Daffu G, Khursheed M, Hu J, Song F, Rosario R, Xu Y, Li Q, Xi X, Zou YS, Li H, Schmidt AM, Yan SF.

Arterioscler Thromb Vasc Biol. 2017 Aug;37(8):1536-1547. doi: 10.1161/ATVBAHA.117.309714. Epub 2017 Jun 22.


Advanced glycation end products decrease mesangial cell MMP-7: a role in matrix accumulation in diabetic nephropathy?

McLennan SV, Kelly DJ, Schache M, Waltham M, Dy V, Langham RG, Yue DK, Gilbert RE.

Kidney Int. 2007 Aug;72(4):481-8. Epub 2007 Jun 6.


Deletion of p66Shc longevity gene protects against experimental diabetic glomerulopathy by preventing diabetes-induced oxidative stress.

Menini S, Amadio L, Oddi G, Ricci C, Pesce C, Pugliese F, Giorgio M, Migliaccio E, Pelicci P, Iacobini C, Pugliese G.

Diabetes. 2006 Jun;55(6):1642-50. Erratum in: Diabetes. 2017 Oct 24;:.


The effect of resveratrol on the expression of AdipoR1 in kidneys of diabetic nephropathy.

Ji H, Wu L, Ma X, Ma X, Qin G.

Mol Biol Rep. 2014;41(4):2151-9. doi: 10.1007/s11033-014-3064-2. Epub 2014 Jan 12.


Berberine exerts renoprotective effects by regulating the AGEs-RAGE signaling pathway in mesangial cells during diabetic nephropathy.

Qiu YY, Tang LQ, Wei W.

Mol Cell Endocrinol. 2017 Mar 5;443:89-105. doi: 10.1016/j.mce.2017.01.009. Epub 2017 Jan 10.


Podocyte-specific chemokine (C-C motif) receptor 2 overexpression mediates diabetic renal injury in mice.

You H, Gao T, Raup-Konsavage WM, Cooper TK, Bronson SK, Reeves WB, Awad AS.

Kidney Int. 2017 Mar;91(3):671-682. doi: 10.1016/j.kint.2016.09.042. Epub 2016 Dec 1.


Contribution of myo-inositol oxygenase in AGE:RAGE-mediated renal tubulointerstitial injury in the context of diabetic nephropathy.

Sharma I, Tupe RS, Wallner AK, Kanwar YS.

Am J Physiol Renal Physiol. 2018 Jan 1;314(1):F107-F121. doi: 10.1152/ajprenal.00434.2017. Epub 2017 Sep 20.


Accelerated diabetic glomerulopathy in galectin-3/AGE receptor 3 knockout mice.

Pugliese G, Pricci F, Iacobini C, Leto G, Amadio L, Barsotti P, Frigeri L, Hsu DK, Vlassara H, Liu FT, Di Mario U.

FASEB J. 2001 Nov;15(13):2471-9.


Polydatin promotes Nrf2-ARE anti-oxidative pathway through activating Sirt1 to resist AGEs-induced upregulation of fibronetin and transforming growth factor-β1 in rat glomerular messangial cells.

Huang K, Chen C, Hao J, Huang J, Wang S, Liu P, Huang H.

Mol Cell Endocrinol. 2015 Jan 5;399:178-89. doi: 10.1016/j.mce.2014.08.014. Epub 2014 Sep 2.


Protective role of cannabinoid receptor type 2 in a mouse model of diabetic nephropathy.

Barutta F, Piscitelli F, Pinach S, Bruno G, Gambino R, Rastaldi MP, Salvidio G, Di Marzo V, Cavallo Perin P, Gruden G.

Diabetes. 2011 Sep;60(9):2386-96. doi: 10.2337/db10-1809. Epub 2011 Aug 1.


Fucoidan exerts protective effects against diabetic nephropathy related to spontaneous diabetes through the NF-κB signaling pathway in vivo and in vitro.

Wang Y, Nie M, Lu Y, Wang R, Li J, Yang B, Xia M, Zhang H, Li X.

Int J Mol Med. 2015 Apr;35(4):1067-73. doi: 10.3892/ijmm.2015.2095. Epub 2015 Feb 9.


Transforming growth factor β1 (TGF-β1) enhances expression of profibrotic genes through a novel signaling cascade and microRNAs in renal mesangial cells.

Castro NE, Kato M, Park JT, Natarajan R.

J Biol Chem. 2014 Oct 17;289(42):29001-13. doi: 10.1074/jbc.M114.600783. Epub 2014 Sep 9.

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