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Items: 1 to 20 of 99

1.

Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids.

Kasendra M, Tovaglieri A, Sontheimer-Phelps A, Jalili-Firoozinezhad S, Bein A, Chalkiadaki A, Scholl W, Zhang C, Rickner H, Richmond CA, Li H, Breault DT, Ingber DE.

Sci Rep. 2018 Feb 13;8(1):2871. doi: 10.1038/s41598-018-21201-7.

2.

Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow.

Kim HJ, Huh D, Hamilton G, Ingber DE.

Lab Chip. 2012 Jun 21;12(12):2165-74. doi: 10.1039/c2lc40074j. Epub 2012 Mar 20.

PMID:
22434367
3.

Enhanced Utilization of Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids Using Microengineered Chips.

Workman MJ, Gleeson JP, Troisi EJ, Estrada HQ, Kerns SJ, Hinojosa CD, Hamilton GA, Targan SR, Svendsen CN, Barrett RJ.

Cell Mol Gastroenterol Hepatol. 2017 Dec 29;5(4):669-677.e2. doi: 10.1016/j.jcmgh.2017.12.008. eCollection 2018.

4.

Human Lung Small Airway-on-a-Chip Protocol.

Benam KH, Mazur M, Choe Y, Ferrante TC, Novak R, Ingber DE.

Methods Mol Biol. 2017;1612:345-365. doi: 10.1007/978-1-4939-7021-6_25.

PMID:
28634955
5.

Gut-on-a-Chip microenvironment induces human intestinal cells to undergo villus differentiation.

Kim HJ, Ingber DE.

Integr Biol (Camb). 2013 Sep;5(9):1130-40. doi: 10.1039/c3ib40126j.

PMID:
23817533
6.

Co-culture of Living Microbiome with Microengineered Human Intestinal Villi in a Gut-on-a-Chip Microfluidic Device.

Kim HJ, Lee J, Choi JH, Bahinski A, Ingber DE.

J Vis Exp. 2016 Aug 30;(114). doi: 10.3791/54344.

7.

Pathomimetic modeling of human intestinal diseases and underlying host-gut microbiome interactions in a gut-on-a-chip.

Shin W, Kim HJ.

Methods Cell Biol. 2018;146:135-148. doi: 10.1016/bs.mcb.2018.05.006. Epub 2018 Jun 25.

PMID:
30037458
8.

Microfluidic Organ-on-a-Chip Models of Human Intestine.

Bein A, Shin W, Jalili-Firoozinezhad S, Park MH, Sontheimer-Phelps A, Tovaglieri A, Chalkiadaki A, Kim HJ, Ingber DE.

Cell Mol Gastroenterol Hepatol. 2018 Apr 24;5(4):659-668. doi: 10.1016/j.jcmgh.2017.12.010. eCollection 2018. Review.

9.

Human Gut-On-A-Chip Supports Polarized Infection of Coxsackie B1 Virus In Vitro.

Villenave R, Wales SQ, Hamkins-Indik T, Papafragkou E, Weaver JC, Ferrante TC, Bahinski A, Elkins CA, Kulka M, Ingber DE.

PLoS One. 2017 Feb 1;12(2):e0169412. doi: 10.1371/journal.pone.0169412. eCollection 2017.

10.

A Biomimetic Human Gut-on-a-Chip for Modeling Drug Metabolism in Intestine.

Guo Y, Li Z, Su W, Wang L, Zhu Y, Qin J.

Artif Organs. 2018 Sep 5. doi: 10.1111/aor.13163. [Epub ahead of print]

PMID:
30256442
11.

Establishment of human epithelial enteroids and colonoids from whole tissue and biopsy.

Mahe MM, Sundaram N, Watson CL, Shroyer NF, Helmrath MA.

J Vis Exp. 2015 Mar 6;(97). doi: 10.3791/52483.

12.

Brief summary of the current protocols for generating intestinal organoids.

Miura S, Suzuki A.

Dev Growth Differ. 2018 Aug;60(6):387-392. doi: 10.1111/dgd.12559. Epub 2018 Jul 23. Review.

PMID:
30039581
13.

Microfabrication of human organs-on-chips.

Huh D, Kim HJ, Fraser JP, Shea DE, Khan M, Bahinski A, Hamilton GA, Ingber DE.

Nat Protoc. 2013 Nov;8(11):2135-57. doi: 10.1038/nprot.2013.137. Epub 2013 Oct 10.

PMID:
24113786
14.

Human and mouse tissue-engineered small intestine both demonstrate digestive and absorptive function.

Grant CN, Mojica SG, Sala FG, Hill JR, Levin DE, Speer AL, Barthel ER, Shimada H, Zachos NC, Grikscheit TC.

Am J Physiol Gastrointest Liver Physiol. 2015 Apr 15;308(8):G664-77. doi: 10.1152/ajpgi.00111.2014. Epub 2015 Jan 8.

15.

Intestinal epithelial organoids fuse to form self-organizing tubes in floating collagen gels.

Sachs N, Tsukamoto Y, Kujala P, Peters PJ, Clevers H.

Development. 2017 Mar 15;144(6):1107-1112. doi: 10.1242/dev.143933.

16.

In vitro patterning of pluripotent stem cell-derived intestine recapitulates in vivo human development.

Tsai YH, Nattiv R, Dedhia PH, Nagy MS, Chin AM, Thomson M, Klein OD, Spence JR.

Development. 2017 Mar 15;144(6):1045-1055. doi: 10.1242/dev.138453. Epub 2016 Dec 7.

17.

Robust bioengineered 3D functional human intestinal epithelium.

Chen Y, Lin Y, Davis KM, Wang Q, Rnjak-Kovacina J, Li C, Isberg RR, Kumamoto CA, Mecsas J, Kaplan DL.

Sci Rep. 2015 Sep 16;5:13708. doi: 10.1038/srep13708.

18.

Generation of neomucosa in vivo by transplantation of dissociated rat postnatal small intestinal epithelium.

Tait IS, Flint N, Campbell FC, Evans GS.

Differentiation. 1994 Apr;56(1-2):91-100.

PMID:
8026650
19.

Development of an Advanced Primary Human In Vitro Model of the Small Intestine.

Schweinlin M, Wilhelm S, Schwedhelm I, Hansmann J, Rietscher R, Jurowich C, Walles H, Metzger M.

Tissue Eng Part C Methods. 2016 Sep;22(9):873-83. doi: 10.1089/ten.TEC.2016.0101. Epub 2016 Aug 22.

PMID:
27481569
20.

Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium.

Sato T, Stange DE, Ferrante M, Vries RG, Van Es JH, Van den Brink S, Van Houdt WJ, Pronk A, Van Gorp J, Siersema PD, Clevers H.

Gastroenterology. 2011 Nov;141(5):1762-72. doi: 10.1053/j.gastro.2011.07.050. Epub 2011 Sep 2.

PMID:
21889923

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