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Items: 1 to 20 of 100

1.

TBK1 at the Crossroads of Inflammation and Energy Homeostasis in Adipose Tissue.

Zhao P, Wong KI, Sun X, Reilly SM, Uhm M, Liao Z, Skorobogatko Y, Saltiel AR.

Cell. 2018 Feb 8;172(4):731-743.e12. doi: 10.1016/j.cell.2018.01.007.

2.

Inflammation produces catecholamine resistance in obesity via activation of PDE3B by the protein kinases IKKε and TBK1.

Mowers J, Uhm M, Reilly SM, Simon J, Leto D, Chiang SH, Chang L, Saltiel AR.

Elife. 2013 Dec 24;2:e01119. doi: 10.7554/eLife.01119.

3.

TANK-binding kinase 1 (TBK1) modulates inflammatory hyperalgesia by regulating MAP kinases and NF-κB dependent genes.

Möser CV, Stephan H, Altenrath K, Kynast KL, Russe OQ, Olbrich K, Geisslinger G, Niederberger E.

J Neuroinflammation. 2015 May 23;12:100. doi: 10.1186/s12974-015-0319-3.

4.

Activation of AMP-activated protein kinase rapidly suppresses multiple pro-inflammatory pathways in adipocytes including IL-1 receptor-associated kinase-4 phosphorylation.

Mancini SJ, White AD, Bijland S, Rutherford C, Graham D, Richter EA, Viollet B, Touyz RM, Palmer TM, Salt IP.

Mol Cell Endocrinol. 2017 Jan 15;440:44-56. doi: 10.1016/j.mce.2016.11.010. Epub 2016 Nov 11.

5.

Induced adiposity and adipocyte hypertrophy in mice lacking the AMP-activated protein kinase-alpha2 subunit.

Villena JA, Viollet B, Andreelli F, Kahn A, Vaulont S, Sul HS.

Diabetes. 2004 Sep;53(9):2242-9.

6.

IL-17 axis accelerates the inflammatory progression of obese in mice via TBK1 and IKBKE pathway.

Lee SH, Jhun J, Byun JK, Kim EK, Jung K, Lee JE, Choi JY, Park SH, Cho ML.

Immunol Lett. 2017 Apr;184:67-75. doi: 10.1016/j.imlet.2017.02.004. Epub 2017 Feb 22.

PMID:
28237848
7.

Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders.

Kauppinen A, Suuronen T, Ojala J, Kaarniranta K, Salminen A.

Cell Signal. 2013 Oct;25(10):1939-48. doi: 10.1016/j.cellsig.2013.06.007. Epub 2013 Jun 11. Review.

PMID:
23770291
8.

IKK promotes cytokine-induced and cancer-associated AMPK activity and attenuates phenformin-induced cell death in LKB1-deficient cells.

Antonia RJ, Baldwin AS.

Sci Signal. 2018 Jul 10;11(538). pii: eaan5850. doi: 10.1126/scisignal.aan5850.

9.
10.

Activation of pattern recognition receptors in brown adipocytes induces inflammation and suppresses uncoupling protein 1 expression and mitochondrial respiration.

Bae J, Ricciardi CJ, Esposito D, Komarnytsky S, Hu P, Curry BJ, Brown PL, Gao Z, Biggerstaff JP, Chen J, Zhao L.

Am J Physiol Cell Physiol. 2014 May 15;306(10):C918-30. doi: 10.1152/ajpcell.00249.2013. Epub 2014 Mar 13.

11.

IL-37 protects against obesity-induced inflammation and insulin resistance.

Ballak DB, van Diepen JA, Moschen AR, Jansen HJ, Hijmans A, Groenhof GJ, Leenders F, Bufler P, Boekschoten MV, Müller M, Kersten S, Li S, Kim S, Eini H, Lewis EC, Joosten LA, Tilg H, Netea MG, Tack CJ, Dinarello CA, Stienstra R.

Nat Commun. 2014 Sep 3;5:4711. doi: 10.1038/ncomms5711. Erratum in: Nat Commun. 2015;6:6039.

PMID:
25182023
12.

The kinase TBK1 controls IgA class switching by negatively regulating noncanonical NF-κB signaling.

Jin J, Xiao Y, Chang JH, Yu J, Hu H, Starr R, Brittain GC, Chang M, Cheng X, Sun SC.

Nat Immunol. 2012 Nov;13(11):1101-9. doi: 10.1038/ni.2423. Epub 2012 Sep 30.

13.

Corosolic acid inhibits adipose tissue inflammation and ameliorates insulin resistance via AMPK activation in high-fat fed mice.

Yang J, Leng J, Li JJ, Tang JF, Li Y, Liu BL, Wen XD.

Phytomedicine. 2016 Feb 15;23(2):181-90. doi: 10.1016/j.phymed.2015.12.018. Epub 2016 Jan 21.

PMID:
26926180
14.

Adipocytokine orosomucoid integrates inflammatory and metabolic signals to preserve energy homeostasis by resolving immoderate inflammation.

Lee YS, Choi JW, Hwang I, Lee JW, Lee JH, Kim AY, Huh JY, Koh YJ, Koh GY, Son HJ, Masuzaki H, Hotta K, Alfadda AA, Kim JB.

J Biol Chem. 2010 Jul 16;285(29):22174-85. doi: 10.1074/jbc.M109.085464. Epub 2010 May 4.

15.

ADIPOQ/adiponectin induces cytotoxic autophagy in breast cancer cells through STK11/LKB1-mediated activation of the AMPK-ULK1 axis.

Chung SJ, Nagaraju GP, Nagalingam A, Muniraj N, Kuppusamy P, Walker A, Woo J, Győrffy B, Gabrielson E, Saxena NK, Sharma D.

Autophagy. 2017 Aug 3;13(8):1386-1403. doi: 10.1080/15548627.2017.1332565. Epub 2017 Jul 11.

16.

Reduced ATGL-mediated lipolysis attenuates β-adrenergic-induced AMPK signaling, but not the induction of PKA-targeted genes, in adipocytes and adipose tissue.

MacPherson RE, Dragos SM, Ramos S, Sutton C, Frendo-Cumbo S, Castellani L, Watt MJ, Perry CG, Mutch DM, Wright DC.

Am J Physiol Cell Physiol. 2016 Aug 1;311(2):C269-76. doi: 10.1152/ajpcell.00126.2016. Epub 2016 Jun 29.

17.

Vaspin suppresses cytokine-induced inflammation in 3T3-L1 adipocytes via inhibition of NFκB pathway.

Zieger K, Weiner J, Krause K, Schwarz M, Kohn M, Stumvoll M, Blüher M, Heiker JT.

Mol Cell Endocrinol. 2018 Jan 15;460:181-188. doi: 10.1016/j.mce.2017.07.022. Epub 2017 Jul 26.

PMID:
28756250
18.

Fibroblast growth factor 21 regulates energy metabolism by activating the AMPK-SIRT1-PGC-1alpha pathway.

Chau MD, Gao J, Yang Q, Wu Z, Gromada J.

Proc Natl Acad Sci U S A. 2010 Jul 13;107(28):12553-8. doi: 10.1073/pnas.1006962107. Epub 2010 Jun 28.

19.

TANK-binding kinase 1 and Janus kinase 2 play important roles in the regulation of mitogen-activated protein kinase phosphatase-1 expression after toll-like receptor 4 activation.

Kim E, Yoon JY, Lee J, Jeong D, Park JG, Hong YH, Kim JH, Aravinthan A, Kim JH, Cho JY.

J Cell Physiol. 2018 Nov;233(11):8790-8801. doi: 10.1002/jcp.26787. Epub 2018 May 24.

PMID:
29797567
20.

Cytosolic-DNA-mediated, STING-dependent proinflammatory gene induction necessitates canonical NF-κB activation through TBK1.

Abe T, Barber GN.

J Virol. 2014 May;88(10):5328-41. doi: 10.1128/JVI.00037-14. Epub 2014 Mar 5.

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