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Items: 1 to 20 of 102

1.

ERAD-dependent control of the Wnt secretory factor Evi.

Glaeser K, Urban M, Fenech E, Voloshanenko O, Kranz D, Lari F, Christianson JC, Boutros M.

EMBO J. 2018 Feb 15;37(4). pii: e97311. doi: 10.15252/embj.201797311. Epub 2018 Jan 29.

2.

Wnt secretion is required to maintain high levels of Wnt activity in colon cancer cells.

Voloshanenko O, Erdmann G, Dubash TD, Augustin I, Metzig M, Moffa G, Hundsrucker C, Kerr G, Sandmann T, Anchang B, Demir K, Boehm C, Leible S, Ball CR, Glimm H, Spang R, Boutros M.

Nat Commun. 2013;4:2610. doi: 10.1038/ncomms3610.

3.

TMEM129 is a Derlin-1 associated ERAD E3 ligase essential for virus-induced degradation of MHC-I.

van den Boomen DJ, Timms RT, Grice GL, Stagg HR, Skødt K, Dougan G, Nathan JA, Lehner PJ.

Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):11425-30. doi: 10.1073/pnas.1409099111. Epub 2014 Jul 16.

4.

A VCP inhibitor substrate trapping approach (VISTA) enables proteomic profiling of endogenous ERAD substrates.

Huang EY, To M, Tran E, Dionisio LTA, Cho HJ, Baney KLM, Pataki CI, Olzmann JA.

Mol Biol Cell. 2018 May 1;29(9):1021-1030. doi: 10.1091/mbc.E17-08-0514. Epub 2018 Mar 22.

5.

A Cdc48 "Retrochaperone" Function Is Required for the Solubility of Retrotranslocated, Integral Membrane Endoplasmic Reticulum-associated Degradation (ERAD-M) Substrates.

Neal S, Mak R, Bennett EJ, Hampton R.

J Biol Chem. 2017 Feb 24;292(8):3112-3128. doi: 10.1074/jbc.M116.770610. Epub 2017 Jan 11.

6.

The Wnt secretion protein Evi/Gpr177 promotes glioma tumourigenesis.

Augustin I, Goidts V, Bongers A, Kerr G, Vollert G, Radlwimmer B, Hartmann C, Herold-Mende C, Reifenberger G, von Deimling A, Boutros M.

EMBO Mol Med. 2012 Jan;4(1):38-51. doi: 10.1002/emmm.201100186. Epub 2011 Dec 7.

7.

Regulation of endoplasmic reticulum-associated degradation by RNF5-dependent ubiquitination of JNK-associated membrane protein (JAMP).

Tcherpakov M, Delaunay A, Toth J, Kadoya T, Petroski MD, Ronai ZA.

J Biol Chem. 2009 May 1;284(18):12099-109. doi: 10.1074/jbc.M808222200. Epub 2009 Mar 6.

8.

Membrane Protein Quantity Control at the Endoplasmic Reticulum.

Printsev I, Curiel D, Carraway KL 3rd.

J Membr Biol. 2017 Aug;250(4):379-392. doi: 10.1007/s00232-016-9931-0. Epub 2016 Oct 14. Review.

9.
10.

The evolving role of ubiquitin modification in endoplasmic reticulum-associated degradation.

Preston GM, Brodsky JL.

Biochem J. 2017 Feb 15;474(4):445-469. doi: 10.1042/BCJ20160582. Review.

11.

USP19-Mediated Deubiquitination Facilitates the Stabilization of HRD1 Ubiquitin Ligase.

Harada K, Kato M, Nakamura N.

Int J Mol Sci. 2016 Nov 2;17(11). pii: E1829.

12.

Identification of SVIP as an endogenous inhibitor of endoplasmic reticulum-associated degradation.

Ballar P, Zhong Y, Nagahama M, Tagaya M, Shen Y, Fang S.

J Biol Chem. 2007 Nov 23;282(47):33908-14. Epub 2007 Sep 14.

13.

The VCP-UBXN1 Complex Mediates Triage of Ubiquitylated Cytosolic Proteins Bound to the BAG6 Complex.

Ganji R, Mukkavalli S, Somanji F, Raman M.

Mol Cell Biol. 2018 Jun 14;38(13). pii: e00154-18. doi: 10.1128/MCB.00154-18. Print 2018 Jul 1.

14.

Endothelial cell-derived non-canonical Wnt ligands control vascular pruning in angiogenesis.

Korn C, Scholz B, Hu J, Srivastava K, Wojtarowicz J, Arnsperger T, Adams RH, Boutros M, Augustin HG, Augustin I.

Development. 2014 Apr;141(8):1757-66. doi: 10.1242/dev.104422.

15.

Selenoprotein S is required for clearance of C99 through endoplasmic reticulum-associated degradation.

Jang JK, Park KJ, Lee JH, Ko KY, Kang S, Kim IY.

Biochem Biophys Res Commun. 2017 Apr 29;486(2):444-450. doi: 10.1016/j.bbrc.2017.03.060. Epub 2017 Mar 16.

PMID:
28315680
16.

Secretion of Wnt ligands requires Evi, a conserved transmembrane protein.

Bartscherer K, Pelte N, Ingelfinger D, Boutros M.

Cell. 2006 May 5;125(3):523-33.

17.

AAA ATPase p97/valosin-containing protein interacts with gp78, a ubiquitin ligase for endoplasmic reticulum-associated degradation.

Zhong X, Shen Y, Ballar P, Apostolou A, Agami R, Fang S.

J Biol Chem. 2004 Oct 29;279(44):45676-84. Epub 2004 Aug 24.

18.

HRD1-mediated ERAD tuning of ER-bound E2 is conserved between plants and mammals.

Chen Q, Zhong Y, Wu Y, Liu L, Wang P, Liu R, Cui F, Li Q, Yang X, Fang S, Xie Q.

Nat Plants. 2016 Jun 20;2:16094. doi: 10.1038/nplants.2016.94.

PMID:
27322605
19.

The human ubiquitin conjugating enzyme UBE2J2 (Ubc6) is a substrate for proteasomal degradation.

Lam SY, Murphy C, Foley LA, Ross SA, Wang TC, Fleming JV.

Biochem Biophys Res Commun. 2014 Aug 29;451(3):361-6. doi: 10.1016/j.bbrc.2014.07.099. Epub 2014 Jul 30.

PMID:
25083800
20.

A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation.

van de Weijer ML, Bassik MC, Luteijn RD, Voorburg CM, Lohuis MA, Kremmer E, Hoeben RC, LeProust EM, Chen S, Hoelen H, Ressing ME, Patena W, Weissman JS, McManus MT, Wiertz EJ, Lebbink RJ.

Nat Commun. 2014 May 8;5:3832. doi: 10.1038/ncomms4832.

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