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Items: 1 to 20 of 98

1.

Intracellular cavity of sensor domain controls allosteric gating of TRPA1 channel.

Zimova L, Sinica V, Kadkova A, Vyklicka L, Zima V, Barvik I, Vlachova V.

Sci Signal. 2018 Jan 23;11(514). pii: eaan8621. doi: 10.1126/scisignal.aan8621.

PMID:
29363587
2.

Structural modeling and patch-clamp analysis of pain-related mutation TRPA1-N855S reveal inter-subunit salt bridges stabilizing the channel open state.

Zíma V, Witschas K, Hynkova A, Zímová L, Barvík I, Vlachova V.

Neuropharmacology. 2015 Jun;93:294-307. doi: 10.1016/j.neuropharm.2015.02.018. Epub 2015 Feb 25.

PMID:
25724085
3.

N-terminal tetrapeptide T/SPLH motifs contribute to multimodal activation of human TRPA1 channel.

Hynkova A, Marsakova L, Vaskova J, Vlachova V.

Sci Rep. 2016 Jun 27;6:28700. doi: 10.1038/srep28700.

4.

The region adjacent to the C-end of the inner gate in transient receptor potential melastatin 8 (TRPM8) channels plays a central role in allosteric channel activation.

Taberner FJ, López-Córdoba A, Fernández-Ballester G, Korchev Y, Ferrer-Montiel A.

J Biol Chem. 2014 Oct 10;289(41):28579-94. doi: 10.1074/jbc.M114.577478. Epub 2014 Aug 25.

5.

The isolated voltage sensing domain of the Shaker potassium channel forms a voltage-gated cation channel.

Zhao J, Blunck R.

Elife. 2016 Oct 6;5. pii: e18130. doi: 10.7554/eLife.18130.

6.

Emerging issues of connexin channels: biophysics fills the gap.

Harris AL.

Q Rev Biophys. 2001 Aug;34(3):325-472. Review. Erratum in: Q Rev Biophys 2002 Feb;35(1):109.

PMID:
11838236
7.

Gating of the two-pore cation channel AtTPC1 in the plant vacuole is based on a single voltage-sensing domain.

Jaślan D, Mueller TD, Becker D, Schultz J, Cuin TA, Marten I, Dreyer I, Schönknecht G, Hedrich R.

Plant Biol (Stuttg). 2016 Sep;18(5):750-60. doi: 10.1111/plb.12478. Epub 2016 Jul 12.

PMID:
27270880
8.

A role for the S0 transmembrane segment in voltage-dependent gating of BK channels.

Koval OM, Fan Y, Rothberg BS.

J Gen Physiol. 2007 Mar;129(3):209-20. Epub 2007 Feb 12.

9.

Role of charged residues in the S1-S4 voltage sensor of BK channels.

Ma Z, Lou XJ, Horrigan FT.

J Gen Physiol. 2006 Mar;127(3):309-28.

10.

Functional validation of Ca2+-binding residues from the crystal structure of the BK ion channel.

Kshatri AS, Gonzalez-Hernandez AJ, Giraldez T.

Biochim Biophys Acta Biomembr. 2018 Apr;1860(4):943-952. doi: 10.1016/j.bbamem.2017.09.023. Epub 2017 Sep 29.

11.

A novel extracellular calcium sensing mechanism in voltage-gated potassium ion channels.

Johnson JP Jr, Balser JR, Bennett PB.

J Neurosci. 2001 Jun 15;21(12):4143-53.

12.

Pore properties of Orai1 calcium channel dimers and their activation by the STIM1 ER calcium sensor.

Cai X, Nwokonko RM, Loktionova NA, Abdulqadir R, Baraniak JH Jr, Wang Y, Trebak M, Zhou Y, Gill DL.

J Biol Chem. 2018 Aug 17;293(33):12962-12974. doi: 10.1074/jbc.RA118.003424. Epub 2018 Jun 28.

13.

Critical role of the pore domain in the cold response of TRPM8 channels identified by ortholog functional comparison.

Pertusa M, Rivera B, González A, Ugarte G, Madrid R.

J Biol Chem. 2018 Aug 10;293(32):12454-12471. doi: 10.1074/jbc.RA118.002256. Epub 2018 Jun 7.

PMID:
29880642
14.

Atomic constraints between the voltage sensor and the pore domain in a voltage-gated K+ channel of known structure.

Lewis A, Jogini V, Blachowicz L, Lainé M, Roux B.

J Gen Physiol. 2008 Jun;131(6):549-61. doi: 10.1085/jgp.200809962.

15.

The S4-S5 linker couples voltage sensing and activation of pacemaker channels.

Chen J, Mitcheson JS, Tristani-Firouzi M, Lin M, Sanguinetti MC.

Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11277-82. Epub 2001 Sep 11.

16.

Molecular determinants of coupling between the domain III voltage sensor and pore of a sodium channel.

Muroi Y, Arcisio-Miranda M, Chowdhury S, Chanda B.

Nat Struct Mol Biol. 2010 Feb;17(2):230-7. doi: 10.1038/nsmb.1749. Epub 2010 Jan 31.

17.

Conserved residues within the putative S4-S5 region serve distinct functions among thermosensitive vanilloid transient receptor potential (TRPV) channels.

Boukalova S, Marsakova L, Teisinger J, Vlachova V.

J Biol Chem. 2010 Dec 31;285(53):41455-62. doi: 10.1074/jbc.M110.145466. Epub 2010 Nov 2.

18.

Mutation of I696 and W697 in the TRP box of vanilloid receptor subtype I modulates allosteric channel activation.

Gregorio-Teruel L, Valente P, González-Ros JM, Fernández-Ballester G, Ferrer-Montiel A.

J Gen Physiol. 2014 Mar;143(3):361-75. doi: 10.1085/jgp.201311070.

19.

The First Extracellular Linker Is Important for Several Aspects of the Gating Mechanism of Human TRPA1 Channel.

Marsakova L, Barvik I, Zima V, Zimova L, Vlachova V.

Front Mol Neurosci. 2017 Jan 31;10:16. doi: 10.3389/fnmol.2017.00016. eCollection 2017.

20.

Bimodal voltage dependence of TRPA1: mutations of a key pore helix residue reveal strong intrinsic voltage-dependent inactivation.

Wan X, Lu Y, Chen X, Xiong J, Zhou Y, Li P, Xia B, Li M, Zhu MX, Gao Z.

Pflugers Arch. 2014 Jul;466(7):1273-87. doi: 10.1007/s00424-013-1345-6. Epub 2013 Oct 5.

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