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Items: 1 to 20 of 125

1.

Patient-derived organoid models help define personalized management of gastrointestinal cancer.

Aberle MR, Burkhart RA, Tiriac H, Olde Damink SWM, Dejong CHC, Tuveson DA, van Dam RM.

Br J Surg. 2018 Jan;105(2):e48-e60. doi: 10.1002/bjs.10726. Review.

2.

Circulating tumor cell-derived organoids: Current challenges and promises in medical research and precision medicine.

Praharaj PP, Bhutia SK, Nagrath S, Bitting RL, Deep G.

Biochim Biophys Acta Rev Cancer. 2018 Apr;1869(2):117-127. doi: 10.1016/j.bbcan.2017.12.005. Epub 2018 Jan 31. Review.

3.

Preserved genetic diversity in organoids cultured from biopsies of human colorectal cancer metastases.

Weeber F, van de Wetering M, Hoogstraat M, Dijkstra KK, Krijgsman O, Kuilman T, Gadellaa-van Hooijdonk CG, van der Velden DL, Peeper DS, Cuppen EP, Vries RG, Clevers H, Voest EE.

Proc Natl Acad Sci U S A. 2015 Oct 27;112(43):13308-11. doi: 10.1073/pnas.1516689112. Epub 2015 Oct 12.

4.

Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine.

Pauli C, Hopkins BD, Prandi D, Shaw R, Fedrizzi T, Sboner A, Sailer V, Augello M, Puca L, Rosati R, McNary TJ, Churakova Y, Cheung C, Triscott J, Pisapia D, Rao R, Mosquera JM, Robinson B, Faltas BM, Emerling BE, Gadi VK, Bernard B, Elemento O, Beltran H, Demichelis F, Kemp CJ, Grandori C, Cantley LC, Rubin MA.

Cancer Discov. 2017 May;7(5):462-477. doi: 10.1158/2159-8290.CD-16-1154. Epub 2017 Mar 22.

5.

Importance of organoids for personalized medicine.

Perkhofer L, Frappart PO, Müller M, Kleger A.

Per Med. 2018 Nov;15(6):461-465. doi: 10.2217/pme-2018-0071. Epub 2018 Nov 12. Review.

PMID:
30418092
6.

Stem cell-derived organoids and their application for medical research and patient treatment.

Bartfeld S, Clevers H.

J Mol Med (Berl). 2017 Jul;95(7):729-738. doi: 10.1007/s00109-017-1531-7. Epub 2017 Apr 8. Review.

PMID:
28391362
7.

Development of Patient-Derived Gastric Cancer Organoids from Endoscopic Biopsies and Surgical Tissues.

Gao M, Lin M, Rao M, Thompson H, Hirai K, Choi M, Georgakis GV, Sasson AR, Bucobo JC, Tzimas D, D'Souza LS, Buscaglia JM, Davis J, Shroyer KR, Li J, Powers S, Kim J.

Ann Surg Oncol. 2018 Sep;25(9):2767-2775. doi: 10.1245/s10434-018-6662-8. Epub 2018 Jul 12.

PMID:
30003451
8.

Personalized Cancer Medicine: An Organoid Approach.

Aboulkheyr Es H, Montazeri L, Aref AR, Vosough M, Baharvand H.

Trends Biotechnol. 2018 Apr;36(4):358-371. doi: 10.1016/j.tibtech.2017.12.005. Epub 2018 Jan 20. Review.

PMID:
29366522
9.

Organoid Culture of Isolated Cells from Patient-derived Tissues with Colorectal Cancer.

Xie BY, Wu AW.

Chin Med J (Engl). 2016 Oct 20;129(20):2469-2475. doi: 10.4103/0366-6999.191782.

10.

New tools for old drugs: Functional genetic screens to optimize current chemotherapy.

Gerhards NM, Rottenberg S.

Drug Resist Updat. 2018 Jan;36:30-46. doi: 10.1016/j.drup.2018.01.001. Epub 2018 Jan 12. Review.

11.

What role could organoids play in the personalization of cancer treatment?

Francies HE, Garnett MJ.

Pharmacogenomics. 2015;16(14):1523-6. doi: 10.2217/pgs.15.114. Epub 2015 Oct 20.

PMID:
26485224
12.

[Establishment of a living biobank : Improved guidance of precision cancer care with in vitro and in vivo cancer models].

Pauli C, Moch H, Rubin MA.

Pathologe. 2017 Nov;38(Suppl 2):160-168. doi: 10.1007/s00292-017-0346-1. Review. German.

PMID:
28956107
13.

Applications of Bioengineered 3D Tissue and Tumor Organoids in Drug Development and Precision Medicine: Current and Future.

Devarasetty M, Mazzocchi AR, Skardal A.

BioDrugs. 2018 Feb;32(1):53-68. doi: 10.1007/s40259-017-0258-x. Review.

PMID:
29383499
14.

Establishment of an organoid bank of biliary tract and pancreatic cancers and its application for personalized therapy and future treatment.

Saito Y.

J Gastroenterol Hepatol. 2019 Jul 1. doi: 10.1111/jgh.14773. [Epub ahead of print]

PMID:
31264257
15.

The potential of organoids in urological cancer research.

Wang S, Gao D, Chen Y.

Nat Rev Urol. 2017 Jul;14(7):401-414. doi: 10.1038/nrurol.2017.65. Epub 2017 May 23. Review.

16.

Organoid development in cancer genome discovery.

Gao D, Chen Y.

Curr Opin Genet Dev. 2015 Feb;30:42-8. doi: 10.1016/j.gde.2015.02.007. Epub 2015 Mar 19. Review.

17.

The Central Role of Wnt Signaling and Organoid Technology in Personalizing Anticancer Therapy.

Vincan E, Schwab RHM, Flanagan DJ, Moselen JM, Tran BM, Barker N, Phesse TJ.

Prog Mol Biol Transl Sci. 2018 Jan;153:299-319. doi: 10.1016/bs.pmbts.2017.11.009. Epub 2017 Dec 21. Review.

PMID:
29389521
18.

Organoid models of gastrointestinal Neoplasms: Origin, current status and future applications in personalized medicine.

Pan Y, Zhao S, Cao Z.

Genes Dis. 2018 Sep 24;5(4):323-330. doi: 10.1016/j.gendis.2018.09.002. eCollection 2018 Dec. Review.

19.

Assay Establishment and Validation of a High-Throughput Screening Platform for Three-Dimensional Patient-Derived Colon Cancer Organoid Cultures.

Boehnke K, Iversen PW, Schumacher D, Lallena MJ, Haro R, Amat J, Haybaeck J, Liebs S, Lange M, Schäfer R, Regenbrecht CR, Reinhard C, Velasco JA.

J Biomol Screen. 2016 Oct;21(9):931-41. doi: 10.1177/1087057116650965. Epub 2016 May 27.

20.

Use and application of 3D-organoid technology.

Artegiani B, Clevers H.

Hum Mol Genet. 2018 Aug 1;27(R2):R99-R107. doi: 10.1093/hmg/ddy187. Review.

PMID:
29796608

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