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Human airway branch variation and chronic obstructive pulmonary disease.

Smith BM, Traboulsi H, Austin JHM, Manichaikul A, Hoffman EA, Bleecker ER, Cardoso WV, Cooper C, Couper DJ, Dashnaw SM, Guo J, Han MK, Hansel NN, Hughes EW, Jacobs DR Jr, Kanner RE, Kaufman JD, Kleerup E, Lin CL, Liu K, Lo Cascio CM, Martinez FJ, Nguyen JN, Prince MR, Rennard S, Rich SS, Simon L, Sun Y, Watson KE, Woodruff PG, Baglole CJ, Barr RG; MESA Lung and SPIROMICS investigators.

Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):E974-E981. doi: 10.1073/pnas.1715564115. Epub 2018 Jan 16.


CT scanning-based phenotypes vary with ADRB2 polymorphisms in chronic obstructive pulmonary disease.

Kim WJ, Oh YM, Sung J, Lee YK, Seo JB, Kim N, Kim TH, Huh JW, Lee JH, Kim EK, Lee JH, Lee SM, Lee S, Lim SY, Shin TR, Yoon HI, Kwon SY, Lee SD.

Respir Med. 2009 Jan;103(1):98-103. doi: 10.1016/j.rmed.2008.07.025. Epub 2008 Sep 11.


Is intrathoracic tracheal collapsibility correlated to clinical phenotypes and sex in patients with COPD?

Camiciottoli G, Diciotti S, Bigazzi F, Lombardo S, Bartolucci M, Paoletti M, Mascalchi M, Pistolesi M.

Int J Chron Obstruct Pulmon Dis. 2015 Apr 28;10:843-52. doi: 10.2147/COPD.S80558. eCollection 2015.


Estimation of the site of wheezes in pulmonary emphysema: airflow simulation study by the use of A 4D lung model.

Kitaoka H, Cok S.

Conf Proc IEEE Eng Med Biol Soc. 2013;2013:449-52. doi: 10.1109/EMBC.2013.6609533.


Relative contributions of emphysema and airway remodelling to airflow limitation in COPD: Consistent results from two cohorts.

Tho NV, Ryujin Y, Ogawa E, Trang le TH, Kanda R, Goto K, Yamaguchi M, Nagao T, Lan le TT, Nakano Y.

Respirology. 2015 May;20(4):594-601. doi: 10.1111/resp.12505. Epub 2015 Mar 18.


Comparison of endobronchial ultrasound and high resolution computed tomography as tools for airway wall imaging in asthma and chronic obstructive pulmonary disease.

Gorska K, Korczynski P, Mierzejewski M, Kosciuch J, Zukowska M, Maskey-Warzechowska M, Krenke R.

Respir Med. 2016 Aug;117:131-8. doi: 10.1016/j.rmed.2016.06.011. Epub 2016 Jun 9.


Contribution of CT quantified emphysema, air trapping and airway wall thickness on pulmonary function in male smokers with and without COPD.

Mohamed Hoesein FA, de Jong PA, Lammers JW, Mali WP, Mets OM, Schmidt M, de Koning HJ, Aalst Cv, Oudkerk M, Vliegenthart R, Ginneken Bv, van Rikxoort EM, Zanen P.

COPD. 2014 Sep;11(5):503-9. doi: 10.3109/15412555.2014.933952. Epub 2014 Aug 5.


Changes in the airway lumen and surrounding parenchyma in chronic obstructive pulmonary disease.

Kurashima K, Hoshi T, Takaku Y, Kanauchi T, Nakamoto K, Ueda M, Takayanagi N, Colby TV, Sugita Y, Kawabata Y.

Int J Chron Obstruct Pulmon Dis. 2013;8:523-32. doi: 10.2147/COPD.S52637. Epub 2013 Oct 30.


Relationship Between Emphysema Severity and the Location of Lung Cancer in Patients With Chronic Obstructive Lung Disease.

Lim J, Shin KM, Lee K, Lim JK, Kim HJ, Cho SH, Cha SI.

AJR Am J Roentgenol. 2015 Sep;205(3):540-5. doi: 10.2214/AJR.14.13992.


Transforming growth factor-beta receptor-3 is associated with pulmonary emphysema.

Hersh CP, Hansel NN, Barnes KC, Lomas DA, Pillai SG, Coxson HO, Mathias RA, Rafaels NM, Wise RA, Connett JE, Klanderman BJ, Jacobson FL, Gill R, Litonjua AA, Sparrow D, Reilly JJ, Silverman EK; ICGN Investigators.

Am J Respir Cell Mol Biol. 2009 Sep;41(3):324-31. doi: 10.1165/rcmb.2008-0427OC. Epub 2009 Jan 8.


The 15q24/25 susceptibility variant for lung cancer and chronic obstructive pulmonary disease is associated with emphysema.

Lambrechts D, Buysschaert I, Zanen P, Coolen J, Lays N, Cuppens H, Groen HJ, Dewever W, van Klaveren RJ, Verschakelen J, Wijmenga C, Postma DS, Decramer M, Janssens W.

Am J Respir Crit Care Med. 2010 Mar 1;181(5):486-93. doi: 10.1164/rccm.200909-1364OC. Epub 2009 Dec 10.


Quantitative computed tomography measurements to evaluate airway disease in chronic obstructive pulmonary disease: Relationship to physiological measurements, clinical index and visual assessment of airway disease.

Nambu A, Zach J, Schroeder J, Jin G, Kim SS, Kim YI, Schnell C, Bowler R, Lynch DA.

Eur J Radiol. 2016 Nov;85(11):2144-2151. doi: 10.1016/j.ejrad.2016.09.010. Epub 2016 Sep 13. Review.


Polymorphisms in the superoxide dismutase-3 gene are associated with emphysema in COPD.

Sørheim IC, DeMeo DL, Washko G, Litonjua A, Sparrow D, Bowler R, Bakke P, Pillai SG, Coxson HO, Lomas DA, Silverman EK, Hersh CP; International COPD Genetics Network Investigators.

COPD. 2010 Aug;7(4):262-8. doi: 10.3109/15412555.2010.496821.


Airway dimensions and pulmonary function in chronic obstructive pulmonary disease and bronchial asthma.

Kurashima K, Hoshi T, Takayanagi N, Takaku Y, Kagiyama N, Ohta C, Fujimura M, Sugita Y.

Respirology. 2012 Jan;17(1):79-86. doi: 10.1111/j.1440-1843.2011.02052.x.


Epidemiology, radiology, and genetics of nicotine dependence in COPD.

Kim DK, Hersh CP, Washko GR, Hokanson JE, Lynch DA, Newell JD, Murphy JR, Crapo JD, Silverman EK; COPD Gene Investigators.

Respir Res. 2011 Jan 13;12:9. doi: 10.1186/1465-9921-12-9.


Airway wall thickening and emphysema show independent familial aggregation in chronic obstructive pulmonary disease.

Patel BD, Coxson HO, Pillai SG, Agustí AG, Calverley PM, Donner CF, Make BJ, Müller NL, Rennard SI, Vestbo J, Wouters EF, Hiorns MP, Nakano Y, Camp PG, Nasute Fauerbach PV, Screaton NJ, Campbell EJ, Anderson WH, Paré PD, Levy RD, Lake SL, Silverman EK, Lomas DA; International COPD Genetics Network.

Am J Respir Crit Care Med. 2008 Sep 1;178(5):500-5. doi: 10.1164/rccm.200801-059OC. Epub 2008 Jun 19.


A mixed phenotype of airway wall thickening and emphysema is associated with dyspnea and hospitalization for chronic obstructive pulmonary disease.

Van Tho N, Ogawa E, Trang le TH, Ryujin Y, Kanda R, Nakagawa H, Goto K, Fukunaga K, Higami Y, Seto R, Wada H, Yamaguchi M, Nagao T, Lan le TT, Nakano Y.

Ann Am Thorac Soc. 2015 Jul;12(7):988-96. doi: 10.1513/AnnalsATS.201411-501OC.


Genetic predisposition to chronic obstructive pulmonary disease and/or lung cancer: important considerations when evaluating risk.

El-Zein RA, Young RP, Hopkins RJ, Etzel CJ.

Cancer Prev Res (Phila). 2012 Apr;5(4):522-7. doi: 10.1158/1940-6207.CAPR-12-0042. Review.


Two CHRN susceptibility variants for COPD are genetic determinants of emphysema and chest computed tomography manifestations in Chinese patients.

Zhao Z, Jiang C, Zhao D, Li Y, Liang C, Liu W, Wei S, Zhou Y, Zhao Z, Ran P.

Int J Chron Obstruct Pulmon Dis. 2017 May 15;12:1447-1455. doi: 10.2147/COPD.S134010. eCollection 2017.


Relationships between airflow obstruction and quantitative CT measurements of emphysema, air trapping, and airways in subjects with and without chronic obstructive pulmonary disease.

Schroeder JD, McKenzie AS, Zach JA, Wilson CG, Curran-Everett D, Stinson DS, Newell JD Jr, Lynch DA.

AJR Am J Roentgenol. 2013 Sep;201(3):W460-70. doi: 10.2214/AJR.12.10102.

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