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Arctic berry extracts target the gut-liver axis to alleviate metabolic endotoxaemia, insulin resistance and hepatic steatosis in diet-induced obese mice.

Anhê FF, Varin TV, Le Barz M, Pilon G, Dudonné S, Trottier J, St-Pierre P, Harris CS, Lucas M, Lemire M, Dewailly É, Barbier O, Desjardins Y, Roy D, Marette A.

Diabetologia. 2018 Apr;61(4):919-931. doi: 10.1007/s00125-017-4520-z. Epub 2017 Dec 21.


A polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increased Akkermansia spp. population in the gut microbiota of mice.

Anhê FF, Roy D, Pilon G, Dudonné S, Matamoros S, Varin TV, Garofalo C, Moine Q, Desjardins Y, Levy E, Marette A.

Gut. 2015 Jun;64(6):872-83. doi: 10.1136/gutjnl-2014-307142. Epub 2014 Jul 30.


A polyphenol-rich cranberry extract reverses insulin resistance and hepatic steatosis independently of body weight loss.

Anhê FF, Nachbar RT, Varin TV, Vilela V, Dudonné S, Pilon G, Fournier M, Lecours MA, Desjardins Y, Roy D, Levy E, Marette A.

Mol Metab. 2017 Dec;6(12):1563-1573. doi: 10.1016/j.molmet.2017.10.003. Epub 2017 Oct 18.


Supplementation with Vitis vinifera L. skin extract improves insulin resistance and prevents hepatic lipid accumulation and steatosis in high-fat diet-fed mice.

Santos IB, de Bem GF, Cordeiro VSC, da Costa CA, de Carvalho LCRM, da Rocha APM, da Costa GF, Ognibene DT, de Moura RS, Resende AC.

Nutr Res. 2017 Jul;43:69-81. doi: 10.1016/j.nutres.2017.05.007. Epub 2017 May 18.


Red pitaya betacyanins protects from diet-induced obesity, liver steatosis and insulin resistance in association with modulation of gut microbiota in mice.

Song H, Chu Q, Yan F, Yang Y, Han W, Zheng X.

J Gastroenterol Hepatol. 2016 Aug;31(8):1462-9. doi: 10.1111/jgh.13278.


Mulberry ethanol extract attenuates hepatic steatosis and insulin resistance in high-fat diet-fed mice.

Song H, Lai J, Tang Q, Zheng X.

Nutr Res. 2016 Jul;36(7):710-8. doi: 10.1016/j.nutres.2016.01.011. Epub 2016 Feb 2.


Treatment with camu camu (Myrciaria dubia) prevents obesity by altering the gut microbiota and increasing energy expenditure in diet-induced obese mice.

Anhê FF, Nachbar RT, Varin TV, Trottier J, Dudonné S, Le Barz M, Feutry P, Pilon G, Barbier O, Desjardins Y, Roy D, Marette A.

Gut. 2018 Jul 31. pii: gutjnl-2017-315565. doi: 10.1136/gutjnl-2017-315565. [Epub ahead of print]


Chlorogenic acid improves high fat diet-induced hepatic steatosis and insulin resistance in mice.

Ma Y, Gao M, Liu D.

Pharm Res. 2015 Apr;32(4):1200-9. doi: 10.1007/s11095-014-1526-9. Epub 2014 Sep 24.


Dietary capsaicin reduces obesity-induced insulin resistance and hepatic steatosis in obese mice fed a high-fat diet.

Kang JH, Goto T, Han IS, Kawada T, Kim YM, Yu R.

Obesity (Silver Spring). 2010 Apr;18(4):780-7. doi: 10.1038/oby.2009.301. Epub 2009 Oct 1.


Parkinsonia aculeata (Caesalpineaceae) improves high-fat diet-induced insulin resistance in mice through the enhancement of insulin signaling and mitochondrial biogenesis.

Araújo TG, de Oliveira AG, Vecina JF, Marin RM, Franco ES, Abdalla Saad MJ, de Sousa Maia MB.

J Ethnopharmacol. 2016 May 13;183:95-102. doi: 10.1016/j.jep.2016.02.048. Epub 2016 Mar 3.


Adipose tissue, liver and pancreas structural alterations in C57BL/6 mice fed high-fat-high-sucrose diet supplemented with fish oil (n-3 fatty acid rich oil).

Nascimento FA, Barbosa-da-Silva S, Fernandes-Santos C, Mandarim-de-Lacerda CA, Aguila MB.

Exp Toxicol Pathol. 2010 Jan;62(1):17-25. doi: 10.1016/j.etp.2008.12.008. Epub 2009 Jan 30.


Effects of octreotide on hepatic glycogenesis in rats with high fat diet‑induced obesity.

Wang XX, Ye T, Li M, Li X, Qiang O, Tang CW, Liu R.

Mol Med Rep. 2017 Jul;16(1):109-118. doi: 10.3892/mmr.2017.6586. Epub 2017 May 16.


Bardoxolone methyl prevents insulin resistance and the development of hepatic steatosis in mice fed a high-fat diet.

Camer D, Yu Y, Szabo A, Dinh CH, Wang H, Cheng L, Huang XF.

Mol Cell Endocrinol. 2015 Sep 5;412:36-43. doi: 10.1016/j.mce.2015.05.018. Epub 2015 May 19.


The beneficial potential of polyphenol-enriched fraction from Erigerontis Herba on metabolic syndrome.

Wang YP, Wat E, Koon CM, Wong CW, Cheung DW, Leung PC, Zhao QS, Fung KP, Lau CB.

J Ethnopharmacol. 2016 Jul 1;187:94-103. doi: 10.1016/j.jep.2016.04.040. Epub 2016 Apr 25.


An increase in the Akkermansia spp. population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice.

Shin NR, Lee JC, Lee HY, Kim MS, Whon TW, Lee MS, Bae JW.

Gut. 2014 May;63(5):727-35. doi: 10.1136/gutjnl-2012-303839. Epub 2013 Jun 26.


Chardonnay Grape Seed Flour Ameliorates Hepatic Steatosis and Insulin Resistance via Altered Hepatic Gene Expression for Oxidative Stress, Inflammation, and Lipid and Ceramide Synthesis in Diet-Induced Obese Mice.

Seo KH, Bartley GE, Tam C, Kim HS, Kim DH, Chon JW, Kim H, Yokoyama W.

PLoS One. 2016 Dec 15;11(12):e0167680. doi: 10.1371/journal.pone.0167680. eCollection 2016.


Labrador tea (Rhododendron groenlandicum) attenuates insulin resistance in a diet-induced obesity mouse model.

Ouchfoun M, Eid HM, Musallam L, Brault A, Li S, Vallerand D, Arnason JT, Haddad PS.

Eur J Nutr. 2016 Apr;55(3):941-54. doi: 10.1007/s00394-015-0908-z. Epub 2015 Apr 28.


Fish oil and argan oil intake differently modulate insulin resistance and glucose intolerance in a rat model of dietary-induced obesity.

Samane S, Christon R, Dombrowski L, Turcotte S, Charrouf Z, Lavigne C, Levy E, Bachelard H, Amarouch H, Marette A, Haddad PS.

Metabolism. 2009 Jul;58(7):909-19. doi: 10.1016/j.metabol.2009.02.013.


Gut carbohydrate metabolism instead of fat metabolism regulated by gut microbes mediates high-fat diet-induced obesity.

Li M, Gu D, Xu N, Lei F, Du L, Zhang Y, Xie W.

Benef Microbes. 2014 Sep;5(3):335-44. doi: 10.3920/BM2013.0071.


Blueberry Supplementation Influences the Gut Microbiota, Inflammation, and Insulin Resistance in High-Fat-Diet-Fed Rats.

Lee S, Keirsey KI, Kirkland R, Grunewald ZI, Fischer JG, de La Serre CB.

J Nutr. 2018 Feb 1;148(2):209-219. doi: 10.1093/jn/nxx027.

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