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Items: 1 to 20 of 122

1.

Pilot study demonstrating metabolic and anti-proliferative effects of in vivo anti-oxidant supplementation with N-Acetylcysteine in Breast Cancer.

Monti D, Sotgia F, Whitaker-Menezes D, Tuluc M, Birbe R, Berger A, Lazar M, Cotzia P, Draganova-Tacheva R, Lin Z, Domingo-Vidal M, Newberg A, Lisanti MP, Martinez-Outschoorn U.

Semin Oncol. 2017 Jun;44(3):226-232. doi: 10.1053/j.seminoncol.2017.10.001. Epub 2017 Oct 10.

2.

BRCA1 mutations drive oxidative stress and glycolysis in the tumor microenvironment: implications for breast cancer prevention with antioxidant therapies.

Martinez-Outschoorn UE, Balliet R, Lin Z, Whitaker-Menezes D, Birbe RC, Bombonati A, Pavlides S, Lamb R, Sneddon S, Howell A, Sotgia F, Lisanti MP.

Cell Cycle. 2012 Dec 1;11(23):4402-13. doi: 10.4161/cc.22776. Epub 2012 Nov 21.

3.

Oncogenes and inflammation rewire host energy metabolism in the tumor microenvironment: RAS and NFκB target stromal MCT4.

Martinez-Outschoorn UE, Curry JM, Ko YH, Lin Z, Tuluc M, Cognetti D, Birbe RC, Pribitkin E, Bombonati A, Pestell RG, Howell A, Sotgia F, Lisanti MP.

Cell Cycle. 2013 Aug 15;12(16):2580-97. doi: 10.4161/cc.25510. Epub 2013 Jul 8.

4.

Using the "reverse Warburg effect" to identify high-risk breast cancer patients: stromal MCT4 predicts poor clinical outcome in triple-negative breast cancers.

Witkiewicz AK, Whitaker-Menezes D, Dasgupta A, Philp NJ, Lin Z, Gandara R, Sneddon S, Martinez-Outschoorn UE, Sotgia F, Lisanti MP.

Cell Cycle. 2012 Mar 15;11(6):1108-17. doi: 10.4161/cc.11.6.19530. Epub 2012 Mar 15.

5.

Tumor microenvironment and metabolic synergy in breast cancers: critical importance of mitochondrial fuels and function.

Martinez-Outschoorn U, Sotgia F, Lisanti MP.

Semin Oncol. 2014 Apr;41(2):195-216. doi: 10.1053/j.seminoncol.2014.03.002. Epub 2014 Mar 5. Review.

PMID:
24787293
6.

Cancer metabolism, stemness and tumor recurrence: MCT1 and MCT4 are functional biomarkers of metabolic symbiosis in head and neck cancer.

Curry JM, Tuluc M, Whitaker-Menezes D, Ames JA, Anantharaman A, Butera A, Leiby B, Cognetti DM, Sotgia F, Lisanti MP, Martinez-Outschoorn UE.

Cell Cycle. 2013 May 1;12(9):1371-84. doi: 10.4161/cc.24092. Epub 2013 Apr 10.

7.

Loss of caveolin-1 and gain of MCT4 expression in the tumor stroma: key events in the progression from an in situ to an invasive breast carcinoma.

Martins D, Beça FF, Sousa B, Baltazar F, Paredes J, Schmitt F.

Cell Cycle. 2013 Aug 15;12(16):2684-90. doi: 10.4161/cc.25794. Epub 2013 Jul 29.

8.

Hodgkin lymphoma: A complex metabolic ecosystem with glycolytic reprogramming of the tumor microenvironment.

Mikkilineni L, Whitaker-Menezes D, Domingo-Vidal M, Sprandio J, Avena P, Cotzia P, Dulau-Florea A, Gong J, Uppal G, Zhan T, Leiby B, Lin Z, Pro B, Sotgia F, Lisanti MP, Martinez-Outschoorn U.

Semin Oncol. 2017 Jun;44(3):218-225. doi: 10.1053/j.seminoncol.2017.10.003. Epub 2017 Oct 10.

9.

Evidence for a stromal-epithelial "lactate shuttle" in human tumors: MCT4 is a marker of oxidative stress in cancer-associated fibroblasts.

Whitaker-Menezes D, Martinez-Outschoorn UE, Lin Z, Ertel A, Flomenberg N, Witkiewicz AK, Birbe RC, Howell A, Pavlides S, Gandara R, Pestell RG, Sotgia F, Philp NJ, Lisanti MP.

Cell Cycle. 2011 Jun 1;10(11):1772-83. Epub 2011 Jun 1.

10.

MRI staging after neoadjuvant chemotherapy for breast cancer: does tumor biology affect accuracy?

McGuire KP, Toro-Burguete J, Dang H, Young J, Soran A, Zuley M, Bhargava R, Bonaventura M, Johnson R, Ahrendt G.

Ann Surg Oncol. 2011 Oct;18(11):3149-54. doi: 10.1245/s10434-011-1912-z. Epub 2011 Sep 27.

PMID:
21947592
11.

Metformin effects on head and neck squamous carcinoma microenvironment: Window of opportunity trial.

Curry J, Johnson J, Tassone P, Vidal MD, Menezes DW, Sprandio J, Mollaee M, Cotzia P, Birbe R, Lin Z, Gill K, Duddy E, Zhan T, Leiby B, Reyzer M, Cognetti D, Luginbuhl A, Tuluc M, Martinez-Outschoorn U.

Laryngoscope. 2017 Aug;127(8):1808-1815. doi: 10.1002/lary.26489. Epub 2017 Feb 10.

12.

Impact of biomarker changes during neoadjuvant chemotherapy for clinical response in patients with residual breast cancers.

Enomoto Y, Morimoto T, Nishimukai A, Higuchi T, Yanai A, Miyagawa Y, Murase K, Imamura M, Takatsuka Y, Nomura T, Takeda M, Watanabe T, Hirota S, Miyoshi Y.

Int J Clin Oncol. 2016 Apr;21(2):254-261. doi: 10.1007/s10147-015-0897-1. Epub 2015 Sep 4.

PMID:
26338270
13.

Metformin Effects on Metabolic Coupling and Tumor Growth in Oral Cavity Squamous Cell Carcinoma Coinjection Xenografts.

Tassone P, Domingo-Vidal M, Whitaker-Menezes D, Lin Z, Roche M, Tuluc M, Martinez-Outschoorn U, Curry J.

Otolaryngol Head Neck Surg. 2018 May;158(5):867-877. doi: 10.1177/0194599817746934. Epub 2017 Dec 12.

PMID:
29232177
14.

Ethanol exposure induces the cancer-associated fibroblast phenotype and lethal tumor metabolism: implications for breast cancer prevention.

Sanchez-Alvarez R, Martinez-Outschoorn UE, Lin Z, Lamb R, Hulit J, Howell A, Sotgia F, Rubin E, Lisanti MP.

Cell Cycle. 2013 Jan 15;12(2):289-301. doi: 10.4161/cc.23109. Epub 2012 Jan 15.

15.

The impact of caveolin protein expression in tumor stroma on prognosis of breast cancer.

Koo JS, Park S, Kim SI, Lee S, Park BW.

Tumour Biol. 2011 Aug;32(4):787-99. doi: 10.1007/s13277-011-0181-6. Epub 2011 May 17.

PMID:
21584795
16.
17.

Histopathologic correlation of residual mammographic microcalcifications after neoadjuvant chemotherapy for locally advanced breast cancer.

Adrada BE, Huo L, Lane DL, Arribas EM, Resetkova E, Yang W.

Ann Surg Oncol. 2015 Apr;22(4):1111-7. doi: 10.1245/s10434-014-4113-8. Epub 2014 Oct 7.

PMID:
25287438
18.

Metabolic coupling and the Reverse Warburg Effect in cancer: Implications for novel biomarker and anticancer agent development.

Wilde L, Roche M, Domingo-Vidal M, Tanson K, Philp N, Curry J, Martinez-Outschoorn U.

Semin Oncol. 2017 Jun;44(3):198-203. doi: 10.1053/j.seminoncol.2017.10.004. Epub 2017 Oct 10. Review.

19.

[Primary systemic therapy in breast cancer patients (2007-2010)].

Zapf I, Tizedes G, Pavlovics G, Kovács G, Kálmán E, Szalai G, Kövér E, Farkas R, Horváth OP.

Magy Seb. 2011 Oct;64(5):223-8. doi: 10.1556/MaSeb.64.2011.5.1. Hungarian.

PMID:
21997525
20.

Mitochondrial and glycolytic metabolic compartmentalization in diffuse large B-cell lymphoma.

Gooptu M, Whitaker-Menezes D, Sprandio J, Domingo-Vidal M, Lin Z, Uppal G, Gong J, Fratamico R, Leiby B, Dulau-Florea A, Caro J, Martinez-Outschoorn U.

Semin Oncol. 2017 Jun;44(3):204-217. doi: 10.1053/j.seminoncol.2017.10.002. Epub 2017 Oct 10.

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