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Items: 1 to 20 of 102

1.

Structural and functional analysis of an OB-fold in human Ctc1 implicated in telomere maintenance and bone marrow syndromes.

Shastrula PK, Rice CT, Wang Z, Lieberman PM, Skordalakes E.

Nucleic Acids Res. 2018 Jan 25;46(2):972-984. doi: 10.1093/nar/gkx1213.

2.

CTC1-STN1 terminates telomerase while STN1-TEN1 enables C-strand synthesis during telomere replication in colon cancer cells.

Feng X, Hsu SJ, Bhattacharjee A, Wang Y, Diao J, Price CM.

Nat Commun. 2018 Jul 19;9(1):2827. doi: 10.1038/s41467-018-05154-z.

3.

Human TEN1 maintains telomere integrity and functions in genome-wide replication restart.

Kasbek C, Wang F, Price CM.

J Biol Chem. 2013 Oct 18;288(42):30139-50. doi: 10.1074/jbc.M113.493478. Epub 2013 Sep 11.

4.

CTC1-mediated C-strand fill-in is an essential step in telomere length maintenance.

Feng X, Hsu SJ, Kasbek C, Chaiken M, Price CM.

Nucleic Acids Res. 2017 May 5;45(8):4281-4293. doi: 10.1093/nar/gkx125.

5.

CTC1-STN1 coordinates G- and C-strand synthesis to regulate telomere length.

Gu P, Jia S, Takasugi T, Smith E, Nandakumar J, Hendrickson E, Chang S.

Aging Cell. 2018 Aug;17(4):e12783. doi: 10.1111/acel.12783. Epub 2018 May 17.

6.

POT1a and components of CST engage telomerase and regulate its activity in Arabidopsis.

Renfrew KB, Song X, Lee JR, Arora A, Shippen DE.

PLoS Genet. 2014 Oct 16;10(10):e1004738. doi: 10.1371/journal.pgen.1004738. eCollection 2014 Oct.

7.

The fission yeast Stn1-Ten1 complex limits telomerase activity via its SUMO-interacting motif and promotes telomeres replication.

Matmati S, Vaurs M, Escandell JM, Maestroni L, Nakamura TM, Ferreira MG, Géli V, Coulon S.

Sci Adv. 2018 May 16;4(5):eaar2740. doi: 10.1126/sciadv.aar2740. eCollection 2018 May.

8.

Protection of telomeres by a conserved Stn1-Ten1 complex.

Martín V, Du LL, Rozenzhak S, Russell P.

Proc Natl Acad Sci U S A. 2007 Aug 28;104(35):14038-43. Epub 2007 Aug 22.

9.

MERISTEM DISORGANIZATION1 encodes TEN1, an essential telomere protein that modulates telomerase processivity in Arabidopsis.

Leehy KA, Lee JR, Song X, Renfrew KB, Shippen DE.

Plant Cell. 2013 Apr;25(4):1343-54. doi: 10.1105/tpc.112.107425. Epub 2013 Apr 9.

10.

The human CTC1/STN1/TEN1 complex regulates telomere maintenance in ALT cancer cells.

Huang C, Jia P, Chastain M, Shiva O, Chai W.

Exp Cell Res. 2017 Jun 15;355(2):95-104. doi: 10.1016/j.yexcr.2017.03.058. Epub 2017 Mar 31.

11.

CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustion.

Gu P, Min JN, Wang Y, Huang C, Peng T, Chai W, Chang S.

EMBO J. 2012 May 16;31(10):2309-21. doi: 10.1038/emboj.2012.96. Epub 2012 Apr 24.

12.

Stn1-Ten1 is an Rpa2-Rpa3-like complex at telomeres.

Sun J, Yu EY, Yang Y, Confer LA, Sun SH, Wan K, Lue NF, Lei M.

Genes Dev. 2009 Dec 15;23(24):2900-14. doi: 10.1101/gad.1851909.

13.

RPA-like mammalian Ctc1-Stn1-Ten1 complex binds to single-stranded DNA and protects telomeres independently of the Pot1 pathway.

Miyake Y, Nakamura M, Nabetani A, Shimamura S, Tamura M, Yonehara S, Saito M, Ishikawa F.

Mol Cell. 2009 Oct 23;36(2):193-206. doi: 10.1016/j.molcel.2009.08.009.

14.

Molecular basis of telomere syndrome caused by CTC1 mutations.

Chen LY, Majerská J, Lingner J.

Genes Dev. 2013 Oct 1;27(19):2099-108. doi: 10.1101/gad.222893.113.

15.

Ssu72 phosphatase is a conserved telomere replication terminator.

Escandell JM, Carvalho ES, Gallo-Fernandez M, Reis CC, Matmati S, Luís IM, Abreu IA, Coulon S, Ferreira MG.

EMBO J. 2019 Apr 1;38(7). pii: e100476. doi: 10.15252/embj.2018100476. Epub 2019 Feb 21.

16.

Tpz1TPP1 SUMOylation reveals evolutionary conservation of SUMO-dependent Stn1 telomere association.

Garg M, Gurung RL, Mansoubi S, Ahmed JO, Davé A, Watts FZ, Bianchi A.

EMBO Rep. 2014 Aug;15(8):871-7. doi: 10.15252/embr.201438919. Epub 2014 Jun 12.

17.

Structure of the human telomeric Stn1-Ten1 capping complex.

Bryan C, Rice C, Harkisheimer M, Schultz DC, Skordalakes E.

PLoS One. 2013 Jun 24;8(6):e66756. doi: 10.1371/journal.pone.0066756. Print 2013.

18.
19.

STN1 OB Fold Mutation Alters DNA Binding and Affects Selective Aspects of CST Function.

Bhattacharjee A, Stewart J, Chaiken M, Price CM.

PLoS Genet. 2016 Sep 30;12(9):e1006342. doi: 10.1371/journal.pgen.1006342. eCollection 2016 Sep.

20.

Human CST has independent functions during telomere duplex replication and C-strand fill-in.

Wang F, Stewart JA, Kasbek C, Zhao Y, Wright WE, Price CM.

Cell Rep. 2012 Nov 29;2(5):1096-103. doi: 10.1016/j.celrep.2012.10.007. Epub 2012 Nov 8.

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