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Items: 1 to 20 of 78

1.

Protein activation mapping of human sun-protected epidermis after an acute dose of erythemic solar simulated light.

Einspahr JG, Curiel-Lewandrowski C, Calvert VS, Stratton SP, Alberts DS, Warneke J, Hu C, Saboda K, Wagener EL, Dickinson S, Dong Z, Bode AM, PetricoinIII EF.

NPJ Precis Oncol. 2017;1. pii: 34. doi: 10.1038/s41698-017-0037-7. Epub 2017 Sep 21.

2.

Activation of the PI3K/Akt/mTOR and MAPK Signaling Pathways in Response to Acute Solar-Simulated Light Exposure of Human Skin.

Bermudez Y, Stratton SP, Curiel-Lewandrowski C, Warneke J, Hu C, Bowden GT, Dickinson SE, Dong Z, Bode AM, Saboda K, Brooks CA, Petricoin EF 3rd, Hurst CA, Alberts DS, Einspahr JG.

Cancer Prev Res (Phila). 2015 Aug;8(8):720-8. doi: 10.1158/1940-6207.CAPR-14-0407. Epub 2015 Jun 1.

4.

PI-103 and sorafenib inhibit hepatocellular carcinoma cell proliferation by blocking Ras/Raf/MAPK and PI3K/AKT/mTOR pathways.

Gedaly R, Angulo P, Hundley J, Daily MF, Chen C, Koch A, Evers BM.

Anticancer Res. 2010 Dec;30(12):4951-8.

5.

Fyn is a redox sensor involved in solar ultraviolet light-induced signal transduction in skin carcinogenesis.

Kim JE, Roh E, Lee MH, Yu DH, Kim DJ, Lim TG, Jung SK, Peng C, Cho YY, Dickinson S, Alberts D, Bowden GT, Einspahr J, Stratton SP, Curiel-Lewandrowski C, Bode AM, Lee KW, Dong Z.

Oncogene. 2016 Aug 4;35(31):4091-101. doi: 10.1038/onc.2015.471. Epub 2015 Dec 21.

6.

PKI-587 and sorafenib targeting PI3K/AKT/mTOR and Ras/Raf/MAPK pathways synergistically inhibit HCC cell proliferation.

Gedaly R, Angulo P, Hundley J, Daily MF, Chen C, Evers BM.

J Surg Res. 2012 Aug;176(2):542-8. doi: 10.1016/j.jss.2011.10.045. Epub 2011 Nov 21.

PMID:
22261591
7.

Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance.

McCubrey JA, Steelman LS, Abrams SL, Lee JT, Chang F, Bertrand FE, Navolanic PM, Terrian DM, Franklin RA, D'Assoro AB, Salisbury JL, Mazzarino MC, Stivala F, Libra M.

Adv Enzyme Regul. 2006;46:249-79. Epub 2006 Jul 18.

PMID:
16854453
8.

Genetic ablation of caspase-7 promotes solar-simulated light-induced mouse skin carcinogenesis: the involvement of keratin-17.

Lee MH, Lim DY, Kim MO, Lee SY, Shin SH, Kim JY, Kim SH, Kim DJ, Jung SK, Yao K, Kundu JK, Lee HS, Lee CJ, Dickinson SE, Alberts D, Bowden GT, Stratton S, Curiel C, Einspahr J, Bode AM, Surh YJ, Cho YY, Dong Z.

Carcinogenesis. 2015 Nov;36(11):1372-80. doi: 10.1093/carcin/bgv110. Epub 2015 Aug 12.

9.

Functional protein pathway activation mapping of the progression of normal skin to squamous cell carcinoma.

Einspahr JG, Calvert V, Alberts DS, Curiel-Lewandrowski C, Warneke J, Krouse R, Stratton SP, Liotta L, Longo C, Pellacani G, Prasad A, Sagerman P, Bermudez Y, Deng J, Bowden GT, Petricoin EF 3rd.

Cancer Prev Res (Phila). 2012 Mar;5(3):403-13. doi: 10.1158/1940-6207.CAPR-11-0427. Erratum in: Cancer Prev Res (Phila). 2012 Aug;5(8):1072. Pellicani, Giovanni [corrected to Pellacani, Giovanni].

10.

Photocarcinogenesis study of aloe vera [CAS NO. 481-72-1(Aloe-emodin)] in SKH-1 mice (simulated solar light and topical application study).

National Toxicology Program.

Natl Toxicol Program Tech Rep Ser. 2010 Sep;(553):7-33, 35-97, 99-103 passim.

11.

Synthetic lethal interaction between PI3K/Akt/mTOR and Ras/MEK/ERK pathway inhibition in rhabdomyosarcoma.

Guenther MK, Graab U, Fulda S.

Cancer Lett. 2013 Sep 1;337(2):200-9. doi: 10.1016/j.canlet.2013.05.010. Epub 2013 May 16.

PMID:
23684925
12.

Ultraviolet irradiation alters transforming growth factor beta/smad pathway in human skin in vivo.

Quan T, He T, Kang S, Voorhees JJ, Fisher GJ.

J Invest Dermatol. 2002 Aug;119(2):499-506.

13.

Aldosterone-induced mesangial cell proliferation is mediated by EGF receptor transactivation.

Huang S, Zhang A, Ding G, Chen R.

Am J Physiol Renal Physiol. 2009 Jun;296(6):F1323-33. doi: 10.1152/ajprenal.90428.2008. Epub 2009 Apr 1.

14.

Inhibition of Akt Enhances the Chemopreventive Effects of Topical Rapamycin in Mouse Skin.

Dickinson SE, Janda J, Criswell J, Blohm-Mangone K, Olson ER, Liu Z, Barber C, Petricoin EF 3rd, Calvert VS, Einspahr J, Dickinson JE, Stratton SP, Curiel-Lewandrowski C, Saboda K, Hu C, Bode AM, Dong Z, Alberts DS, Timothy Bowden G.

Cancer Prev Res (Phila). 2016 Mar;9(3):215-24. doi: 10.1158/1940-6207.CAPR-15-0419. Epub 2016 Jan 22.

15.

Targeting the PI3K/AKT/mTOR and Raf/MEK/ERK pathways in the treatment of breast cancer.

Saini KS, Loi S, de Azambuja E, Metzger-Filho O, Saini ML, Ignatiadis M, Dancey JE, Piccart-Gebhart MJ.

Cancer Treat Rev. 2013 Dec;39(8):935-46. doi: 10.1016/j.ctrv.2013.03.009. Epub 2013 May 3.

PMID:
23643661
16.

The PI3K/Akt and mTOR/P70S6K signaling pathways in human uveal melanoma cells: interaction with B-Raf/ERK.

Babchia N, Calipel A, Mouriaux F, Faussat AM, Mascarelli F.

Invest Ophthalmol Vis Sci. 2010 Jan;51(1):421-9. doi: 10.1167/iovs.09-3974. Epub 2009 Aug 6.

PMID:
19661225
17.

Basal and treatment-induced activation of AKT mediates resistance to cell death by AZD6244 (ARRY-142886) in Braf-mutant human cutaneous melanoma cells.

Gopal YN, Deng W, Woodman SE, Komurov K, Ram P, Smith PD, Davies MA.

Cancer Res. 2010 Nov 1;70(21):8736-47. doi: 10.1158/0008-5472.CAN-10-0902. Epub 2010 Oct 19.

18.

PI3K pathway is involved in ERK signaling cascade activation by histamine H2R agonist in HEK293T cells.

Alonso N, Diaz Nebreda A, Monczor F, Gutkind JS, Davio C, Fernandez N, Shayo C.

Biochim Biophys Acta. 2016 Sep;1860(9):1998-2007. doi: 10.1016/j.bbagen.2016.06.016. Epub 2016 Jun 15.

PMID:
27316323
19.

PI3K/Akt/mTOR and Ras/Raf/MEK/ERK signaling pathways inhibitors as anticancer agents: Structural and pharmacological perspectives.

Asati V, Mahapatra DK, Bharti SK.

Eur J Med Chem. 2016 Feb 15;109:314-41. doi: 10.1016/j.ejmech.2016.01.012. Epub 2016 Jan 12. Review.

PMID:
26807863
20.

Signal transduction of MEK/ERK and PI3K/Akt activation by hypoxia/reoxygenation in renal epithelial cells.

Kwon DS, Kwon CH, Kim JH, Woo JS, Jung JS, Kim YK.

Eur J Cell Biol. 2006 Nov;85(11):1189-99. Epub 2006 Jul 24.

PMID:
16860436

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