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29117276,32785614,28304224,29530884,31196453,28768335,36031810,31116355,24825642,29133605,25440796,27846344,28927706,30540337,28291870,27039291,28859947,36779348,28122070,32432684,29626068,33980763,28291866,26946077,34620406,29472008,32312223,33078867,32234462,29677301,36877807,29685591,30877491,29716940,31754844,29898218,29792380,30586750,28971955,30025648,20031900,25773378,27322095,26408274,24161333,25881936,31479722,34298555,23128163,27559556,35209731,28877913,29618599,25773607,26920601,29069377,31707849,30073585,31714986,22447012,26074319,23932550,30073316,32381158,31349086,31707832,28374849,30736965,23886915,35831153,28081940,28242176,28215937,27673306,35188949,35581018,35695614,29735587,22463922,27347563,9613910,16503317,28304242,28925859,28555526,30948001,20655105,18772061,28740397,28840737,28097904,30376751,22516441,27618825,30371242,21982310,19329177,25842792,30336824,22085316,15639694,28832867,24678979,26547291,22089718,27264224,24694531,26551986,33941192,30646277,32347885,34375677,29049467,17996658,32609313,32347887,25691546,36602868,24603217,27941065,16533939,32865373,23129602,28623954,31898964,23884353,27533159,27320173,28430910,35368058,30421481,29748356,17719314,28738813,24662398,30586775,31677592,28532771,26968977,15325833,27567901,30422172,33197560,30755061,12479764,35595929,29895529,31759938,31790905,28454801,30983166,30561610,36620965,34796465,31461121,29705799,33034639,33438437,33431716,32543364,32223429,36100012,33755145,30293769,31250329,31434809,32428019,27777279,18997196,33712271,23965489,31841795,29095667,32187462,27092712,36210619,30953107,35287972,35770629,36280861,31726422,31738483,24002795,33904340,33454339,30702994,27829091,30941517,31495548,30270068,36127165,35431172,30986750,30895178,28972004,24481874,33119602,33951415,30280628,23973693,31893957,31411090,31948641,35863366,33998284,20206456,36123891,36154103,22461416,29569492,31166576,29768954,33051646,29980053,33624058,31663632,24877185,31520897,28813214,35642121,31787586,30898607,33185670,25392071,34176598,22453571,28847206,34076665,31006730,31117810,36469793,29116337,33190147,30352291,11434828,29353350,32317124,31301293,30225881,28973087,31405751,36371480,29263150,31707829,35285850,26868195,30847681,36853604,30597485,28768310,21487089,34325831,30685675,29243274,30579806,30046837,32820320,33638801,31718234,35025817,29962050,21392600,32362513,28207168,33998287,17192128,33980690,30821053,34622354,29574925,30851062,31740018,27641514,31208705,31006138,33820931,31707826,35175350,33760276,31706904,30840024,31272931,35381063,32072178,33758291,33063111,34511134,36372869,36876740,29803357,31092149,31861037,31076261,34605920,30125052,31344341,36000434,12809965,10412782,33216139,31862150,25160776,32335402,11352694,24141324,26922537,25082583,33367526,34092409,35604523,21277016,36529993,34622663,15249516,31350672,36252093,34533691,29476887,31927694,28367845,26589368,31987664,31278046,31721979,33813856,33470195,30483816,33096103,37019580,31748467,32605806,34887772,10612322,11779513,27616593,31813618,31202098,28768306,33270123,34751121,23140546,29146277,12727581,30864086,32078484,21989464,21887688,35963739,30273874,32720602,30084224,29103916,30057224,32583886,32480059,34861203,36331326,31412729,31386936,35147685,29992480,30992244,32204951,29754125,21570685,33541430,32892993,30685099,31292087,32680814,30686529,29853312,31440976,30996151,33186535,29491327,35331984,22607822,27838722,28294373,34098569,23532240,35837711,30209099,30393955,29271267,30738610,36104250,30524137,37090440,29898219,32789593,35760720,32720384,34657313,34238445,34749751,30365601,24936119,31648705,24944383,14624134,30404046,27487366,31390907,35841944,34586366,24002278,28423147,22115874,30928825,34481756,12069671,21109302,32770357,24736236,28379800,30873910,30485622,36585131,31519405,30716508,36371856,30994869,36331315,9841599,30746585,31339519,18358084,26864092,35320320,31014162,31707788,35193571,31526399,31048275,34908162,19932775,30843929,35613766,29703626,30091061,33186534,34963300,33283767,12103255,17184550,32470532,31718297,30122341,35916348,30005743,36676782,31371644,30758506,28768753,12867223,20816010,31984235,32650921,32639518,32564340,19452483,30739730,36464556,32336695,36940892,34537830,36538393,36602752,36134834,33355940,30371214,33463677,31501043,22102488,31650209,33903685,33768516,31039062,31041621,31500460,31414562,14693317,27050566,31140709,36696747,32468428,34922872,33289308,34174217,35467312,25579834,32633800,35404972,24225306,24743066,30988003,20941469,36048442,32068819,36172933,31434507,30509144,36351465,28529918,34763772,30704247,17015870,16946569,32821708,29544724,30318492,32202204,29071331,37066797,36877177,33318590,21418030,25824512,34011825,29976096,32179516,18299547,28669994,34042174,33180353,32147651,30485535,12529091,21872439,17398372,34921900,35862449,32452885,12615296,36082945,34872149,23225175,35483753,33394716,30055758,33481866,29512093,31927126,31679643,32227172,35294778,32453609,35598204,35191328,31142078,30782687,36847307,33065780,1459940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Results by year

Year	Number of Results
1988	1
1989	1
1995	2
1997	2
1998	4
1999	6
2000	5
2001	11
2002	12
2003	16
2004	10
2005	10
2006	18
2007	15
2008	14
2009	21
2010	26
2011	27
2012	28
2013	41
2014	39
2015	29
2016	64
2017	94
2018	160
2019	236
2020	218
2021	189
2022	242
2023	110
2024	3

1,458 results

Page of 146

Results by year

Page 1

Clinical Efficacy and Safety of Evolocumab in High-Risk Patients Receiving a Statin: Secondary Analysis of Patients With Low LDL Cholesterol Levels and in Those Already Receiving a Maximal-Potency Statin in a Randomized Clinical Trial.

Giugliano RP, Keech A, Murphy SA, Huber K, Tokgozoglu SL, Lewis BS, Ferreira J, Pineda AL, Somaratne R, Sever PS, Pedersen TR, Sabatine MS. Giugliano RP, et al. JAMA Cardiol. 2017 Dec 1;2(12):1385-1391. doi: 10.1001/jamacardio.2017.3944. JAMA Cardiol. 2017. PMID: 29117276 Free PMC article. Clinical Trial.

Efficacy and Safety of PCSK9 Inhibition With Evolocumab in Reducing Cardiovascular Events in Patients With Metabolic Syndrome Receiving Statin Therapy: Secondary Analysis From the FOURIER Randomized Clinical Trial.

Deedwania P, Murphy SA, Scheen A, Badariene J, Pineda AL, Honarpour N, Keech AC, Sever PS, Pedersen TR, Sabatine MS, Giugliano RP. Deedwania P, et al. JAMA Cardiol. 2021 Feb 1;6(2):139-147. doi: 10.1001/jamacardio.2020.3151. JAMA Cardiol. 2021. PMID: 32785614 Free PMC article. Clinical Trial.

Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease.

Sabatine MS, Giugliano RP, Keech AC, Honarpour N, Wiviott SD, Murphy SA, Kuder JF, Wang H, Liu T, Wasserman SM, Sever PS, Pedersen TR; FOURIER Steering Committee and Investigators. Sabatine MS, et al. N Engl J Med. 2017 May 4;376(18):1713-1722. doi: 10.1056/NEJMoa1615664. Epub 2017 Mar 17. N Engl J Med. 2017. PMID: 28304224 Free article. Clinical Trial.

Inflammatory and Cholesterol Risk in the FOURIER Trial.

Bohula EA, Giugliano RP, Leiter LA, Verma S, Park JG, Sever PS, Lira Pineda A, Honarpour N, Wang H, Murphy SA, Keech A, Pedersen TR, Sabatine MS. Bohula EA, et al. Circulation. 2018 Jul 10;138(2):131-140. doi: 10.1161/CIRCULATIONAHA.118.034032. Epub 2018 Mar 12. Circulation. 2018. PMID: 29530884 Free article. Clinical Trial.

Efficacy and Safety of Evolocumab in Chronic Kidney Disease in the FOURIER Trial.

Charytan DM, Sabatine MS, Pedersen TR, Im K, Park JG, Pineda AL, Wasserman SM, Deedwania P, Olsson AG, Sever PS, Keech AC, Giugliano RP; FOURIER Steering Committee and Investigators. Charytan DM, et al. J Am Coll Cardiol. 2019 Jun 18;73(23):2961-2970. doi: 10.1016/j.jacc.2019.03.513. J Am Coll Cardiol. 2019. PMID: 31196453 Free article. Clinical Trial.

Simulation of Lipid-Lowering Therapy Intensification in a Population With Atherosclerotic Cardiovascular Disease.

Cannon CP, Khan I, Klimchak AC, Reynolds MR, Sanchez RJ, Sasiela WJ. Cannon CP, et al. JAMA Cardiol. 2017 Sep 1;2(9):959-966. doi: 10.1001/jamacardio.2017.2289. JAMA Cardiol. 2017. PMID: 28768335 Free PMC article.

Long-Term Evolocumab in Patients With Established Atherosclerotic Cardiovascular Disease.

O'Donoghue ML, Giugliano RP, Wiviott SD, Atar D, Keech A, Kuder JF, Im K, Murphy SA, Flores-Arredondo JH, López JAG, Elliott-Davey M, Wang B, Monsalvo ML, Abbasi S, Sabatine MS. O'Donoghue ML, et al. Circulation. 2022 Oct 11;146(15):1109-1119. doi: 10.1161/CIRCULATIONAHA.122.061620. Epub 2022 Aug 29. Circulation. 2022. PMID: 36031810 Clinical Trial.

Effect of the PCSK9 Inhibitor Evolocumab on Total Cardiovascular Events in Patients With Cardiovascular Disease: A Prespecified Analysis From the FOURIER Trial.

Murphy SA, Pedersen TR, Gaciong ZA, Ceska R, Ezhov MV, Connolly DL, Jukema JW, Toth K, Tikkanen MJ, Im K, Wiviott SD, Kurtz CE, Honarpour N, Giugliano RP, Keech AC, Sever PS, Sabatine MS. Murphy SA, et al. JAMA Cardiol. 2019 Jul 1;4(7):613-619. doi: 10.1001/jamacardio.2019.0886. JAMA Cardiol. 2019. PMID: 31116355 Free PMC article. Clinical Trial.

Effect of evolocumab or ezetimibe added to moderate- or high-intensity statin therapy on LDL-C lowering in patients with hypercholesterolemia: the LAPLACE-2 randomized clinical trial.

Robinson JG, Nedergaard BS, Rogers WJ, Fialkow J, Neutel JM, Ramstad D, Somaratne R, Legg JC, Nelson P, Scott R, Wasserman SM, Weiss R; LAPLACE-2 Investigators. Robinson JG, et al. JAMA. 2014 May 14;311(18):1870-82. doi: 10.1001/jama.2014.4030. JAMA. 2014. PMID: 24825642 Clinical Trial.

Low-Density Lipoprotein Cholesterol Lowering With Evolocumab and Outcomes in Patients With Peripheral Artery Disease: Insights From the FOURIER Trial (Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk).

Bonaca MP, Nault P, Giugliano RP, Keech AC, Pineda AL, Kanevsky E, Kuder J, Murphy SA, Jukema JW, Lewis BS, Tokgozoglu L, Somaratne R, Sever PS, Pedersen TR, Sabatine MS. Bonaca MP, et al. Circulation. 2018 Jan 23;137(4):338-350. doi: 10.1161/CIRCULATIONAHA.117.032235. Epub 2017 Nov 13. Circulation. 2018. PMID: 29133605 Free article. Clinical Trial.

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