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Items: 1 to 20 of 128

1.

Humanized mouse model supports development, function, and tissue residency of human natural killer cells.

Herndler-Brandstetter D, Shan L, Yao Y, Stecher C, Plajer V, Lietzenmayer M, Strowig T, de Zoete MR, Palm NW, Chen J, Blish CA, Frleta D, Gurer C, Macdonald LE, Murphy AJ, Yancopoulos GD, Montgomery RR, Flavell RA.

Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):E9626-E9634. doi: 10.1073/pnas.1705301114. Epub 2017 Oct 25.

2.

Long-term human CD34+ stem cell-engrafted nonobese diabetic/SCID/IL-2R gamma(null) mice show impaired CD8+ T cell maintenance and a functional arrest of immature NK cells.

André MC, Erbacher A, Gille C, Schmauke V, Goecke B, Hohberger A, Mang P, Wilhelm A, Mueller I, Herr W, Lang P, Handgretinger R, Hartwig UF.

J Immunol. 2010 Sep 1;185(5):2710-20. doi: 10.4049/jimmunol.1000583. Epub 2010 Jul 28.

3.

Natural killer cells generated from cord blood hematopoietic progenitor cells efficiently target bone marrow-residing human leukemia cells in NOD/SCID/IL2Rg(null) mice.

Cany J, van der Waart AB, Tordoir M, Franssen GM, Hangalapura BN, de Vries J, Boerman O, Schaap N, van der Voort R, Spanholtz J, Dolstra H.

PLoS One. 2013 Jun 5;8(6):e64384. doi: 10.1371/journal.pone.0064384. Print 2013.

4.

Human NK cells of mice with reconstituted human immune system components require preactivation to acquire functional competence.

Strowig T, Chijioke O, Carrega P, Arrey F, Meixlsperger S, Rämer PC, Ferlazzo G, Münz C.

Blood. 2010 Nov 18;116(20):4158-67. doi: 10.1182/blood-2010-02-270678. Epub 2010 Jul 29.

5.

Targeted genome editing restores T cell differentiation in a humanized X-SCID pluripotent stem cell disease model.

Alzubi J, Pallant C, Mussolino C, Howe SJ, Thrasher AJ, Cathomen T.

Sci Rep. 2017 Sep 29;7(1):12475. doi: 10.1038/s41598-017-12750-4.

6.

hIL-15-gene modified human natural killer cells (NKL-IL15) exhibit anti-human leukemia functions.

Jiang W, Zhang C, Tian Z, Zhang J.

J Cancer Res Clin Oncol. 2018 Jul;144(7):1279-1288. doi: 10.1007/s00432-018-2654-0. Epub 2018 May 8.

PMID:
29737430
7.

Autonomous growth and increased cytotoxicity of natural killer cells expressing membrane-bound interleukin-15.

Imamura M, Shook D, Kamiya T, Shimasaki N, Chai SM, Coustan-Smith E, Imai C, Campana D.

Blood. 2014 Aug 14;124(7):1081-8. doi: 10.1182/blood-2014-02-556837. Epub 2014 Jul 8.

8.

Utilization of mouse models to decipher natural killer cell biology and potential clinical applications.

Sungur CM, Murphy WJ.

Hematology Am Soc Hematol Educ Program. 2013;2013:227-33. doi: 10.1182/asheducation-2013.1.227. Review.

PMID:
24319185
9.

Preactivation with IL-12, IL-15, and IL-18 induces CD25 and a functional high-affinity IL-2 receptor on human cytokine-induced memory-like natural killer cells.

Leong JW, Chase JM, Romee R, Schneider SE, Sullivan RP, Cooper MA, Fehniger TA.

Biol Blood Marrow Transplant. 2014 Apr;20(4):463-73. doi: 10.1016/j.bbmt.2014.01.006. Epub 2014 Jan 13.

10.

In Vivo Activation of Human NK Cells by Treatment with an Interleukin-15 Superagonist Potently Inhibits Acute In Vivo HIV-1 Infection in Humanized Mice.

Seay K, Church C, Zheng JH, Deneroff K, Ochsenbauer C, Kappes JC, Liu B, Jeng EK, Wong HC, Goldstein H.

J Virol. 2015 Jun;89(12):6264-74. doi: 10.1128/JVI.00563-15. Epub 2015 Apr 1.

11.

Functional CD47/signal regulatory protein alpha (SIRP(alpha)) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivo.

Legrand N, Huntington ND, Nagasawa M, Bakker AQ, Schotte R, Strick-Marchand H, de Geus SJ, Pouw SM, Böhne M, Voordouw A, Weijer K, Di Santo JP, Spits H.

Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13224-9. doi: 10.1073/pnas.1101398108. Epub 2011 Jul 25.

12.

hIL-15 gene-modified human natural killer cells (NKL-IL15) augments the anti-human hepatocellular carcinoma effect in vivo.

Jiang W, Zhang C, Tian Z, Zhang J.

Immunobiology. 2014 Jul;219(7):547-53. doi: 10.1016/j.imbio.2014.03.007. Epub 2014 Mar 20.

PMID:
24721706
13.

A functional DC cross talk promotes human ILC homeostasis in humanized mice.

Lopez-Lastra S, Masse-Ranson G, Fiquet O, Darche S, Serafini N, Li Y, Dusséaux M, Strick-Marchand H, Di Santo JP.

Blood Adv. 2017 Apr 6;1(10):601-614. doi: 10.1182/bloodadvances.2017004358. eCollection 2017 Apr 11.

14.

Generation of functional human T-cell subsets with HLA-restricted immune responses in HLA class I expressing NOD/SCID/IL2r gamma(null) humanized mice.

Shultz LD, Saito Y, Najima Y, Tanaka S, Ochi T, Tomizawa M, Doi T, Sone A, Suzuki N, Fujiwara H, Yasukawa M, Ishikawa F.

Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13022-7. doi: 10.1073/pnas.1000475107. Epub 2010 Jul 6.

15.

The combination of NK and CD8+T cells with CCL20/IL15-armed oncolytic adenoviruses enhances the growth suppression of TERT-positive tumor cells.

Ye JF, Qi WX, Liu MY, Li Y.

Cell Immunol. 2017 Aug;318:35-41. doi: 10.1016/j.cellimm.2017.06.002. Epub 2017 Jun 7.

PMID:
28651743
16.

IL-15 trans-presentation promotes human NK cell development and differentiation in vivo.

Huntington ND, Legrand N, Alves NL, Jaron B, Weijer K, Plet A, Corcuff E, Mortier E, Jacques Y, Spits H, Di Santo JP.

J Exp Med. 2009 Jan 16;206(1):25-34. doi: 10.1084/jem.20082013. Epub 2008 Dec 22.

17.

Genetically re-engineered K562 cells significantly expand and functionally activate cord blood natural killer cells: Potential for adoptive cellular immunotherapy.

Ayello J, Hochberg J, Flower A, Chu Y, Baxi LV, Quish W, van de Ven C, Cairo MS.

Exp Hematol. 2017 Feb;46:38-47. doi: 10.1016/j.exphem.2016.10.003. Epub 2016 Oct 17.

PMID:
27765614
18.

Immunodeficient mouse strains display marked variability in growth of human melanoma lung metastases.

Carreno BM, Garbow JR, Kolar GR, Jackson EN, Engelbach JA, Becker-Hapak M, Carayannopoulos LN, Piwnica-Worms D, Linette GP.

Clin Cancer Res. 2009 May 15;15(10):3277-86. doi: 10.1158/1078-0432.CCR-08-2502. Epub 2009 May 15.

19.

IL-15 has innate anti-tumor activity independent of NK and CD8 T cells.

Davies E, Reid S, Medina MF, Lichty B, Ashkar AA.

J Leukoc Biol. 2010 Sep;88(3):529-36. doi: 10.1189/jlb.0909648. Epub 2010 Jun 10.

PMID:
20538758
20.

Adoptive transfer of osteoclast-expanded natural killer cells for immunotherapy targeting cancer stem-like cells in humanized mice.

Kozlowska AK, Kaur K, Topchyan P, Jewett A.

Cancer Immunol Immunother. 2016 Jul;65(7):835-45. doi: 10.1007/s00262-016-1822-9. Epub 2016 Mar 31. Review.

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