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Multidrug-resistant Neisseria gonorrhoeae infection with ceftriaxone resistance and intermediate resistance to azithromycin, Denmark, 2017.

Terkelsen D, Tolstrup J, Johnsen CH, Lund O, Larsen HK, Worning P, Unemo M, Westh H.

Euro Surveill. 2017 Oct;22(42). doi: 10.2807/1560-7917.ES.2017.22.42.17-00659.


Multidrug-resistant Neisseria gonorrhoeae isolate, belonging to the internationally spreading Japanese FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, Ireland, August 2018.

Golparian D, Rose L, Lynam A, Mohamed A, Bercot B, Ohnishi M, Crowley B, Unemo M.

Euro Surveill. 2018 Nov;23(47). doi: 10.2807/1560-7917.ES.2018.23.47.1800617.


Multidrug-resistant Neisseria gonorrhoeae failing treatment with ceftriaxone and doxycycline in France, November 2017.

Poncin T, Fouere S, Braille A, Camelena F, Agsous M, Bebear C, Kumanski S, Lot F, Mercier-Delarue S, Ngangro NN, Salmona M, Schnepf N, Timsit J, Unemo M, Bercot B.

Euro Surveill. 2018 May;23(21). doi: 10.2807/1560-7917.ES.2018.23.21.1800264.


Correlation between In vitro susceptibility and treatment outcome with azithromycin in gonorrhoea: a prospective study.

Khaki P, Bhalla P, Sharma A, Kumar V.

Indian J Med Microbiol. 2007 Oct;25(4):354-7.


Treatment failure with 2 g of azithromycin (extended-release formulation) in gonorrhoea in Japan caused by the international multidrug-resistant ST1407 strain of Neisseria gonorrhoeae.

Morita-Ishihara T, Unemo M, Furubayashi K, Kawahata T, Shimuta K, Nakayama S, Ohnishi M.

J Antimicrob Chemother. 2014 Aug;69(8):2086-90. doi: 10.1093/jac/dku118. Epub 2014 Apr 28.


Remarkable increase of Neisseria gonorrhoeae with decreased susceptibility of azithromycin and increase in the failure of azithromycin therapy in male gonococcal urethritis in Sendai in 2015.

Yasuda M, Ito S, Hatazaki K, Deguchi T.

J Infect Chemother. 2016 Dec;22(12):841-843. doi: 10.1016/j.jiac.2016.07.012. Epub 2016 Aug 28.


Treatment of gonococcal infection: when one drug is not enough.

Kransdorf LN, Kling JM, Mayer AP.

J Womens Health (Larchmt). 2014 Jul;23(7):627-8. doi: 10.1089/jwh.2014.4820. Epub 2014 Jun 11. No abstract available.


High-level cefixime- and ceftriaxone-resistant Neisseria gonorrhoeae in France: novel penA mosaic allele in a successful international clone causes treatment failure.

Unemo M, Golparian D, Nicholas R, Ohnishi M, Gallay A, Sednaoui P.

Antimicrob Agents Chemother. 2012 Mar;56(3):1273-80. doi: 10.1128/AAC.05760-11. Epub 2011 Dec 12.


Failure of azithromycin 2.0 g in the treatment of gonococcal urethritis caused by high-level resistance in California.

Gose SO, Soge OO, Beebe JL, Nguyen D, Stoltey JE, Bauer HM.

Sex Transm Dis. 2015 May;42(5):279-80. doi: 10.1097/OLQ.0000000000000265.


A Case of Persistent and Possibly Treatment Resistant Pharyngeal Gonorrhea.

Levy V, Pandori M, Berrada ZL, Relucio KI, Lopez TP, Samuel MC, Park IU.

Sex Transm Dis. 2016 Apr;43(4):258-9. doi: 10.1097/OLQ.0000000000000430.


Genetic characterisation of Neisseria gonorrhoeae resistant to both ceftriaxone and azithromycin.

Whiley DM, Jennison A, Pearson J, Lahra MM.

Lancet Infect Dis. 2018 Jul;18(7):717-718. doi: 10.1016/S1473-3099(18)30340-2. No abstract available.


Cluster of Neisseria gonorrhoeae Isolates With High-level Azithromycin Resistance and Decreased Ceftriaxone Susceptibility, Hawaii, 2016.

Katz AR, Komeya AY, Kirkcaldy RD, Whelen AC, Soge OO, Papp JR, Kersh EN, Wasserman GM, O'Connor NP, O'Brien PS, Sato DT, Maningas EV, Kunimoto GY, Tomas JE.

Clin Infect Dis. 2017 Sep 15;65(6):918-923. doi: 10.1093/cid/cix485.


High-level azithromycin-resistant Neisseria gonorrhoeae clinical isolate in France, March 2014.

Bercot B, Belkacem A, Goubard A, Mougari F, Sednaoui P, La Ruche G, Cambau E.

Euro Surveill. 2014 Nov 6;19(44). pii: 20951.


Trends in antimicrobial susceptibility for azithromycin and ceftriaxone in Neisseria gonorrhoeae isolates in Amsterdam, the Netherlands, between 2012 and 2015.

Wind CM, Schim van der Loeff MF, van Dam AP, de Vries HJ, van der Helm JJ.

Euro Surveill. 2017 Jan 5;22(1). pii: 30431. doi: 10.2807/1560-7917.ES.2017.22.1.30431.


Neisseria gonorrhoeae Antimicrobial Susceptibility Surveillance - The Gonococcal Isolate Surveillance Project, 27 Sites, United States, 2014.

Kirkcaldy RD, Harvey A, Papp JR, Del Rio C, Soge OO, Holmes KK, Hook EW 3rd, Kubin G, Riedel S, Zenilman J, Pettus K, Sanders T, Sharpe S, Torrone E.

MMWR Surveill Summ. 2016 Jul 15;65(7):1-19. doi: 10.15585/mmwr.ss6507a1.


Phenotypic and genetic characterization of the first two cases of extended-spectrum-cephalosporin-resistant Neisseria gonorrhoeae infection in South Africa and association with cefixime treatment failure.

Lewis DA, Sriruttan C, Müller EE, Golparian D, Gumede L, Fick D, de Wet J, Maseko V, Coetzee J, Unemo M.

J Antimicrob Chemother. 2013 Jun;68(6):1267-70. doi: 10.1093/jac/dkt034. Epub 2013 Feb 14.


Susceptibility of Neisseria gonorrhoeae to azithromycin and ceftriaxone in China: A retrospective study of national surveillance data from 2013 to 2016.

Yin YP, Han Y, Dai XQ, Zheng HP, Chen SC, Zhu BY, Yong G, Zhong N, Hu LH, Cao WL, Zheng ZJ, Wang F, Zhi Q, Zhu XY, Chen XS.

PLoS Med. 2018 Feb 6;15(2):e1002499. doi: 10.1371/journal.pmed.1002499. eCollection 2018 Feb.


Single-dose cefixime versus single-dose ceftriaxone in the treatment of antimicrobial-resistant Neisseria gonorrhoeae infection.

Plourde PJ, Tyndall M, Agoki E, Ombette J, Slaney LA, D'Costa LJ, Ndinya-Achola JO, Plummer FA.

J Infect Dis. 1992 Oct;166(4):919-22.


Russian gonococcal antimicrobial susceptibility programme (RU-GASP)--resistance in Neisseria gonorrhoeae during 2009-2012 and NG-MAST genotypes in 2011 and 2012.

Kubanova A, Kubanov A, Frigo N, Solomka V, Semina V, Vorobyev D, Khairullin R, Unemo M.

BMC Infect Dis. 2014 Jun 19;14:342. doi: 10.1186/1471-2334-14-342.


An outbreak of high-level azithromycin resistant Neisseria gonorrhoeae in England.

Chisholm SA, Wilson J, Alexander S, Tripodo F, Al-Shahib A, Schaefer U, Lythgow K, Fifer H.

Sex Transm Infect. 2016 Aug;92(5):365-7. doi: 10.1136/sextrans-2015-052312. Epub 2015 Nov 24.


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