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Items: 1 to 20 of 93

1.

Overexpression of Chromosome 21 miRNAs May Affect Mitochondrial Function in the Hearts of Down Syndrome Fetuses.

Izzo A, Manco R, de Cristofaro T, Bonfiglio F, Cicatiello R, Mollo N, De Martino M, Genesio R, Zannini M, Conti A, Nitsch L.

Int J Genomics. 2017;2017:8737649. doi: 10.1155/2017/8737649. Epub 2017 Sep 5.

2.

Human chromosome 21-derived miRNAs are overexpressed in down syndrome brains and hearts.

Kuhn DE, Nuovo GJ, Martin MM, Malana GE, Pleister AP, Jiang J, Schmittgen TD, Terry AV Jr, Gardiner K, Head E, Feldman DS, Elton TS.

Biochem Biophys Res Commun. 2008 Jun 6;370(3):473-7. doi: 10.1016/j.bbrc.2008.03.120. Epub 2008 Apr 1. Retraction in: Biochem Biophys Res Commun. 2013 Jul 5;436(3):564.

3.

Chromosome 21-derived microRNAs provide an etiological basis for aberrant protein expression in human Down syndrome brains.

Kuhn DE, Nuovo GJ, Terry AV Jr, Martin MM, Malana GE, Sansom SE, Pleister AP, Beck WD, Head E, Feldman DS, Elton TS.

J Biol Chem. 2010 Jan 8;285(2):1529-43. doi: 10.1074/jbc.M109.033407. Epub 2009 Nov 6. Retraction in: J Biol Chem. 2013 Feb 8;288(6):4228.

4.

MTUS1 and its targeting miRNAs in colorectal carcinoma: significant associations.

Ozcan O, Kara M, Yumrutas O, Bozgeyik E, Bozgeyik I, Celik OI.

Tumour Biol. 2016 May;37(5):6637-45. doi: 10.1007/s13277-015-4550-4. Epub 2015 Dec 7.

PMID:
26643896
5.

Differentially expressed miRNAs in trisomy 21 placentas.

Svobodová I, Korabečná M, Calda P, Břešťák M, Pazourková E, Pospíšilová Š, Krkavcová M, Novotná M, Hořínek A.

Prenat Diagn. 2016 Aug;36(8):775-84. doi: 10.1002/pd.4861. Epub 2016 Jul 18.

PMID:
27323694
6.

Expression patterns of the chromosome 21 MicroRNA cluster (miR-99a, miR-125b and let-7c) in chorioamniotic membranes.

Modi BP, Washington S, Walsh SW, Jackson-Cook C, Archer KJ, Strauss JF 3rd.

Placenta. 2017 Jan;49:1-9. doi: 10.1016/j.placenta.2016.11.002. Epub 2016 Nov 9.

7.

Analysis of microRNA expression profile by small RNA sequencing in Down syndrome fetuses.

Xu Y, Li W, Liu X, Ma H, Tu Z, Dai Y.

Int J Mol Med. 2013 Nov;32(5):1115-25. doi: 10.3892/ijmm.2013.1499. Epub 2013 Sep 18.

PMID:
24071828
8.

Down syndrome and microRNAs.

Brás A, Rodrigues AS, Gomes B, Rueff J.

Biomed Rep. 2018 Jan;8(1):11-16. doi: 10.3892/br.2017.1019. Epub 2017 Nov 17.

9.

Extracellular chromosome 21-derived microRNAs in euploid & aneuploid pregnancies.

Kotlabova K, Doucha J, Chudoba D, Calda P, Dlouha K, Hromadnikova I.

Indian J Med Res. 2013 Dec;138(6):935-43.

10.

MiR-199a-5p and let-7c cooperatively inhibit migration and invasion by targeting MAP4K3 in hepatocellular carcinoma.

Liu L, Lu L, Zheng A, Xie J, Xue Q, Wang F, Wang X, Zhou H, Tong X, Li Y, Zhu X, Wu G.

Oncotarget. 2017 Feb 21;8(8):13666-13677. doi: 10.18632/oncotarget.14623.

11.

Trisomy-21 gene dosage over-expression of miRNAs results in the haploinsufficiency of specific target proteins.

Elton TS, Sansom SE, Martin MM.

RNA Biol. 2010 Sep-Oct;7(5):540-7. Epub 2010 Sep 1.

12.

Chromosome 21-derived hsa-miR-155-5p regulates mitochondrial biogenesis by targeting Mitochondrial Transcription Factor A (TFAM).

Quiñones-Lombraña A, Blanco JG.

Biochim Biophys Acta. 2015 Jul;1852(7):1420-7. doi: 10.1016/j.bbadis.2015.04.004. Epub 2015 Apr 11.

13.

Upregulated microRNAs in membranous glomerulonephropathy are associated with significant downregulation of IL6 and MYC mRNAs.

Barbagallo C, Passanisi R, Mirabella F, Cirnigliaro M, Costanzo A, Lauretta G, Barbagallo D, Bianchi C, Pagni F, Castorina S, Granata A, Di Pietro C, Ragusa M, Malatino LS, Purrello M.

J Cell Physiol. 2019 Aug;234(8):12625-12636. doi: 10.1002/jcp.27851. Epub 2018 Dec 4.

PMID:
30515781
14.

The transcardiac gradient of cardio-microRNAs in the failing heart.

Marques FZ, Vizi D, Khammy O, Mariani JA, Kaye DM.

Eur J Heart Fail. 2016 Aug;18(8):1000-8. doi: 10.1002/ejhf.517. Epub 2016 Apr 12.

15.

Profiles of serum microRNAs; miR-125b-5p and miR223-3p serve as novel biomarkers for HBV-positive hepatocellular carcinoma.

Giray BG, Emekdas G, Tezcan S, Ulger M, Serin MS, Sezgin O, Altintas E, Tiftik EN.

Mol Biol Rep. 2014 Jul;41(7):4513-9. doi: 10.1007/s11033-014-3322-3. Epub 2014 Mar 5.

PMID:
24595450
16.

Altered expression of mitochondrial and extracellular matrix genes in the heart of human fetuses with chromosome 21 trisomy.

Conti A, Fabbrini F, D'Agostino P, Negri R, Greco D, Genesio R, D'Armiento M, Olla C, Paladini D, Zannini M, Nitsch L.

BMC Genomics. 2007 Aug 7;8:268.

17.

The Long Non-coding RNA MEG3/miR-let-7c-5p Axis Regulates Ethanol-Induced Hepatic Steatosis and Apoptosis by Targeting NLRC5.

Wang Q, Li M, Shen Z, Bu F, Yu H, Pan X, Yang Y, Meng X, Huang C, Li J.

Front Pharmacol. 2018 Apr 10;9:302. doi: 10.3389/fphar.2018.00302. eCollection 2018.

18.

miR-125b-5p and miR-99a-5p downregulate human γδ T-cell activation and cytotoxicity.

Zhu Y, Zhang S, Li Z, Wang H, Li Z, Hu Y, Chen H, Zhang X, Cui L, Zhang J, He W.

Cell Mol Immunol. 2019 Feb;16(2):112-125. doi: 10.1038/cmi.2017.164. Epub 2018 Feb 12.

PMID:
29429995
19.

Cardiomyogenesis is controlled by the miR-99a/let-7c cluster and epigenetic modifications.

Coppola A, Romito A, Borel C, Gehrig C, Gagnebin M, Falconnet E, Izzo A, Altucci L, Banfi S, Antonarakis SE, Minchiotti G, Cobellis G.

Stem Cell Res. 2014 Mar;12(2):323-37. doi: 10.1016/j.scr.2013.11.008. Epub 2013 Nov 28.

20.

Investigation of key miRNAs and target genes in bladder cancer using miRNA profiling and bioinformatic tools.

Canturk KM, Ozdemir M, Can C, Öner S, Emre R, Aslan H, Cilingir O, Ciftci E, Celayir FM, Aldemir O, Özen M, Artan S.

Mol Biol Rep. 2014 Dec;41(12):8127-35. doi: 10.1007/s11033-014-3713-5. Epub 2014 Sep 5.

PMID:
25189652

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