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28989052,32617836,28502748,30554299,27114300,28734977,34360577,30657433,27581775,29263059,25351875,28694077,27771622,23964828,36130102,3018212,26933207,28822812,29500853,28668640,29890717,32476087,26536121,26422151,9476355,23928414,32634218,10445042,27031728,17438048,28583351,24270070,28625736,10398344,21653757,28133872,26129850,26768370,24755107,19454031,27856302,26260509,25681323,20835914,14742211,30866442,32734470,33305309,2554844,16954256,21162638,21865116,17634504,21085862,18039919,26591009,10891108,32333272,24743800,25880588,22747936,26995026,28599858,11469860,18047672,16059669,32992009,25222113,21114623,11816955,24466198,22989196,34073951,28984226,27142238,22862919,21461774,33338280,31962184,11714071,27117164,26547105,35258797,17486256,27291783,33799696,24577793,28923662,30549986,27639705,24652238,23324498,30657948,15365033,27932461,31106759,25727965,18833758,25306202,33909253,32821987,32691258,20149798,30453558,27616185,21143936,31589121,24466257,1766461,28578073,31200551,36336556,28473297,16091902,28780179,29394517,30113216,8767006,33052959,10817227,12682123,12368427,28966608,28734978,29899416,32617835,20119849,35016546,30236508,25135886,36523453,32696418,23274672,28870733,15955240,30500920,31858195,24682409,25429674,28595275,36152775,29538731,29924365,9756611,21938516,29700357,32250218,30854893,36043594,22687471,35506857,14712470,29924034,27014234,22958375,11356139,23715619,24241583,23334066,28492800,6325081,21976602,31963856,28980720,30036959,30850694,32814804,12402027,32427094,32152072,32650369,36613600,12058732,28472585,19470512,19231179,18421569,24342650,9498554,34171998,2250689,8399869,31751534,31748544,22244217,31260179,34278493,22621152,14653521,35714107,11328599,12223188,21745372,20088581,30227928,31242573,11189745,31538565,7765092,31820499,11064323,29898987,23604141,29204336,17073780,32646068,32525156,27431996,32951814,30462271,33034552,8264769,28802152,34873847,15769645,22745268,34600893,29859403,33865058,19762444,31214857,28042367,2017630,29522522,8953084,28504057,19409101,10412578,10678174,2561185,33645521,10855798,8396321,9750340,14685302,11204880,17215622,18089574,35630316,10867234,22037849,30335288,26038739,15707270,11179683,10660637,17482138,14765098,3545213,30302500,10052160,32226021,18755027,37123421,32976723,17028183,3264052,33857369,16248435,34793878,14600201,24966179,11470511,8208242,16309350,31613031,32018005,23940321,22615293,23226146,31621419,30858833,36329281,35335621,7743131,35628630,30546976,3173466,32407475,24855299,23285072,9661017,8405421,12530646,8435404,950381,30799196,21842181,28644714,9468662,17768235,22687470,29518888,36835573,24037291,12369887,31089765,9683645,8264771,23575545,19075057,3711621,32445001,30173763,31812752,7246574,14527742,19286665,11766846,31215386,23453938,29738765,31159249,16954191,35628784,2273168,19383676,15353315,14044948,11922954,24036972,21494601,12424893,28129567,25121983,2596849,35628694,27875967,34204747,35831806,35330320,19515774,8264772,15579109,30341489,23632020,27015292,21082256,4790580,12419614,30710673,22587011,26217702,34881573,30543318,9276941,36012809,21103389,16581251,19730708,26696992,34459954,26955523,8749364,31167942,29799450,25732206,30321990,12464240,34358055,37139574,7121558,29204393,29990750,31119558,19605350,24502137,30956809,12054055,25919277,32269678,23297358,32689941,2452150,31506243,3257867,33232569,2770836,12913803,7200490,32123658,18005930,21445994,21502194,10787440,4083829,9206006,3796713,30009064,29946313,32364293,36294569,31974751,22146963,27034494,1306334,34308006,18769951,10668395,33117312,804993,29903814,33205834,29559998,14625342,30788785,21782265,8803797,33604764,16650767,34755864,9501474,9511231,21411308,692628,32472090,1730627,8845856,9630657,13095987,6424020,30826435,32349673,4822869,33879061,29667657,8483057,20736090,30051576,35730528,17786625,1524134,22208528,36270499,10335451,27449014,30759214,28758170,12462523,13975665,27134873,23261061,9753700,3344031,21740382,29961831,23297351,26823625,14503006,8791791,36422041,35215174,18665399,35559141,23297350,11173529,26697244,22203817,19194056,9972448,1517776,30934594,30643435,34046497,28706855,34850870,32581293,20064075,11358715,13960991,32005397,3574432,12888264,23297353,7494862,20950472,12424900,32885385,33712579,29882883,32748592,35464232,12678786,27102675,28702316,19909539,31655790,28919888,35546755,24432225,29170672,11173528,33948469,3808007,3891870,27626635,33373700,12570738,561914,30921881,1877395,9223185,32694511,10707077,15032601,25697821,35859988,33997360,35330202,35563448,22687467,36044428,19078068,4118275,23632021,25411327,8820851,11908754,30533540,8503858,24421084,33829800,45715,36413274,10777822,14412788,36835781,35448554,32808942,36017280,20571118,7130755,23350195,25331835,22102778,34746111,33179528,12424892,30738898,27894019,29629046,33385580,34829247,1287484,36303887,30978816,34367208,19866937,34117311,36290207,4970679,31998435,1117891,33936006,4004330,8641554,3892731,22303202,32637672,12976368,36914277,31771508,22303269,18918926,5403870,498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In silico analysis of cytochrome P450 monooxygenases in chronic granulomatous infectious fungus Sporothrix schenckii: Special focus on CYP51.

Matowane RG, Wieteska L, Bamal HD, Kgosiemang IKR, Van Wyk M, Manume NA, Abdalla SMH, Mashele SS, Gront D, Syed K. Matowane RG, et al. Biochim Biophys Acta Proteins Proteom. 2018 Jan;1866(1):166-177. doi: 10.1016/j.bbapap.2017.10.003. Epub 2017 Oct 5. Biochim Biophys Acta Proteins Proteom. 2018. PMID: 28989052

Canine sporotrichosis: polyphasic taxonomy and antifungal susceptibility profiles of Sporothrix species in an endemic area in Brazil.

Boechat JS, Pereira SA, de Sá Machado AC, Viana PG, Almeida-Paes R, Zancopé-Oliveira RM, Gremião IDF, de Oliveira MME. Boechat JS, et al. Braz J Microbiol. 2021 Mar;52(1):135-143. doi: 10.1007/s42770-020-00328-8. Epub 2020 Jul 2. Braz J Microbiol. 2021. PMID: 32617836 Free PMC article.

Cytochrome P450 diversity in the tree of life.

Nelson DR. Nelson DR. Biochim Biophys Acta Proteins Proteom. 2018 Jan;1866(1):141-154. doi: 10.1016/j.bbapap.2017.05.003. Epub 2017 May 11. Biochim Biophys Acta Proteins Proteom. 2018. PMID: 28502748 Free PMC article.

Molecular Identification and Antifungal Susceptibility of Clinical Isolates of Sporothrix schenckii Complex in Medellin, Colombia.

Flórez-Muñoz SV, Alzate JF, Mesa-Arango AC. Flórez-Muñoz SV, et al. Mycopathologia. 2019 Feb;184(1):53-63. doi: 10.1007/s11046-018-0310-5. Epub 2018 Dec 15. Mycopathologia. 2019. PMID: 30554299

Atypical Clinical Presentation of Sporotrichosis Caused by Sporothrix globosa Resistant to Itraconazole.

Fischman Gompertz O, Rodrigues AM, Fernandes GF, Bentubo HD, de Camargo ZP, Petri V. Fischman Gompertz O, et al. Am J Trop Med Hyg. 2016 Jun 1;94(6):1218-22. doi: 10.4269/ajtmh.15-0267. Epub 2016 Apr 25. Am J Trop Med Hyg. 2016. PMID: 27114300 Free PMC article.

Modulation of the interaction between human P450 3A4 and B. megaterium reductase via engineered loops.

Castrignanò S, D'Avino S, Di Nardo G, Catucci G, Sadeghi SJ, Gilardi G. Castrignanò S, et al. Biochim Biophys Acta Proteins Proteom. 2018 Jan;1866(1):116-125. doi: 10.1016/j.bbapap.2017.07.009. Epub 2017 Jul 19. Biochim Biophys Acta Proteins Proteom. 2018. PMID: 28734977

In Silico Structural Modeling and Analysis of Interactions of Tremellomycetes Cytochrome P450 Monooxygenases CYP51s with Substrates and Azoles.

Akapo OO, Macnar JM, Kryś JD, Syed PR, Syed K, Gront D. Akapo OO, et al. Int J Mol Sci. 2021 Jul 22;22(15):7811. doi: 10.3390/ijms22157811. Int J Mol Sci. 2021. PMID: 34360577 Free PMC article.

Novel Point Mutations in cyp51A and cyp51B Genes Associated with Itraconazole and Posaconazole Resistance in Aspergillus clavatus Isolates.

Abastabar M, Hosseini T, Valadan R, Lagzian M, Haghani I, Aslani N, Badali H, Nouripour-Sisakht S, Nazeri M, Gholami S, Vakili M, Bowyer P, Shokohi T, Hedayati MT. Abastabar M, et al. Microb Drug Resist. 2019 Jun;25(5):652-662. doi: 10.1089/mdr.2018.0300. Epub 2019 Jan 18. Microb Drug Resist. 2019. PMID: 30657433

Studies in Phylogeny, Development of Rapid IdentificationMethods, Antifungal Susceptibility, and Growth Rates of Clinical Strains of Sporothrix schenckii Complex in Japan.

Suzuki R, Yikelamu A, Tanaka R, Igawa K, Yokozeki H, Yaguchi T. Suzuki R, et al. Med Mycol J. 2016;57(3):E47-57. doi: 10.3314/mmj.16-00005. Med Mycol J. 2016. PMID: 27581775 Free article.

Impact of Homologous Resistance Mutations from Pathogenic Yeast on Saccharomyces cerevisiae Lanosterol 14α-Demethylase.

Sagatova AA, Keniya MV, Tyndall JDA, Monk BC. Sagatova AA, et al. Antimicrob Agents Chemother. 2018 Feb 23;62(3):e02242-17. doi: 10.1128/AAC.02242-17. Print 2018 Mar. Antimicrob Agents Chemother. 2018. PMID: 29263059 Free PMC article.

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