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Items: 1 to 20 of 128

1.

Upregulation of Human Endogenous Retrovirus-K Is Linked to Immunity and Inflammation in Pulmonary Arterial Hypertension.

Saito T, Miyagawa K, Chen SY, Tamosiuniene R, Wang L, Sharpe O, Samayoa E, Harada D, Moonen JAJ, Cao A, Chen PI, Hennigs JK, Gu M, Li CG, Leib RD, Li D, Adams CM, Del Rosario PA, Bill M, Haddad F, Montoya JG, Robinson WH, Fantl WJ, Nolan GP, Zamanian RT, Nicolls MR, Chiu CY, Ariza ME, Rabinovitch M.

Circulation. 2017 Nov 14;136(20):1920-1935. doi: 10.1161/CIRCULATIONAHA.117.027589. Epub 2017 Sep 21.

2.

A human endogenous retrovirus K dUTPase triggers a TH1, TH17 cytokine response: does it have a role in psoriasis?

Ariza ME, Williams MV.

J Invest Dermatol. 2011 Dec;131(12):2419-27. doi: 10.1038/jid.2011.217. Epub 2011 Jul 21.

3.

Immune and inflammatory cell involvement in the pathology of idiopathic pulmonary arterial hypertension.

Savai R, Pullamsetti SS, Kolbe J, Bieniek E, Voswinckel R, Fink L, Scheed A, Ritter C, Dahal BK, Vater A, Klussmann S, Ghofrani HA, Weissmann N, Klepetko W, Banat GA, Seeger W, Grimminger F, Schermuly RT.

Am J Respir Crit Care Med. 2012 Nov 1;186(9):897-908. doi: 10.1164/rccm.201202-0335OC. Epub 2012 Sep 6.

PMID:
22955318
4.

In Pulmonary Arterial Hypertension, Reduced BMPR2 Promotes Endothelial-to-Mesenchymal Transition via HMGA1 and Its Target Slug.

Hopper RK, Moonen JR, Diebold I, Cao A, Rhodes CJ, Tojais NF, Hennigs JK, Gu M, Wang L, Rabinovitch M.

Circulation. 2016 May 3;133(18):1783-94. doi: 10.1161/CIRCULATIONAHA.115.020617. Epub 2016 Apr 4.

5.

Krüppel-like factor 5 contributes to pulmonary artery smooth muscle proliferation and resistance to apoptosis in human pulmonary arterial hypertension.

Courboulin A, Tremblay VL, Barrier M, Meloche J, Jacob MH, Chapolard M, Bisserier M, Paulin R, Lambert C, Provencher S, Bonnet S.

Respir Res. 2011 Sep 27;12:128. doi: 10.1186/1465-9921-12-128.

6.

Vascular receptor autoantibodies in pulmonary arterial hypertension associated with systemic sclerosis.

Becker MO, Kill A, Kutsche M, Guenther J, Rose A, Tabeling C, Witzenrath M, Kühl AA, Heidecke H, Ghofrani HA, Tiede H, Schermuly RT, Nickel N, Hoeper MM, Lukitsch I, Gollasch M, Kuebler WM, Bock S, Burmester GR, Dragun D, Riemekasten G.

Am J Respir Crit Care Med. 2014 Oct 1;190(7):808-17. doi: 10.1164/rccm.201403-0442OC.

PMID:
25181620
7.

Iptakalim attenuates hypoxia-induced pulmonary arterial hypertension in rats by endothelial function protection.

Zhu R, Bi LQ, Wu SL, Li L, Kong H, Xie WP, Wang H, Meng ZL.

Mol Med Rep. 2015 Aug;12(2):2945-52. doi: 10.3892/mmr.2015.3695. Epub 2015 Apr 28.

PMID:
25936382
8.

Regulatory T cells limit vascular endothelial injury and prevent pulmonary hypertension.

Tamosiuniene R, Tian W, Dhillon G, Wang L, Sung YK, Gera L, Patterson AJ, Agrawal R, Rabinovitch M, Ambler K, Long CS, Voelkel NF, Nicolls MR.

Circ Res. 2011 Sep 30;109(8):867-79. doi: 10.1161/CIRCRESAHA.110.236927. Epub 2011 Aug 25.

9.

Delayed Microvascular Shear Adaptation in Pulmonary Arterial Hypertension. Role of Platelet Endothelial Cell Adhesion Molecule-1 Cleavage.

Szulcek R, Happé CM, Rol N, Fontijn RD, Dickhoff C, Hartemink KJ, Grünberg K, Tu L, Timens W, Nossent GD, Paul MA, Leyen TA, Horrevoets AJ, de Man FS, Guignabert C, Yu PB, Vonk-Noordegraaf A, van Nieuw Amerongen GP, Bogaard HJ.

Am J Respir Crit Care Med. 2016 Jun 15;193(12):1410-20. doi: 10.1164/rccm.201506-1231OC.

PMID:
26760925
10.

Severe pulmonary arterial hypertension induced by SU5416 and ovalbumin immunization.

Mizuno S, Farkas L, Al Husseini A, Farkas D, Gomez-Arroyo J, Kraskauskas D, Nicolls MR, Cool CD, Bogaard HJ, Voelkel NF.

Am J Respir Cell Mol Biol. 2012 Nov;47(5):679-87. doi: 10.1165/rcmb.2012-0077OC. Epub 2012 Jul 27.

11.

Proteomic analysis implicates translationally controlled tumor protein as a novel mediator of occlusive vascular remodeling in pulmonary arterial hypertension.

Lavoie JR, Ormiston ML, Perez-Iratxeta C, Courtman DW, Jiang B, Ferrer E, Caruso P, Southwood M, Foster WS, Morrell NW, Stewart DJ.

Circulation. 2014 May 27;129(21):2125-35. doi: 10.1161/CIRCULATIONAHA.114.008777. Epub 2014 Mar 21.

PMID:
24657995
12.

Proinflammatory Signature of the Dysfunctional Endothelium in Pulmonary Hypertension. Role of the Macrophage Migration Inhibitory Factor/CD74 Complex.

Le Hiress M, Tu L, Ricard N, Phan C, Thuillet R, Fadel E, Dorfmüller P, Montani D, de Man F, Humbert M, Huertas A, Guignabert C.

Am J Respir Crit Care Med. 2015 Oct 15;192(8):983-97. doi: 10.1164/rccm.201402-0322OC.

PMID:
26203495
13.

Inflammatory mechanisms in the pathogenesis of pulmonary arterial hypertension.

El Chami H, Hassoun PM.

Compr Physiol. 2011 Oct;1(4):1929-41. doi: 10.1002/cphy.c100028. Review.

PMID:
23733693
14.

Pulmonary lymphoid neogenesis in idiopathic pulmonary arterial hypertension.

Perros F, Dorfmüller P, Montani D, Hammad H, Waelput W, Girerd B, Raymond N, Mercier O, Mussot S, Cohen-Kaminsky S, Humbert M, Lambrecht BN.

Am J Respir Crit Care Med. 2012 Feb 1;185(3):311-21. doi: 10.1164/rccm.201105-0927OC. Epub 2011 Nov 22.

PMID:
22108206
15.

Type I immune response cytokine-chemokine cascade is associated with pulmonary arterial hypertension.

Ross DJ, Strieter RM, Fishbein MC, Ardehali A, Belperio JA.

J Heart Lung Transplant. 2012 Aug;31(8):865-73. doi: 10.1016/j.healun.2012.04.008. Epub 2012 May 30.

PMID:
22658713
16.

SAMHD1 suppresses innate immune responses to viral infections and inflammatory stimuli by inhibiting the NF-κB and interferon pathways.

Chen S, Bonifati S, Qin Z, St Gelais C, Kodigepalli KM, Barrett BS, Kim SH, Antonucci JM, Ladner KJ, Buzovetsky O, Knecht KM, Xiong Y, Yount JS, Guttridge DC, Santiago ML, Wu L.

Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):E3798-E3807. doi: 10.1073/pnas.1801213115. Epub 2018 Apr 2.

17.

Nuclear factor κ-B is activated in the pulmonary vessels of patients with end-stage idiopathic pulmonary arterial hypertension.

Price LC, Caramori G, Perros F, Meng C, Gambaryan N, Dorfmuller P, Montani D, Casolari P, Zhu J, Dimopoulos K, Shao D, Girerd B, Mumby S, Proudfoot A, Griffiths M, Papi A, Humbert M, Adcock IM, Wort SJ.

PLoS One. 2013 Oct 4;8(10):e75415. doi: 10.1371/journal.pone.0075415. eCollection 2013.

18.

Baicalein attenuates monocrotaline-induced pulmonary arterial hypertension by inhibiting vascular remodeling in rats.

Shi R, Wei Z, Zhu D, Fu N, Wang C, Yin S, Liang Y, Xing J, Wang X, Wang Y.

Pulm Pharmacol Ther. 2018 Feb;48:124-135. doi: 10.1016/j.pupt.2017.11.003. Epub 2017 Nov 10.

PMID:
29133079
19.

Potassium Channel Subfamily K Member 3 (KCNK3) Contributes to the Development of Pulmonary Arterial Hypertension.

Antigny F, Hautefort A, Meloche J, Belacel-Ouari M, Manoury B, Rucker-Martin C, Péchoux C, Potus F, Nadeau V, Tremblay E, Ruffenach G, Bourgeois A, Dorfmüller P, Breuils-Bonnet S, Fadel E, Ranchoux B, Jourdon P, Girerd B, Montani D, Provencher S, Bonnet S, Simonneau G, Humbert M, Perros F.

Circulation. 2016 Apr 5;133(14):1371-85. doi: 10.1161/CIRCULATIONAHA.115.020951. Epub 2016 Feb 24.

PMID:
26912814
20.

Activated CD47 promotes pulmonary arterial hypertension through targeting caveolin-1.

Bauer PM, Bauer EM, Rogers NM, Yao M, Feijoo-Cuaresma M, Pilewski JM, Champion HC, Zuckerbraun BS, Calzada MJ, Isenberg JS.

Cardiovasc Res. 2012 Mar 15;93(4):682-93. doi: 10.1093/cvr/cvr356. Epub 2012 Jan 2.

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