Similar articles for PMID: 28778924

Year	Number of Results
1995	1
1996	1
1999	2
2000	1
2001	5
2002	3
2004	6
2005	4
2006	2
2007	1
2008	4
2009	2
2010	9
2011	10
2012	13
2013	19
2014	13
2015	13
2016	9
2017	10
2018	9
2019	9
2020	20
2021	18
2022	31
2023	10
2024	0

1

Arginine mutations in antibody complementarity-determining regions display context-dependent affinity/specificity trade-offs.

Tiller KE, Li L, Kumar S, Julian MC, Garde S, Tessier PM. Tiller KE, et al. J Biol Chem. 2017 Oct 6;292(40):16638-16652. doi: 10.1074/jbc.M117.783837. Epub 2017 Aug 4. J Biol Chem. 2017. PMID: 28778924 Free PMC article.

2

Aggregation-resistant domain antibodies engineered with charged mutations near the edges of the complementarity-determining regions.

Perchiacca JM, Ladiwala AR, Bhattacharya M, Tessier PM. Perchiacca JM, et al. Protein Eng Des Sel. 2012 Oct;25(10):591-601. doi: 10.1093/protein/gzs042. Epub 2012 Jul 27. Protein Eng Des Sel. 2012. PMID: 22843678

3

Design and Optimization of Anti-amyloid Domain Antibodies Specific for β-Amyloid and Islet Amyloid Polypeptide.

Lee CC, Julian MC, Tiller KE, Meng F, DuConge SE, Akter R, Raleigh DP, Tessier PM. Lee CC, et al. J Biol Chem. 2016 Feb 5;291(6):2858-73. doi: 10.1074/jbc.M115.682336. Epub 2015 Nov 24. J Biol Chem. 2016. PMID: 26601942 Free PMC article.

4

Optimal charged mutations in the complementarity-determining regions that prevent domain antibody aggregation are dependent on the antibody scaffold.

Perchiacca JM, Lee CC, Tessier PM. Perchiacca JM, et al. Protein Eng Des Sel. 2014 Feb;27(2):29-39. doi: 10.1093/protein/gzt058. Epub 2014 Jan 6. Protein Eng Des Sel. 2014. PMID: 24398633

5

Efficient affinity maturation of antibody variable domains requires co-selection of compensatory mutations to maintain thermodynamic stability.

Julian MC, Li L, Garde S, Wilen R, Tessier PM. Julian MC, et al. Sci Rep. 2017 Mar 28;7:45259. doi: 10.1038/srep45259. Sci Rep. 2017. PMID: 28349921 Free PMC article.

6

Facile Affinity Maturation of Antibody Variable Domains Using Natural Diversity Mutagenesis.

Tiller KE, Chowdhury R, Li T, Ludwig SD, Sen S, Maranas CD, Tessier PM. Tiller KE, et al. Front Immunol. 2017 Sep 4;8:986. doi: 10.3389/fimmu.2017.00986. eCollection 2017. Front Immunol. 2017. PMID: 28928732 Free PMC article.

7

Nature-inspired design and evolution of anti-amyloid antibodies.

Julian MC, Rabia LA, Desai AA, Arsiwala A, Gerson JE, Paulson HL, Kane RS, Tessier PM. Julian MC, et al. J Biol Chem. 2019 May 24;294(21):8438-8451. doi: 10.1074/jbc.RA118.004731. Epub 2019 Mar 27. J Biol Chem. 2019. PMID: 30918024 Free PMC article.

8

Combinatorial mutagenesis with alternative CDR-L1 and -H2 loop lengths contributes to affinity maturation of antibodies.

Brockmann EC, Pyykkö M, Hannula H, Khan K, Lamminmäki U, Huovinen T. Brockmann EC, et al. N Biotechnol. 2021 Jan 25;60:173-182. doi: 10.1016/j.nbt.2020.09.002. Epub 2020 Oct 8. N Biotechnol. 2021. PMID: 33039698

9

Net charge of antibody complementarity-determining regions is a key predictor of specificity.

Rabia LA, Zhang Y, Ludwig SD, Julian MC, Tessier PM. Rabia LA, et al. Protein Eng Des Sel. 2018 Nov 1;31(11):409-418. doi: 10.1093/protein/gzz002. Protein Eng Des Sel. 2018. PMID: 30770934 Free PMC article.

10

A Combination of Structural and Empirical Analyses Delineates the Key Contacts Mediating Stability and Affinity Increases in an Optimized Biotherapeutic Single-chain Fv (scFv).

Tu C, Terraube V, Tam AS, Stochaj W, Fennell BJ, Lin L, Stahl M, LaVallie ER, Somers W, Finlay WJ, Mosyak L, Bard J, Cunningham O. Tu C, et al. J Biol Chem. 2016 Jan 15;291(3):1267-76. doi: 10.1074/jbc.M115.688010. Epub 2015 Oct 29. J Biol Chem. 2016. PMID: 26515064 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Results by year

Text availability

Article attribute

Article type

Publication date

197 results

Results by year