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Items: 1 to 20 of 113

1.

ELABELA Improves Cardio-Renal Outcome in Fatal Experimental Septic Shock.

Coquerel D, Chagnon F, Sainsily X, Dumont L, Murza A, Côté J, Dumaine R, Sarret P, Marsault É, Salvail D, Auger-Messier M, Lesur O.

Crit Care Med. 2017 Nov;45(11):e1139-e1148. doi: 10.1097/CCM.0000000000002639.

PMID:
28777197
2.

Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial Hypertension.

Yang P, Read C, Kuc RE, Buonincontri G, Southwood M, Torella R, Upton PD, Crosby A, Sawiak SJ, Carpenter TA, Glen RC, Morrell NW, Maguire JJ, Davenport AP.

Circulation. 2017 Mar 21;135(12):1160-1173. doi: 10.1161/CIRCULATIONAHA.116.023218. Epub 2017 Jan 30.

3.

Apelin Compared With Dobutamine Exerts Cardioprotection and Extends Survival in a Rat Model of Endotoxin-Induced Myocardial Dysfunction.

Chagnon F, Coquerel D, Salvail D, Marsault E, Dumaine R, Auger-Messier M, Sarret P, Lesur O.

Crit Care Med. 2017 Apr;45(4):e391-e398. doi: 10.1097/CCM.0000000000002097.

PMID:
27571457
4.

ELABELA-APJ axis protects from pressure overload heart failure and angiotensin II-induced cardiac damage.

Sato T, Sato C, Kadowaki A, Watanabe H, Ho L, Ishida J, Yamaguchi T, Kimura A, Fukamizu A, Penninger JM, Reversade B, Ito H, Imai Y, Kuba K.

Cardiovasc Res. 2017 Jun 1;113(7):760-769. doi: 10.1093/cvr/cvx061.

PMID:
28371822
5.

Therapeutic effects of hypertonic saline on peritonitis-induced septic shock with multiple organ dysfunction syndrome in rats.

Shih CC, Chen SJ, Chen A, Wu JY, Liaw WJ, Wu CC.

Crit Care Med. 2008 Jun;36(6):1864-72. doi: 10.1097/CCM.0b013e318173f982.

PMID:
18496380
6.

The apelinergic system as an alternative to catecholamines in low-output septic shock.

Coquerel D, Sainsily X, Dumont L, Sarret P, Marsault É, Auger-Messier M, Lesur O.

Crit Care. 2018 Jan 19;22(1):10. doi: 10.1186/s13054-018-1942-z.

7.

Discovery and Structure-Activity Relationship of a Bioactive Fragment of ELABELA that Modulates Vascular and Cardiac Functions.

Murza A, Sainsily X, Coquerel D, Côté J, Marx P, Besserer-Offroy É, Longpré JM, Lainé J, Reversade B, Salvail D, Leduc R, Dumaine R, Lesur O, Auger-Messier M, Sarret P, Marsault É.

J Med Chem. 2016 Apr 14;59(7):2962-72. doi: 10.1021/acs.jmedchem.5b01549. Epub 2016 Mar 30.

PMID:
26986036
8.

Apelin, Elabela/Toddler, and biased agonists as novel therapeutic agents in the cardiovascular system.

Yang P, Maguire JJ, Davenport AP.

Trends Pharmacol Sci. 2015 Sep;36(9):560-7. doi: 10.1016/j.tips.2015.06.002. Epub 2015 Jul 1. Review.

9.

4-Phenylbutyric Acid Reveals Good Beneficial Effects on Vital Organ Function via Anti-Endoplasmic Reticulum Stress in Septic Rats.

Liu L, Wu H, Zang J, Yang G, Zhu Y, Wu Y, Chen X, Lan D, Li T.

Crit Care Med. 2016 Aug;44(8):e689-701. doi: 10.1097/CCM.0000000000001662.

PMID:
26958745
10.

Administration of human inter-alpha-inhibitors maintains hemodynamic stability and improves survival during sepsis.

Yang S, Lim YP, Zhou M, Salvemini P, Schwinn H, Josic D, Koo DJ, Chaudry IH, Wang P.

Crit Care Med. 2002 Mar;30(3):617-22.

PMID:
11990925
11.

β1-Adrenergic Inhibition Improves Cardiac and Vascular Function in Experimental Septic Shock.

Kimmoun A, Louis H, Al Kattani N, Delemazure J, Dessales N, Wei C, Marie PY, Issa K, Levy B.

Crit Care Med. 2015 Sep;43(9):e332-40. doi: 10.1097/CCM.0000000000001078.

PMID:
25962080
12.

If Channel Inhibition With Ivabradine Does Not Improve Cardiac and Vascular Function in Experimental Septic Shock.

Wei C, Al Kattani N, Louis H, Albuisson E, Levy B, Kimmoun A.

Shock. 2016 Sep;46(3):297-303. doi: 10.1097/SHK.0000000000000593.

PMID:
26909707
13.

Sustained ELABELA Gene Therapy in High-salt Diet-induced Hypertensive Rats.

Schreiber CA, Holditch SJ, Generous A, Ikeda Y.

Curr Gene Ther. 2017;16(5):349-360. doi: 10.2174/1566523217666161121111906.

PMID:
27903222
14.

Anti-Inflammatory Profile of Levosimendan in Cecal Ligation-Induced Septic Mice and in Lipopolysaccharide-Stimulated Macrophages.

Wang Q, Yokoo H, Takashina M, Sakata K, Ohashi W, Abedelzaher LA, Imaizumi T, Sakamoto T, Hattori K, Matsuda N, Hattori Y.

Crit Care Med. 2015 Nov;43(11):e508-20. doi: 10.1097/CCM.0000000000001269.

PMID:
26468714
15.

The endogenous peptide apelin potently improves cardiac contractility and reduces cardiac loading in vivo.

Ashley EA, Powers J, Chen M, Kundu R, Finsterbach T, Caffarelli A, Deng A, Eichhorn J, Mahajan R, Agrawal R, Greve J, Robbins R, Patterson AJ, Bernstein D, Quertermous T.

Cardiovasc Res. 2005 Jan 1;65(1):73-82.

16.

Effect of apelin on the cardiac hemodynamics in hypertensive rats with heart failure.

Pang H, Han B, Yu T, Zong Z.

Int J Mol Med. 2014 Sep;34(3):756-64. doi: 10.3892/ijmm.2014.1829. Epub 2014 Jul 2.

17.

Elabela-apelin receptor signaling pathway is functional in mammalian systems.

Wang Z, Yu D, Wang M, Wang Q, Kouznetsova J, Yang R, Qian K, Wu W, Shuldiner A, Sztalryd C, Zou M, Zheng W, Gong DW.

Sci Rep. 2015 Feb 2;5:8170. doi: 10.1038/srep08170.

18.

[The Action of Apelin-12 and Its Analog on Hemodynamics and Cardiac Contractile Function of Rats With Isoproterenol-Induced Myocardial Lesion].

Lakomkin VL, Abramov AA, Lukoshkova EV, Lakomkin SV, Gramovich VV, Vyborov ON, Undrovinas NA, Ermishkin VV, Tsyplenkova VG, Shirinsky VP, Kapelko VI.

Kardiologiia. 2015;55(6):54-62. Russian.

PMID:
26625520
19.

Post-infarct treatment with [Pyr(1)]apelin-13 improves myocardial function by increasing neovascularization and overexpression of angiogenic growth factors in rats.

Azizi Y, Faghihi M, Imani A, Roghani M, Zekri A, Mobasheri MB, Rastgar T, Moghimian M.

Eur J Pharmacol. 2015 Aug 15;761:101-8. doi: 10.1016/j.ejphar.2015.04.034. Epub 2015 May 1.

PMID:
25936512
20.

Ghrelin inhibits proinflammatory responses and prevents cognitive impairment in septic rats.

Wei H, Cao X, Zeng Q, Zhang F, Xue Q, Luo Y, Lee JW, Yu B, Feng X.

Crit Care Med. 2015 May;43(5):e143-50. doi: 10.1097/CCM.0000000000000930.

PMID:
25756415

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