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Items: 1 to 20 of 222

1.

Ubiquitin Ligase WWP1 Interacts with Ebola Virus VP40 To Regulate Egress.

Han Z, Sagum CA, Takizawa F, Ruthel G, Berry CT, Kong J, Sunyer JO, Freedman BD, Bedford MT, Sidhu SS, Sudol M, Harty RN.

J Virol. 2017 Sep 27;91(20). pii: e00812-17. doi: 10.1128/JVI.00812-17. Print 2017 Oct 15.

2.

ITCH E3 Ubiquitin Ligase Interacts with Ebola Virus VP40 To Regulate Budding.

Han Z, Sagum CA, Bedford MT, Sidhu SS, Sudol M, Harty RN.

J Virol. 2016 Sep 29;90(20):9163-71. doi: 10.1128/JVI.01078-16. Print 2016 Oct 15.

3.

Chaperone-Mediated Autophagy Protein BAG3 Negatively Regulates Ebola and Marburg VP40-Mediated Egress.

Liang J, Sagum CA, Bedford MT, Sidhu SS, Sudol M, Han Z, Harty RN.

PLoS Pathog. 2017 Jan 11;13(1):e1006132. doi: 10.1371/journal.ppat.1006132. eCollection 2017 Jan. Erratum in: PLoS Pathog. 2017 Jul 19;13(7):e1006519.

4.

Suppressor of Cytokine Signaling 3 Is an Inducible Host Factor That Regulates Virus Egress during Ebola Virus Infection.

Okumura A, Rasmussen AL, Halfmann P, Feldmann F, Yoshimura A, Feldmann H, Kawaoka Y, Harty RN, Katze MG.

J Virol. 2015 Oct;89(20):10399-406. doi: 10.1128/JVI.01736-15. Epub 2015 Aug 5.

5.

ALIX Rescues Budding of a Double PTAP/PPEY L-Domain Deletion Mutant of Ebola VP40: A Role for ALIX in Ebola Virus Egress.

Han Z, Madara JJ, Liu Y, Liu W, Ruthel G, Freedman BD, Harty RN.

J Infect Dis. 2015 Oct 1;212 Suppl 2:S138-45. doi: 10.1093/infdis/jiu838. Epub 2015 Mar 18.

6.

Conserved motifs within Ebola and Marburg virus VP40 proteins are important for stability, localization, and subsequent budding of virus-like particles.

Liu Y, Cocka L, Okumura A, Zhang YA, Sunyer JO, Harty RN.

J Virol. 2010 Mar;84(5):2294-303. doi: 10.1128/JVI.02034-09. Epub 2009 Dec 23.

7.

Small-molecule probes targeting the viral PPxY-host Nedd4 interface block egress of a broad range of RNA viruses.

Han Z, Lu J, Liu Y, Davis B, Lee MS, Olson MA, Ruthel G, Freedman BD, Schnell MJ, Wrobel JE, Reitz AB, Harty RN.

J Virol. 2014 Jul;88(13):7294-306. doi: 10.1128/JVI.00591-14. Epub 2014 Apr 16.

8.

ISG15 inhibits Ebola VP40 VLP budding in an L-domain-dependent manner by blocking Nedd4 ligase activity.

Okumura A, Pitha PM, Harty RN.

Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3974-9. doi: 10.1073/pnas.0710629105. Epub 2008 Feb 27.

9.

Nedd4 regulates egress of Ebola virus-like particles from host cells.

Yasuda J, Nakao M, Kawaoka Y, Shida H.

J Virol. 2003 Sep;77(18):9987-92.

10.
11.

Recombinant Modified Vaccinia Virus Ankara Generating Ebola Virus-Like Particles.

Schweneker M, Laimbacher AS, Zimmer G, Wagner S, Schraner EM, Wolferstätter M, Klingenberg M, Dirmeier U, Steigerwald R, Lauterbach H, Hochrein H, Chaplin P, Suter M, Hausmann J.

J Virol. 2017 May 12;91(11). pii: e00343-17. doi: 10.1128/JVI.00343-17. Print 2017 Jun 1.

12.

The Host E3-Ubiquitin Ligase TRIM6 Ubiquitinates the Ebola Virus VP35 Protein and Promotes Virus Replication.

Bharaj P, Atkins C, Luthra P, Giraldo MI, Dawes BE, Miorin L, Johnson JR, Krogan NJ, Basler CF, Freiberg AN, Rajsbaum R.

J Virol. 2017 Aug 24;91(18). pii: e00833-17. doi: 10.1128/JVI.00833-17. Print 2017 Sep 15.

13.
14.

Human transbodies to VP40 inhibit cellular egress of Ebola virus-like particles.

Teimoori S, Seesuay W, Jittavisutthikul S, Chaisri U, Sookrung N, Densumite J, Saelim N, Chulanetra M, Maneewatch S, Chaicumpa W.

Biochem Biophys Res Commun. 2016 Oct 14;479(2):245-252. doi: 10.1016/j.bbrc.2016.09.052. Epub 2016 Sep 13.

PMID:
27638305
15.

A luciferase-based budding assay for Ebola virus.

McCarthy SE, Licata JM, Harty RN.

J Virol Methods. 2006 Oct;137(1):115-9. Epub 2006 Jul 11.

PMID:
16837071
16.

A loop region in the N-terminal domain of Ebola virus VP40 is important in viral assembly, budding, and egress.

Adu-Gyamfi E, Soni SP, Jee CS, Digman MA, Gratton E, Stahelin RV.

Viruses. 2014 Oct 17;6(10):3837-54. doi: 10.3390/v6103837.

17.

Regulation of Ebola virus VP40 matrix protein by SUMO.

Baz-Martínez M, El Motiam A, Ruibal P, Condezo GN, de la Cruz-Herrera CF, Lang V, Collado M, San Martín C, Rodríguez MS, Muñoz-Fontela C, Rivas C.

Sci Rep. 2016 Nov 16;6:37258. doi: 10.1038/srep37258.

18.

Budding of PPxY-containing rhabdoviruses is not dependent on host proteins TGS101 and VPS4A.

Irie T, Licata JM, McGettigan JP, Schnell MJ, Harty RN.

J Virol. 2004 Mar;78(6):2657-65. Erratum in: J Virol. 2004 May;78(10):5532.

19.

Host Protein BAG3 is a Negative Regulator of Lassa VLP Egress.

Han Z, Schwoerer MP, Hicks P, Liang J, Ruthel G, Berry CT, Freedman BD, Sagum CA, Bedford MT, Sidhu SS, Sudol M, Harty RN.

Diseases. 2018 Jul 13;6(3). pii: E64. doi: 10.3390/diseases6030064.

20.

Host IQGAP1 and Ebola virus VP40 interactions facilitate virus-like particle egress.

Lu J, Qu Y, Liu Y, Jambusaria R, Han Z, Ruthel G, Freedman BD, Harty RN.

J Virol. 2013 Jul;87(13):7777-80. doi: 10.1128/JVI.00470-13. Epub 2013 May 1.

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