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Items: 1 to 20 of 100

1.

A mechanism of cellular resistance to drugs that interfere with microtubule assembly.

Cabral FR, Brady RC, Schibler MJ.

Ann N Y Acad Sci. 1986;466:745-56. No abstract available.

PMID:
2873781
2.

Amino acid substitutions at proline 220 of beta-tubulin confer resistance to paclitaxel and colcemid.

Yin S, Cabral F, Veeraraghavan S.

Mol Cancer Ther. 2007 Oct;6(10):2798-806.

3.

Paclitaxel resistance in cells with reduced beta-tubulin.

Wang Y, Cabral F.

Biochim Biophys Acta. 2005 Jun 30;1744(2):245-55. Epub 2005 Jan 5.

4.

Mutations in alpha- and beta-tubulin that stabilize microtubules and confer resistance to colcemid and vinblastine.

Hari M, Wang Y, Veeraraghavan S, Cabral F.

Mol Cancer Ther. 2003 Jul;2(7):597-605.

5.

Microtubules in colcemid-resistant mutants of CHO cells.

Connolly JA, Kalnins VI, Ling V.

Exp Cell Res. 1981 Mar;132(1):147-55. No abstract available.

PMID:
7009175
6.

Overexpression of mitotic centromere-associated Kinesin stimulates microtubule detachment and confers resistance to paclitaxel.

Ganguly A, Yang H, Cabral F.

Mol Cancer Ther. 2011 Jun;10(6):929-37. doi: 10.1158/1535-7163.MCT-10-1109. Epub 2011 Apr 6.

7.
8.

Tubulin assembly sites and the organization of microtubule arrays in mammalian cells.

Brenner SL, Brinkley BR.

Cold Spring Harb Symp Quant Biol. 1982;46 Pt 1:241-54. No abstract available.

PMID:
6125294
9.

Structural and functional alterations in microtubule protein from Chinese hamster ovary cell mutants.

Keates RA, Sarangi F, Ling V.

Proc Natl Acad Sci U S A. 1981 Sep;78(9):5638-42.

10.

Human mutations that confer paclitaxel resistance.

Yin S, Bhattacharya R, Cabral F.

Mol Cancer Ther. 2010 Feb;9(2):327-35. doi: 10.1158/1535-7163.MCT-09-0674. Epub 2010 Jan 26.

11.

Molecular basis for class V beta-tubulin effects on microtubule assembly and paclitaxel resistance.

Bhattacharya R, Cabral F.

J Biol Chem. 2009 May 8;284(19):13023-32. doi: 10.1074/jbc.M900167200. Epub 2009 Mar 12.

12.

Isolation of a taxol-resistant Chinese hamster ovary cell mutant that has an alteration in alpha-tubulin.

Cabral F, Abraham I, Gottesman MM.

Proc Natl Acad Sci U S A. 1981 Jul;78(7):4388-91.

13.
14.

Intra-allelic suppression of a mutation that stabilizes microtubules and confers resistance to colcemid.

Wang Y, Veeraraghavan S, Cabral F.

Biochemistry. 2004 Jul 20;43(28):8965-73.

PMID:
15248754
15.

CHO mutants resistant to colchicine, colcemid or griseofulvin have an altered beta-tubulin.

Cabral F, Sobel ME, Gottesman MM.

Cell. 1980 May;20(1):29-36.

PMID:
7388944
16.

Mutations at leucine 215 of beta-tubulin affect paclitaxel sensitivity by two distinct mechanisms.

Wang Y, Yin S, Blade K, Cooper G, Menick DR, Cabral F.

Biochemistry. 2006 Jan 10;45(1):185-94.

PMID:
16388594
17.

Paclitaxel-dependent mutants have severely reduced microtubule assembly and reduced tubulin synthesis.

Barlow SB, Gonzalez-Garay ML, Cabral F.

J Cell Sci. 2002 Sep 1;115(Pt 17):3469-78.

18.

Megakaryocyte lineage-specific class VI β-tubulin suppresses microtubule dynamics, fragments microtubules, and blocks cell division.

Yang H, Ganguly A, Yin S, Cabral F.

Cytoskeleton (Hoboken). 2011 Mar;68(3):175-87. doi: 10.1002/cm.20503.

20.

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