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Items: 1 to 20 of 111

1.

ANGPTL4 promotes bile acid absorption during taurocholic acid supplementation via a mechanism dependent on the gut microbiota.

Janssen AWF, Dijk W, Boekhorst J, Kuipers F, Groen AK, Lukovac S, Hooiveld GJEJ, Kersten S.

Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Oct;1862(10 Pt A):1056-1067. doi: 10.1016/j.bbalip.2017.07.005. Epub 2017 Jul 18.

PMID:
28733267
2.

Inhibition of intestinal bile acid absorption improves cholestatic liver and bile duct injury in a mouse model of sclerosing cholangitis.

Baghdasaryan A, Fuchs CD, Österreicher CH, Lemberger UJ, Halilbasic E, Påhlman I, Graffner H, Krones E, Fickert P, Wahlström A, Ståhlman M, Paumgartner G, Marschall HU, Trauner M.

J Hepatol. 2016 Mar;64(3):674-81. doi: 10.1016/j.jhep.2015.10.024. Epub 2015 Oct 31.

3.

Gut microbiota inhibit Asbt-dependent intestinal bile acid reabsorption via Gata4.

Out C, Patankar JV, Doktorova M, Boesjes M, Bos T, de Boer S, Havinga R, Wolters H, Boverhof R, van Dijk TH, Smoczek A, Bleich A, Sachdev V, Kratky D, Kuipers F, Verkade HJ, Groen AK.

J Hepatol. 2015 Sep;63(3):697-704. doi: 10.1016/j.jhep.2015.04.030. Epub 2015 May 27.

4.

Orally Administered Berberine Modulates Hepatic Lipid Metabolism by Altering Microbial Bile Acid Metabolism and the Intestinal FXR Signaling Pathway.

Sun R, Yang N, Kong B, Cao B, Feng D, Yu X, Ge C, Huang J, Shen J, Wang P, Feng S, Fei F, Guo J, He J, Aa N, Chen Q, Pan Y, Schumacher JD, Yang CS, Guo GL, Aa J, Wang G.

Mol Pharmacol. 2017 Feb;91(2):110-122. doi: 10.1124/mol.116.106617. Epub 2016 Dec 8.

5.

Resveratrol Attenuates Trimethylamine-N-Oxide (TMAO)-Induced Atherosclerosis by Regulating TMAO Synthesis and Bile Acid Metabolism via Remodeling of the Gut Microbiota.

Chen ML, Yi L, Zhang Y, Zhou X, Ran L, Yang J, Zhu JD, Zhang QY, Mi MT.

MBio. 2016 Apr 5;7(2):e02210-15. doi: 10.1128/mBio.02210-15.

6.

Inhibition of intestinal bile acid transporter Slc10a2 improves triglyceride metabolism and normalizes elevated plasma glucose levels in mice.

Lundåsen T, Andersson EM, Snaith M, Lindmark H, Lundberg J, Östlund-Lindqvist AM, Angelin B, Rudling M.

PLoS One. 2012;7(5):e37787. doi: 10.1371/journal.pone.0037787. Epub 2012 May 25.

7.

The ileal lipid binding protein is required for efficient absorption and transport of bile acids in the distal portion of the murine small intestine.

Praslickova D, Torchia EC, Sugiyama MG, Magrane EJ, Zwicker BL, Kolodzieyski L, Agellon LB.

PLoS One. 2012;7(12):e50810. doi: 10.1371/journal.pone.0050810. Epub 2012 Dec 10.

8.

Inhibition of ileal bile acid uptake protects against nonalcoholic fatty liver disease in high-fat diet-fed mice.

Rao A, Kosters A, Mells JE, Zhang W, Setchell KD, Amanso AM, Wynn GM, Xu T, Keller BT, Yin H, Banton S, Jones DP, Wu H, Dawson PA, Karpen SJ.

Sci Transl Med. 2016 Sep 21;8(357):357ra122. doi: 10.1126/scitranslmed.aaf4823.

9.

Cholesterol feeding prevents hepatic accumulation of bile acids in cholic acid-fed farnesoid X receptor (FXR)-null mice: FXR-independent suppression of intestinal bile acid absorption.

Miyata M, Matsuda Y, Nomoto M, Takamatsu Y, Sato N, Hamatsu M, Dawson PA, Gonzalez FJ, Yamazoe Y.

Drug Metab Dispos. 2009 Feb;37(2):338-44. doi: 10.1124/dmd.108.022590. Epub 2008 Nov 6.

10.
11.

Loss of angiopoietin-like 4 (ANGPTL4) in mice with diet-induced obesity uncouples visceral obesity from glucose intolerance partly via the gut microbiota.

Janssen AWF, Katiraei S, Bartosinska B, Eberhard D, Willems van Dijk K, Kersten S.

Diabetologia. 2018 Jun;61(6):1447-1458. doi: 10.1007/s00125-018-4583-5. Epub 2018 Mar 3.

PMID:
29502266
12.

Antibacterial drug treatment increases intestinal bile acid absorption via elevated levels of ileal apical sodium-dependent bile acid transporter but not organic solute transporter α protein.

Miyata M, Hayashi K, Yamakawa H, Yamazoe Y, Yoshinari K.

Biol Pharm Bull. 2015;38(3):493-6. doi: 10.1248/bpb.b14-00640. Epub 2014 Dec 27.

13.

Targeting the gut microbiota with inulin-type fructans: preclinical demonstration of a novel approach in the management of endothelial dysfunction.

Catry E, Bindels LB, Tailleux A, Lestavel S, Neyrinck AM, Goossens JF, Lobysheva I, Plovier H, Essaghir A, Demoulin JB, Bouzin C, Pachikian BD, Cani PD, Staels B, Dessy C, Delzenne NM.

Gut. 2018 Feb;67(2):271-283. doi: 10.1136/gutjnl-2016-313316. Epub 2017 Apr 4.

14.

Effects of Ala substitution for conserved Cys residues in mouse ileal and hepatic Na+-dependent bile acid transporters.

Saeki T, Munetaka Y, Ueda K, Iwami K, Kanamoto R.

Biosci Biotechnol Biochem. 2007 Aug;71(8):1865-72. Epub 2007 Aug 7.

15.

Impaired uptake of conjugated bile acids and hepatitis b virus pres1-binding in na(+) -taurocholate cotransporting polypeptide knockout mice.

Slijepcevic D, Kaufman C, Wichers CG, Gilglioni EH, Lempp FA, Duijst S, de Waart DR, Elferink RP, Mier W, Stieger B, Beuers U, Urban S, van de Graaf SF.

Hepatology. 2015 Jul;62(1):207-19. doi: 10.1002/hep.27694. Epub 2015 May 8.

16.

Inhibition of ileal apical but not basolateral bile acid transport reduces atherosclerosis in apoE⁻/⁻ mice.

Lan T, Haywood J, Dawson PA.

Atherosclerosis. 2013 Aug;229(2):374-80. doi: 10.1016/j.atherosclerosis.2013.05.017. Epub 2013 May 28.

17.

Ileal apical sodium-dependent bile acid transporter protein levels are down-regulated through ubiquitin-dependent protein degradation induced by bile acids.

Miyata M, Yamakawa H, Hayashi K, Kuribayashi H, Yamazoe Y, Yoshinari K.

Eur J Pharmacol. 2013 Aug 15;714(1-3):507-14. doi: 10.1016/j.ejphar.2013.06.036. Epub 2013 Jul 18.

PMID:
23872411
18.

Effect of various antibiotics on modulation of intestinal microbiota and bile acid profile in mice.

Zhang Y, Limaye PB, Renaud HJ, Klaassen CD.

Toxicol Appl Pharmacol. 2014 Jun 1;277(2):138-45. doi: 10.1016/j.taap.2014.03.009. Epub 2014 Mar 20.

19.

Muricholic bile acids are potent regulators of bile acid synthesis via a positive feedback mechanism.

Hu X, Bonde Y, Eggertsen G, Rudling M.

J Intern Med. 2014 Jan;275(1):27-38. doi: 10.1111/joim.12140. Epub 2013 Oct 11. Erratum in: J Intern Med. 2015 Jul;278(1):97.

20.

Editor's Highlight: Clofibrate Decreases Bile Acids in Livers of Male Mice by Increasing Biliary Bile Acid Excretion in a PPARα-Dependent Manner.

Zhang Y, Lickteig AJ, Csanaky IL, Klaassen CD.

Toxicol Sci. 2017 Dec 1;160(2):351-360. doi: 10.1093/toxsci/kfx191.

PMID:
28973556

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