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Items: 1 to 20 of 132

1.

Activation of the B-cell receptor successively activates NF-κB and STAT3 in chronic lymphocytic leukemia cells.

Rozovski U, Harris DM, Li P, Liu Z, Jain P, Veletic I, Ferrajoli A, Burger J, Thompson P, Jain N, Wierda W, Keating MJ, Estrov Z.

Int J Cancer. 2017 Nov 15;141(10):2076-2081. doi: 10.1002/ijc.30892. Epub 2017 Aug 4.

PMID:
28722170
2.

Stimulation of the B-cell receptor activates the JAK2/STAT3 signaling pathway in chronic lymphocytic leukemia cells.

Rozovski U, Wu JY, Harris DM, Liu Z, Li P, Hazan-Halevy I, Ferrajoli A, Burger JA, O'Brien S, Jain N, Verstovsek S, Wierda WG, Keating MJ, Estrov Z.

Blood. 2014 Jun 12;123(24):3797-802. doi: 10.1182/blood-2013-10-534073. Epub 2014 Apr 28.

3.

STAT3 and NF-κB cooperatively control in vitro spontaneous apoptosis and poor chemo-responsiveness in patients with chronic lymphocytic leukemia.

Liu FT, Jia L, Wang P, Wang H, Farren TW, Agrawal SG.

Oncotarget. 2016 May 31;7(22):32031-45. doi: 10.18632/oncotarget.8672.

4.

JAK2 inhibitor blocks the inflammation and growth of esophageal squamous cell carcinoma in vitro through the JAK/STAT3 pathway.

Fang J, Chu L, Li C, Chen Y, Hu F, Zhang X, Zhao H, Liu Z, Xu Q.

Oncol Rep. 2015 Jan;33(1):494-502. doi: 10.3892/or.2014.3609. Epub 2014 Nov 14.

PMID:
25405520
5.

Sustained signaling through the B-cell receptor induces Mcl-1 and promotes survival of chronic lymphocytic leukemia B cells.

Petlickovski A, Laurenti L, Li X, Marietti S, Chiusolo P, Sica S, Leone G, Efremov DG.

Blood. 2005 Jun 15;105(12):4820-7. Epub 2005 Feb 22.

6.

STAT-3 activates NF-kappaB in chronic lymphocytic leukemia cells.

Liu Z, Hazan-Halevy I, Harris DM, Li P, Ferrajoli A, Faderl S, Keating MJ, Estrov Z.

Mol Cancer Res. 2011 Apr;9(4):507-15. doi: 10.1158/1541-7786.MCR-10-0559. Epub 2011 Mar 1.

7.

An RNA-binding protein alphaCP-1 is involved in the STAT3-mediated suppression of NF-kappaB transcriptional activity.

Nishinakamura H, Minoda Y, Saeki K, Koga K, Takaesu G, Onodera M, Yoshimura A, Kobayashi T.

Int Immunol. 2007 May;19(5):609-19. Epub 2007 Mar 22.

PMID:
17383969
8.

Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765.

Herman SE, Gordon AL, Hertlein E, Ramanunni A, Zhang X, Jaglowski S, Flynn J, Jones J, Blum KA, Buggy JJ, Hamdy A, Johnson AJ, Byrd JC.

Blood. 2011 Jun 9;117(23):6287-96. doi: 10.1182/blood-2011-01-328484. Epub 2011 Mar 21.

9.

Activation of the NF-κB pathway by the STAT3 inhibitor JSI-124 in human glioblastoma cells.

McFarland BC, Gray GK, Nozell SE, Hong SW, Benveniste EN.

Mol Cancer Res. 2013 May;11(5):494-505. doi: 10.1158/1541-7786.MCR-12-0528. Epub 2013 Feb 5.

10.
11.

The lymph node microenvironment promotes B-cell receptor signaling, NF-kappaB activation, and tumor proliferation in chronic lymphocytic leukemia.

Herishanu Y, Pérez-Galán P, Liu D, Biancotto A, Pittaluga S, Vire B, Gibellini F, Njuguna N, Lee E, Stennett L, Raghavachari N, Liu P, McCoy JP, Raffeld M, Stetler-Stevenson M, Yuan C, Sherry R, Arthur DC, Maric I, White T, Marti GE, Munson P, Wilson WH, Wiestner A.

Blood. 2011 Jan 13;117(2):563-74. doi: 10.1182/blood-2010-05-284984. Epub 2010 Oct 12.

13.
14.

Cooperative signaling through the signal transducer and activator of transcription 3 and nuclear factor-{kappa}B pathways in subtypes of diffuse large B-cell lymphoma.

Lam LT, Wright G, Davis RE, Lenz G, Farinha P, Dang L, Chan JW, Rosenwald A, Gascoyne RD, Staudt LM.

Blood. 2008 Apr 1;111(7):3701-13. Epub 2007 Dec 26.

15.

Expression of ZAP70 in chronic lymphocytic leukaemia activates NF-κB signalling.

Pede V, Rombout A, Vermeire J, Naessens E, Vanderstraeten H, Philippé J, Verhasselt B.

Br J Haematol. 2013 Dec;163(5):621-30. doi: 10.1111/bjh.12588. Epub 2013 Oct 8.

PMID:
24219331
16.

2-Methoxystypandrone inhibits signal transducer and activator of transcription 3 and nuclear factor-κB signaling by inhibiting Janus kinase 2 and IκB kinase.

Kuang S, Qi C, Liu J, Sun X, Zhang Q, Sima Z, Liu J, Li W, Yu Q.

Cancer Sci. 2014 Apr;105(4):473-80. doi: 10.1111/cas.12359. Epub 2014 Mar 3.

17.

Cytokine modulation of nuclear factor-kappaB activity in B-chronic lymphocytic leukemia.

Zaninoni A, Imperiali FG, Pasquini C, Zanella A, Barcellini W.

Exp Hematol. 2003 Mar;31(3):185-90.

PMID:
12644014
18.

Engagement of the B-cell antigen receptor activates STAT through Lyn in a Jak-independent pathway.

Wang L, Kurosaki T, Corey SJ.

Oncogene. 2007 May 3;26(20):2851-9. Epub 2006 Dec 4.

PMID:
17146444
19.

HB-EGF induces delayed STAT3 activation via NF-kappaB mediated IL-6 secretion in vascular smooth muscle cell.

Lee KS, Park JH, Lee S, Lim HJ, Choi HE, Park HY.

Biochim Biophys Acta. 2007 Nov;1773(11):1637-44. Epub 2007 Jul 17.

20.

Hypoxia-induced SOCS3 is limiting STAT3 phosphorylation and NF-κB activation in congenital heart disease.

Gu Q, Kong Y, Yu ZB, Bai L, Xiao YB.

Biochimie. 2011 May;93(5):909-20. doi: 10.1016/j.biochi.2011.02.009. Epub 2011 Feb 24.

PMID:
21354254

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