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Items: 1 to 20 of 114


Hyperthermia-enhanced targeted drug delivery using magnetic resonance-guided focussed ultrasound: a pre-clinical study in a genetic model of pancreatic cancer.

Farr N, Wang YN, D'Andrea S, Starr F, Partanen A, Gravelle KM, McCune JS, Risler LJ, Whang SG, Chang A, Hingorani SR, Lee D, Hwang JH.

Int J Hyperthermia. 2018 May;34(3):284-291. doi: 10.1080/02656736.2017.1336675. Epub 2017 Jul 17.


Image-guided drug delivery with magnetic resonance guided high intensity focused ultrasound and temperature sensitive liposomes in a rabbit Vx2 tumor model.

Ranjan A, Jacobs GC, Woods DL, Negussie AH, Partanen A, Yarmolenko PS, Gacchina CE, Sharma KV, Frenkel V, Wood BJ, Dreher MR.

J Control Release. 2012 Mar 28;158(3):487-94. doi: 10.1016/j.jconrel.2011.12.011. Epub 2011 Dec 21.


Focused Ultrasound Hyperthermia Mediated Drug Delivery Using Thermosensitive Liposomes and Visualized With in vivo Two-Photon Microscopy.

Santos MA, Goertz DE, Hynynen K.

Theranostics. 2017 Jul 7;7(10):2718-2731. doi: 10.7150/thno.19662. eCollection 2017.


Thermal combination therapies for local drug delivery by magnetic resonance-guided high-intensity focused ultrasound.

Hijnen N, Kneepkens E, de Smet M, Langereis S, Heijman E, Grüll H.

Proc Natl Acad Sci U S A. 2017 Jun 13;114(24):E4802-E4811. doi: 10.1073/pnas.1700790114. Epub 2017 May 31.


Longer heating duration increases localized doxorubicin deposition and therapeutic index in Vx2 tumors using MR-HIFU mild hyperthermia and thermosensitive liposomal doxorubicin.

Bing C, Patel P, Staruch RM, Shaikh S, Nofiele J, Wodzak Staruch M, Szczepanski D, Williams NS, Laetsch T, Chopra R.

Int J Hyperthermia. 2019;36(1):196-203. doi: 10.1080/02656736.2018.1550815. Epub 2018 Dec 12.


Interleaved Mapping of Temperature and Longitudinal Relaxation Rate to Monitor Drug Delivery During Magnetic Resonance-Guided High-Intensity Focused Ultrasound-Induced Hyperthermia.

Kneepkens E, Heijman E, Keupp J, Weiss S, Nicolay K, Grüll H.

Invest Radiol. 2017 Oct;52(10):620-630. doi: 10.1097/RLI.0000000000000392.


Mild hyperthermia with magnetic resonance-guided high-intensity focused ultrasound for applications in drug delivery.

Partanen A, Yarmolenko PS, Viitala A, Appanaboyina S, Haemmerich D, Ranjan A, Jacobs G, Woods D, Enholm J, Wood BJ, Dreher MR.

Int J Hyperthermia. 2012;28(4):320-36. doi: 10.3109/02656736.2012.680173. Erratum in: Int J Hyperthermia. 2012;28(5):473.


Synthesis and characterisation of ultrasound imageable heat-sensitive liposomes for HIFU therapy.

Maples D, McLean K, Sahoo K, Newhardt R, Venkatesan P, Wood B, Ranjan A.

Int J Hyperthermia. 2015;31(6):674-85. doi: 10.3109/02656736.2015.1057622. Epub 2015 Jul 17.


MRI Monitoring of Tumor-Selective Anticancer Drug Delivery with Stable Thermosensitive Liposomes Triggered by High-Intensity Focused Ultrasound.

Kim HR, You DG, Park SJ, Choi KS, Um W, Kim JH, Park JH, Kim YS.

Mol Pharm. 2016 May 2;13(5):1528-39. doi: 10.1021/acs.molpharmaceut.6b00013. Epub 2016 Mar 29.


Hyperthermia-mediated doxorubicin release from thermosensitive liposomes using MR-HIFU: therapeutic effect in rabbit Vx2 tumours.

Staruch RM, Hynynen K, Chopra R.

Int J Hyperthermia. 2015 Mar;31(2):118-33. doi: 10.3109/02656736.2014.992483. Epub 2015 Jan 13.


Sequential HIFU heating and nanobubble encapsulation provide efficient drug penetration from stealth and temperature sensitive liposomes in colon cancer.

VanOsdol J, Ektate K, Ramasamy S, Maples D, Collins W, Malayer J, Ranjan A.

J Control Release. 2017 Feb 10;247:55-63. doi: 10.1016/j.jconrel.2016.12.033. Epub 2016 Dec 30.


Hyperthermia-triggered drug delivery from iRGD-modified temperature-sensitive liposomes enhances the anti-tumor efficacy using high intensity focused ultrasound.

Deng Z, Xiao Y, Pan M, Li F, Duan W, Meng L, Liu X, Yan F, Zheng H.

J Control Release. 2016 Dec 10;243:333-341. doi: 10.1016/j.jconrel.2016.10.030. Epub 2016 Oct 28.


Mathematical spatio-temporal model of drug delivery from low temperature sensitive liposomes during radiofrequency tumour ablation.

Gasselhuber A, Dreher MR, Negussie A, Wood BJ, Rattay F, Haemmerich D.

Int J Hyperthermia. 2010;26(5):499-513. doi: 10.3109/02656731003623590.


Targeted antibiotic delivery using low temperature-sensitive liposomes and magnetic resonance-guided high-intensity focused ultrasound hyperthermia.

Wardlow R, Bing C, VanOsdol J, Maples D, Ladouceur-Wodzak M, Harbeson M, Nofiele J, Staruch R, Ramachandran A, Malayer J, Chopra R, Ranjan A.

Int J Hyperthermia. 2016 May;32(3):254-64. doi: 10.3109/02656736.2015.1134818. Epub 2016 Feb 18.


Targeted drug delivery by high intensity focused ultrasound mediated hyperthermia combined with temperature-sensitive liposomes: computational modelling and preliminary in vivovalidation.

Gasselhuber A, Dreher MR, Partanen A, Yarmolenko PS, Woods D, Wood BJ, Haemmerich D.

Int J Hyperthermia. 2012;28(4):337-48. doi: 10.3109/02656736.2012.677930.


Improvement of Antitumor Efficacy by Combination of Thermosensitive Liposome with High-Intensity Focused Ultrasound.

Cha JM, You DG, Choi EJ, Park SJ, Um W, Jeon J, Kim K, Kwon IC, Park JC, Kim HR, Park JH.

J Biomed Nanotechnol. 2016 Sep;12(9):1724-33.


Hyperthermia sensitization and proton beam triggered liposomal drug release for targeted tumor therapy.

Fernando R, Maples D, Senavirathna LK, Zheng Y, Polf JC, Benton ER, Bartels KE, Piao D, Ranjan A.

Pharm Res. 2014 Nov;31(11):3120-6. doi: 10.1007/s11095-014-1404-5. Epub 2014 May 23.


Novel temperature-triggered liposome with high stability: formulation, in vitro evaluation, and in vivo study combined with high-intensity focused ultrasound (HIFU).

Park SM, Kim MS, Park SJ, Park ES, Choi KS, Kim YS, Kim HR.

J Control Release. 2013 Sep 28;170(3):373-9. doi: 10.1016/j.jconrel.2013.06.003. Epub 2013 Jun 13.


Magnetic resonance imaging of temperature-sensitive liposome release: drug dose painting and antitumor effects.

Ponce AM, Viglianti BL, Yu D, Yarmolenko PS, Michelich CR, Woo J, Bally MB, Dewhirst MW.

J Natl Cancer Inst. 2007 Jan 3;99(1):53-63.


Biodistribution and Efficacy of Low Temperature-Sensitive Liposome Encapsulated Docetaxel Combined with Mild Hyperthermia in a Mouse Model of Prostate Cancer.

Ranjan A, Benjamin CJ, Negussie AH, Chokshi S, Chung PH, Volkin D, Yeram N, Linehan WM, Dreher MR, Pinto PA, Wood BJ.

Pharm Res. 2016 Oct;33(10):2459-69. doi: 10.1007/s11095-016-1971-8. Epub 2016 Jun 24.


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