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Epidermal growth factor receptor intron-1 CA repeat polymorphism on protein expression and clinical outcome in Taiwanese oral squamous cell carcinoma.

Huang SF, Chien HT, Chuang WY, Lai CH, Cheng SD, Liao CT, Wang HM.

Sci Rep. 2017 Jul 10;7(1):4963. doi: 10.1038/s41598-017-04954-5.


Relationship between epidermal growth factor receptor gene copy number and protein expression in oral cavity squamous cell carcinoma.

Huang SF, Cheng SD, Chien HT, Liao CT, Chen IH, Wang HM, Chuang WY, Wang CY, Hsieh LL.

Oral Oncol. 2012 Jan;48(1):67-72. doi: 10.1016/j.oraloncology.2011.06.511. Epub 2011 Aug 9.


Lack of evidence for prognostic value of epidermal growth factor receptor intron-1 CA repeats for oral carcinomas.

Precht C, Blessmann M, Kluwe L, Scheld T, Schön G, Henningsen A, Pflug C, Smeets R, Heiland M, Gröbe A.

Eur J Oral Sci. 2017 Apr;125(2):95-101. doi: 10.1111/eos.12333. Epub 2017 Feb 2.


EGFR copy number alterations in primary tumors, metastatic lymph nodes, and recurrent and multiple primary tumors in oral cavity squamous cell carcinoma.

Huang SF, Chien HT, Cheng SD, Chuang WY, Liao CT, Wang HM.

BMC Cancer. 2017 Aug 30;17(1):592. doi: 10.1186/s12885-017-3586-9.


Epidermal growth factor receptor expression and gene copy number in the risk of oral cancer.

Taoudi Benchekroun M, Saintigny P, Thomas SM, El-Naggar AK, Papadimitrakopoulou V, Ren H, Lang W, Fan YH, Huang J, Feng L, Lee JJ, Kim ES, Hong WK, Johnson FM, Grandis JR, Mao L.

Cancer Prev Res (Phila). 2010 Jul;3(7):800-9. doi: 10.1158/1940-6207.CAPR-09-0163. Epub 2010 Jun 22.


The status of EGFR CA SSR1 is a potential prognostic factor for patients with oral squamous cell carcinoma.

Lin YL, Wang WY, Lin JC, Wong YK, Chien YC.

Oral Oncol. 2011 Jun;47(6):482-6. doi: 10.1016/j.oraloncology.2010.08.006. Epub 2011 May 6.


Epidermal growth factor receptor intron-1 polymorphism predicts gefitinib outcome in advanced non-small cell lung cancer.

Tiseo M, Capelletti M, De Palma G, Franciosi V, Cavazzoni A, Mozzoni P, Alfieri RR, Goldoni M, Galetti M, Bortesi B, Bozzetti C, Loprevite M, Boni L, Camisa R, Rindi G, Petronini PG, Ardizzoni A.

J Thorac Oncol. 2008 Oct;3(10):1104-11. doi: 10.1097/JTO.0b013e3181861d67.


Association of epidermal growth factor receptor (EGFR) gene copy number amplification with neck lymph node metastasis in areca-associated oral carcinomas.

Chiang WF, Liu SY, Yen CY, Lin CN, Chen YC, Lin SC, Chang KW.

Oral Oncol. 2008 Mar;44(3):270-6. Epub 2007 Apr 30.


EGFR protein overexpression and mutation in areca quid-associated oral cavity squamous cell carcinoma in Taiwan.

Huang SF, Chuang WY, Chen IH, Liao CT, Wang HM, Hsieh LL.

Head Neck. 2009 Aug;31(8):1068-77. doi: 10.1002/hed.21067.


Epidermal growth factor receptor gene copy number aberration at the primary tumour is significantly associated with extracapsular spread in oral cancer.

Michikawa C, Uzawa N, Sato H, Ohyama Y, Okada N, Amagasa T.

Br J Cancer. 2011 Mar 1;104(5):850-5. doi: 10.1038/bjc.2011.22. Epub 2011 Feb 8.


Inverse relationship between the length of the EGFR CA repeat polymorphism in lung carcinoma and protein expression of EGFR in the carcinoma.

Suzuki M, Kageyama S, Shinmura K, Okudela K, Bunai T, Nagura K, Igarashi H, Kiyose S, Mori H, Tao H, Goto M, Takamochi K, Mochizuki T, Suzuki K, Ohashi R, Ogawa H, Yamada T, Niwa H, Tsuneyoshi T, Sugimura H.

J Surg Oncol. 2008 Nov 1;98(6):457-61. doi: 10.1002/jso.21130.


Exon 19 of EGFR mutation in relation to the CA-repeat polymorphism in intron 1.

Sueoka-Aragane N, Imai K, Komiya K, Sato A, Tomimasu R, Hisatomi T, Sakuragi T, Mitsuoka M, Hayashi S, Nakachi K, Sueoka E.

Cancer Sci. 2008 Jun;99(6):1180-7. doi: 10.1111/j.1349-7006.2008.00804.x. Epub 2008 Apr 14.


EGFR intron-1 CA repeat polymorphism is a predictor of relapse and survival in complete resected only surgically treated esophageal cancer.

Vashist YK, Trump F, Gebauer F, Kutup A, Güngör C, Kalinin V, Muddasar R, Vettorazzi E, Yekebas EF, Brandt B, Pantel K, Izbicki JR.

Target Oncol. 2014 Mar;9(1):43-52. doi: 10.1007/s11523-013-0260-2. Epub 2013 Feb 2.


Clinical Implications of FADD Gene Amplification and Protein Overexpression in Taiwanese Oral Cavity Squamous Cell Carcinomas.

Chien HT, Cheng SD, Chuang WY, Liao CT, Wang HM, Huang SF.

PLoS One. 2016 Oct 20;11(10):e0164870. doi: 10.1371/journal.pone.0164870. eCollection 2016.


Combined cytoplasmic and membranous EGFR and p53 overexpression is a poor prognostic marker in early stage oral squamous cell carcinoma.

Monteiro LS, Diniz-Freitas M, Garcia-Caballero T, Warnakulasuriya S, Forteza J, Fraga M.

J Oral Pathol Med. 2012 Aug;41(7):559-67. doi: 10.1111/j.1600-0714.2012.01142.x. Epub 2012 Mar 14.


Cathepsin K associates with lymph node metastasis and poor prognosis in oral squamous cell carcinoma.

Leusink FK, Koudounarakis E, Frank MH, Koole R, van Diest PJ, Willems SM.

BMC Cancer. 2018 Apr 5;18(1):385. doi: 10.1186/s12885-018-4315-8.


Epidermal growth factor receptor copy number in potentially malignant oral disorders and oral squamous cell carcinoma: a short communication and preliminary study.

Bagan JV, Mata-Roig M, Cortio-Gimeno J, Murillo-Cortes J, Hens-Aumente E, Poveda-Roda R, Bagan L.

J Oral Pathol Med. 2012 Oct;41(9):662-6. doi: 10.1111/j.1600-0714.2012.01137.x. Epub 2012 Mar 14.


No association between dinucleotide repeat polymorphism in intron 1 of the epidermal growth factor receptor gene EGFR and risk of lung cancer.

Lee SJ, Kim KM, Chae MH, Lee WK, Kam S, Cha SI, Han HS, Kim CH, Kang YM, Han SB, Park JY.

Cancer Genet Cytogenet. 2007 Jan 1;172(1):29-32.


Epidermal growth factor receptor intron 1 CA dinucleotide repeat polymorphism and survival of advanced gastric cancer patients treated with cetuximab plus modified FOLFOX6.

Han SW, Oh DY, Im SA, Park SR, Lee KW, Song HS, Lee NS, Lee KH, Choi IS, Lee MH, Kim MA, Kim WH, Bang YJ, Kim TY.

Cancer Sci. 2010 Mar;101(3):793-9. doi: 10.1111/j.1349-7006.2009.01447.x. Epub 2009 Nov 23.


Cyclin D1 overexpression and poor clinical outcomes in Taiwanese oral cavity squamous cell carcinoma.

Huang SF, Cheng SD, Chuang WY, Chen IH, Liao CT, Wang HM, Hsieh LL.

World J Surg Oncol. 2012 Feb 16;10:40. doi: 10.1186/1477-7819-10-40.

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