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Items: 1 to 20 of 99

1.

Patient-derived Xenografts from Colorectal Carcinoma: A Temporal and Hierarchical Study of Murine Stromal Cell Replacement.

Chao C, Widen SG, Wood TG, Zatarain JR, Johnson P, Gajjar A, Gomez G, Qiu S, Thompson J, Spratt H, Hellmich MR.

Anticancer Res. 2017 Jul;37(7):3405-3412.

2.

Murine stroma adopts a human-like metabolic phenotype in the PDX model of colorectal cancer and liver metastases.

Blomme A, Van Simaeys G, Doumont G, Costanza B, Bellier J, Otaka Y, Sherer F, Lovinfosse P, Boutry S, Palacios AP, De Pauw E, Hirano T, Yokobori T, Hustinx R, Bellahcène A, Delvenne P, Detry O, Goldman S, Nishiyama M, Castronovo V, Turtoi A.

Oncogene. 2018 Mar;37(9):1237-1250. doi: 10.1038/s41388-017-0018-x. Epub 2017 Dec 15.

PMID:
29242606
3.

Colorectal cancer patient-derived xenografted tumors maintain characteristic features of the original tumors.

Cho YB, Hong HK, Choi YL, Oh E, Joo KM, Jin J, Nam DH, Ko YH, Lee WY.

J Surg Res. 2014 Apr;187(2):502-9. doi: 10.1016/j.jss.2013.11.010. Epub 2013 Nov 15.

PMID:
24332554
4.

A short-term colorectal cancer sphere culture as a relevant tool for human cancer biology investigation.

Weiswald LB, Richon S, Massonnet G, Guinebretière JM, Vacher S, Laurendeau I, Cottu P, Marangoni E, Nemati F, Validire P, Bellet D, Bièche I, Dangles-Marie V.

Br J Cancer. 2013 Apr 30;108(8):1720-31. doi: 10.1038/bjc.2013.132. Epub 2013 Mar 28.

5.

The critical roles of tumor-initiating cells and the lymph node stromal microenvironment in human colorectal cancer extranodal metastasis using a unique humanized orthotopic mouse model.

Margolin DA, Myers T, Zhang X, Bertoni DM, Reuter BA, Obokhare I, Borgovan T, Grimes C, Green H, Driscoll T, Lee CG, Davis NK, Li L.

FASEB J. 2015 Aug;29(8):3571-81. doi: 10.1096/fj.14-268938. Epub 2015 May 11.

6.

Patient-Derived Xenograft Models of Colorectal Cancer: Procedures for Engraftment and Propagation.

Burgenske DM, Monsma DJ, MacKeigan JP.

Methods Mol Biol. 2018;1765:307-314. doi: 10.1007/978-1-4939-7765-9_20.

PMID:
29589317
7.

Stromal contribution to the colorectal cancer transcriptome.

Isella C, Terrasi A, Bellomo SE, Petti C, Galatola G, Muratore A, Mellano A, Senetta R, Cassenti A, Sonetto C, Inghirami G, Trusolino L, Fekete Z, De Ridder M, Cassoni P, Storme G, Bertotti A, Medico E.

Nat Genet. 2015 Apr;47(4):312-9. doi: 10.1038/ng.3224. Epub 2015 Feb 23. Erratum in: Nat Genet. 2016 Sep 28;48(10):1296.

8.

Multipotent mesenchymal stromal cells promote tumor growth in distinct colorectal cancer cells by a β1-integrin-dependent mechanism.

Widder M, Lützkendorf J, Caysa H, Unverzagt S, Wickenhauser C, Benndorf RA, Schmoll HJ, Müller-Tidow C, Müller T, Müller LP.

Int J Cancer. 2016 Feb 15;138(4):964-75. doi: 10.1002/ijc.29844. Epub 2015 Oct 1.

9.

Capturing colorectal cancer inter-tumor heterogeneity in patient-derived xenograft (PDX) models.

Prasetyanti PR, van Hooff SR, van Herwaarden T, de Vries N, Kalloe K, Rodermond H, van Leersum R, de Jong JH, Franitza M, Nürnberg P, Todaro M, Stassi G, Medema JP.

Int J Cancer. 2019 Jan 15;144(2):366-371. doi: 10.1002/ijc.31767. Epub 2018 Oct 22.

10.

Differential transplantability of human endothelial cells in colorectal cancer and renal cell carcinoma primary xenografts.

Sanz L, Cuesta AM, Salas C, Corbacho C, Bellas C, Alvarez-Vallina L.

Lab Invest. 2009 Jan;89(1):91-7. doi: 10.1038/labinvest.2008.108. Epub 2008 Nov 10.

11.

Challenges in Stratifying the Molecular Variability of Patient-Derived Colon Tumor Xenografts.

Cybulska M, Olesinski T, Goryca K, Paczkowska K, Statkiewicz M, Kopczynski M, Grochowska A, Unrug-Bielawska K, Tyl-Bielicka A, Gajewska M, Mroz A, Dabrowska M, Karczmarski J, Paziewska A, Zając L, Bednarczyk M, Mikula M, Ostrowski J.

Biomed Res Int. 2018 Dec 19;2018:2954208. doi: 10.1155/2018/2954208. eCollection 2018.

12.

Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivo.

Wang H, Zhao G, Liu X, Sui A, Yang K, Yao R, Wang Z, Shi Q.

J Exp Clin Cancer Res. 2010 Sep 9;29:123. doi: 10.1186/1756-9966-29-123.

13.

E7080 (lenvatinib), a multi-targeted tyrosine kinase inhibitor, demonstrates antitumor activities against colorectal cancer xenografts.

Wiegering A, Korb D, Thalheimer A, Kämmerer U, Allmanritter J, Matthes N, Linnebacher M, Schlegel N, Klein I, Ergün S, Germer CT, Otto C.

Neoplasia. 2014 Nov 20;16(11):972-81. doi: 10.1016/j.neo.2014.09.008. eCollection 2014 Nov.

14.

The Colorectal Cancer Microenvironment: Strategies for Studying the Role of Cancer-Associated Fibroblasts.

Bhome R, Mellone M, Emo K, Thomas GJ, Sayan AE, Mirnezami AH.

Methods Mol Biol. 2018;1765:87-98. doi: 10.1007/978-1-4939-7765-9_6.

15.

Acute vascular response to cediranib treatment in human non-small-cell lung cancer xenografts with different tumour stromal architecture.

Jiang Y, Allen D, Kersemans V, Devery AM, Bokobza SM, Smart S, Ryan AJ.

Lung Cancer. 2015 Nov;90(2):191-8. doi: 10.1016/j.lungcan.2015.08.009. Epub 2015 Aug 20.

16.

Patient-derived xenograft models for pancreatic adenocarcinoma demonstrate retention of tumor morphology through incorporation of murine stromal elements.

Delitto D, Pham K, Vlada AC, Sarosi GA, Thomas RM, Behrns KE, Liu C, Hughes SJ, Wallet SM, Trevino JG.

Am J Pathol. 2015 May;185(5):1297-303. doi: 10.1016/j.ajpath.2015.01.016. Epub 2015 Mar 12.

17.

Quantitation of Murine Stroma and Selective Purification of the Human Tumor Component of Patient-Derived Xenografts for Genomic Analysis.

Schneeberger VE, Allaj V, Gardner EE, Poirier JT, Rudin CM.

PLoS One. 2016 Sep 9;11(9):e0160587. doi: 10.1371/journal.pone.0160587. eCollection 2016.

18.

Assessment of the in vivo antitumor effects of ENMD-2076, a novel multitargeted kinase inhibitor, against primary and cell line-derived human colorectal cancer xenograft models.

Tentler JJ, Bradshaw-Pierce EL, Serkova NJ, Hasebroock KM, Pitts TM, Diamond JR, Fletcher GC, Bray MR, Eckhardt SG.

Clin Cancer Res. 2010 Jun 1;16(11):2989-2998. doi: 10.1158/1078-0432.CCR-10-0325. Epub 2010 Apr 20.

19.

A 3D in vitro model of patient-derived prostate cancer xenograft for controlled interrogation of in vivo tumor-stromal interactions.

Fong EL, Wan X, Yang J, Morgado M, Mikos AG, Harrington DA, Navone NM, Farach-Carson MC.

Biomaterials. 2016 Jan;77:164-72. doi: 10.1016/j.biomaterials.2015.10.059. Epub 2015 Nov 9.

20.

Antitumor activity of a potent MEK inhibitor, TAK-733, against colorectal cancer cell lines and patient derived xenografts.

Lieu CH, Klauck PJ, Henthorn PK, Tentler JJ, Tan AC, Spreafico A, Selby HM, Britt BC, Bagby SM, Arcaroli JJ, Messersmith WA, Pitts TM, Eckhardt SG.

Oncotarget. 2015 Oct 27;6(33):34561-72. doi: 10.18632/oncotarget.5949.

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