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Items: 1 to 20 of 103

1.

An L-threonine transaldolase is required for L-threo-β-hydroxy-α-amino acid assembly during obafluorin biosynthesis.

Scott TA, Heine D, Qin Z, Wilkinson B.

Nat Commun. 2017 Jun 26;8:15935. doi: 10.1038/ncomms15935.

2.

β-Lactone formation during product release from a nonribosomal peptide synthetase.

Schaffer JE, Reck MR, Prasad NK, Wencewicz TA.

Nat Chem Biol. 2017 Jul;13(7):737-744. doi: 10.1038/nchembio.2374. Epub 2017 May 15.

PMID:
28504677
3.

Amalgamation of nucleosides and amino acids in antibiotic biosynthesis: discovery of an L-threonine:uridine-5'-aldehyde transaldolase.

Barnard-Britson S, Chi X, Nonaka K, Spork AP, Tibrewal N, Goswami A, Pahari P, Ducho C, Rohr J, Van Lanen SG.

J Am Chem Soc. 2012 Nov 14;134(45):18514-7. doi: 10.1021/ja308185q. Epub 2012 Nov 2.

4.

The Biosynthesis of Capuramycin-type Antibiotics: IDENTIFICATION OF THE A-102395 BIOSYNTHETIC GENE CLUSTER, MECHANISM OF SELF-RESISTANCE, AND FORMATION OF URIDINE-5'-CARBOXAMIDE.

Cai W, Goswami A, Yang Z, Liu X, Green KD, Barnard-Britson S, Baba S, Funabashi M, Nonaka K, Sunkara M, Morris AJ, Spork AP, Ducho C, Garneau-Tsodikova S, Thorson JS, Van Lanen SG.

J Biol Chem. 2015 May 29;290(22):13710-24. doi: 10.1074/jbc.M115.646414. Epub 2015 Apr 8.

5.

Massetolide A biosynthesis in Pseudomonas fluorescens.

de Bruijn I, de Kock MJ, de Waard P, van Beek TA, Raaijmakers JM.

J Bacteriol. 2008 Apr;190(8):2777-89. Epub 2007 Nov 9.

6.

Threonine aldolases-screening, properties and applications in the synthesis of non-proteinogenic beta-hydroxy-alpha-amino acids.

Dückers N, Baer K, Simon S, Gröger H, Hummel W.

Appl Microbiol Biotechnol. 2010 Sep;88(2):409-24. doi: 10.1007/s00253-010-2751-8. Epub 2010 Aug 4. Review.

PMID:
20683718
7.

Molecular characterization of the safracin biosynthetic pathway from Pseudomonas fluorescens A2-2: designing new cytotoxic compounds.

Velasco A, Acebo P, Gomez A, Schleissner C, Rodríguez P, Aparicio T, Conde S, Muñoz R, de la Calle F, Garcia JL, Sánchez-Puelles JM.

Mol Microbiol. 2005 Apr;56(1):144-54.

8.

Insights into an unusual nonribosomal peptide synthetase biosynthesis: identification and characterization of the GE81112 biosynthetic gene cluster.

Binz TM, Maffioli SI, Sosio M, Donadio S, Müller R.

J Biol Chem. 2010 Oct 22;285(43):32710-9. doi: 10.1074/jbc.M110.146803. Epub 2010 Aug 14.

9.

β-Lactone Synthetase Found in the Olefin Biosynthesis Pathway.

Christenson JK, Richman JE, Jensen MR, Neufeld JY, Wilmot CM, Wackett LP.

Biochemistry. 2017 Jan 17;56(2):348-351. doi: 10.1021/acs.biochem.6b01199. Epub 2017 Jan 3.

10.
12.

Insights into fluorometabolite biosynthesis in Streptomyces cattleya DSM46488 through genome sequence and knockout mutants.

Zhao C, Li P, Deng Z, Ou HY, McGlinchey RP, O'Hagan D.

Bioorg Chem. 2012 Oct;44:1-7. doi: 10.1016/j.bioorg.2012.06.002. Epub 2012 Jul 16.

PMID:
22858315
13.

Biosynthesis of the myxobacterial antibiotic corallopyronin A.

Erol O, Schäberle TF, Schmitz A, Rachid S, Gurgui C, El Omari M, Lohr F, Kehraus S, Piel J, Müller R, König GM.

Chembiochem. 2010 Jun 14;11(9):1253-65. doi: 10.1002/cbic.201000085.

PMID:
20503218
14.

Mupirocin: biosynthesis, special features and applications of an antibiotic from a gram-negative bacterium.

Gurney R, Thomas CM.

Appl Microbiol Biotechnol. 2011 Apr;90(1):11-21. doi: 10.1007/s00253-011-3128-3. Epub 2011 Feb 20. Review.

PMID:
21336932
15.

Genome-based discovery, structure prediction and functional analysis of cyclic lipopeptide antibiotics in Pseudomonas species.

de Bruijn I, de Kock MJ, Yang M, de Waard P, van Beek TA, Raaijmakers JM.

Mol Microbiol. 2007 Jan;63(2):417-28.

16.

Synthesis of α-amino acids based on chiral tricycloiminolactone derived from natural (+)-camphor.

Luo YC, Zhang HH, Wang Y, Xu PF.

Acc Chem Res. 2010 Oct 19;43(10):1317-30. doi: 10.1021/ar100050p.

PMID:
20672798
17.

Mupirocin W, a novel pseudomonic acid produced by targeted mutation of the mupirocin biosynthetic gene cluster.

Cooper SM, Cox RJ, Crosby J, Crump MP, Hothersall J, Laosripaiboon W, Simpson TJ, Thomas CM.

Chem Commun (Camb). 2005 Mar 7;(9):1179-81. Epub 2005 Jan 17.

PMID:
15726184
18.

Two novel antibiotics, Sch 419558 and Sch 419559, produced by Pseudomonas fluorescens: effect on activity by overexpression of RpoE.

Yang SW, Xu L, Mierzwa R, He L, Terracciano J, Patel M, Gullo V, Black T, Zhao W, Chan TM, Chu M.

Bioorg Med Chem. 2004 Jun 15;12(12):3333-8.

PMID:
15158801
19.

The structural basis of N-acyl-α-amino-β-lactone formation catalyzed by a nonribosomal peptide synthetase.

Kreitler DF, Gemmell EM, Schaffer JE, Wencewicz TA, Gulick AM.

Nat Commun. 2019 Jul 31;10(1):3432. doi: 10.1038/s41467-019-11383-7.

20.

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