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28646272,21888961,25790951,21195755,35156857,24114773,21875659,27631825,19494572,22699989,17727085,24114866,27556522,9081275,25350405,22326291,26970474,9581394,20184947,15051138,28614181,3879375,26163094,16957501,16562682,29499347,23483451,27050773,29940617,31165284,12701739,12972945,27260269,3258362,15650301,26954875,28068659,17211286,22387110,31916371,24671484,21150687,20513043,15515568,12972912,17453474,15064610,16825889,8588662,11683905,26438271,16012043,29889788,16936569,15891647,14603071,3258363,21575409,17913422,23200870,12121741,11359119,23044932,10771195,15758055,22830312,23413036,24499975,25557394,17869440,8747205,26795351,16170084,14564095,34214947,24622013,21756683,25891801,32818431,25113508,30995152,17260728,24291333,28367981,28362376,25894725,28479241,31980281,27966334,21251965,18300702,19852307,33454767,31422454,31606991,10190751,24938696,28082074,1917713,35292639,11131371,11425207,8260149,28165476,24864261,33243375,10577769,26831119,10102420,29315185,20060033,26796230,20559478,36503867,10748335,29310507,16015182,32602462,29130354,14512836,21298075,22863861,29169906,33784680,30211105,35883470,32244147,22303988,11349769,10384853,30683875,33522002,35991545,23044664,2282220,28802357,25032973,34785080,32380226,19414487,34385909,9822911,30009175,2348283,31353070,12782355,29689410,15841993,22283653,27392187,1707789,10821541,29445157,34298130,25996080,11346428,33514733,23265411,28165475,15937572,15952048,19494573,32849181,18210004,24021919,12211350,23663536,18697796,23528307,32204962,34552193,30670701,30632683,15353999,8747745,18797291,16160526,28438970,30368398,12797577,21988729,35250483,3806443,25867531,32564460,30065296,11248947,31577516,32901490,30690105,22514095,1512654,32503640,35740941,31486693,10733183,30987439,12544029,8643302,29933075,36402256,17011831,15078074,10529904,19848235,36969846,29792920,14977071,37026782,36649664,31128597,25347140,32991625,31736710,26420843,36891922,36278489,31866822,30762456,20628639,12359252,9840510,30274337,22991972,8283344,31489779,26634063,31278973,29074310,15500409,30706399,32403103,36460053,35295154,29759021,21338273,36203796,32145977,25382757,10372067,32323262,30206231,32247629,8749133,7607817,32956992,31293415,34489646,34174443,37108158,33897611,35685768,16158531,23560526,2282211,23136997,32419976,25467523,3680059,30442227,29392065,31244619,29553522,32442531,14558725,21472006,24015503,32681585,24265785,32884557,11792532,28254438,32173115,485945,18099625,36965335,35609593,32714382,23649285,29937836,28815315,10820324,30805407,30870369,33492056,34768526,33041966,32708116,24804196,36293251,29301391,29551306,29889202,15078077,13443921,28245737,19923805,9872139,36179346,2648747,32426022,20149854,12204354,18453751,29553564,18110567,31994336,22912830,16470473,1524811,2750462,32514364,29519617,35821484,32068262,33484073,32796705,35026456,33850952,13382283,35346415,30105484,31810596,33246067,9105475,32725028,12121749,34566562,34733133,27547558,31293387,16600193,15803007,28853245,22991942,34776942,34970112,3218493,17330152,31789795,37008271,30972560,31455802,32484378,34342719,32775487,33604229,20714881,20969946,814887,30564989,7915484,11335015,11425205,23575422,20057387,12438847,9616696,11123168,22484222,24108151,31632328,7608399,36839763,32525749,32246510,8459653,34072013,18288464,36351232,29038666,34774232,24549508,28549377,29937785,15853667,2195634,34537343,32304785,35193350,34198685,29318324,32603645,34497573,20402646,29450596,19617827,30859735,32596497,29796015,30117612,28684743,32363942,35820254,29933376,31602092,20046821,30532693,30599032,32823037,31949839,32116980,30842313,31372322,8928635,32047431,35811200,30113566,24956306,36598271,22206578,26738500,26029729,18231694,35434314,11766689,34619343,25299831,22207864,35273964,34761700,8749194,35444606,32310224,30666848,36347918,3228184,36188374,21866215,36090148,37031766,35087833,20235454,34054423,18210008,34335453,30108474,6591689,30891447,22267939,30644374,36189895,24427559,1927465,28393118,22624825,34526880,28824370,33841317,32953927,22386561,35659555,29937797,29937838,25674062,31213478,35693004,24391537,10028414,21519551,24645675,22841304,34539328,36769694,18106950,29872380,30422573,30045104,34477535,22567353,36609852,10452381,28229056,33344461,36331565,35223817,10207957,28264554,32796268,21665849,30397431,31244750,579985,30814937,36212020,14839019,35863163,37143895,23793222,34589045,22593203,24160754,36538754,34059922,25254216,30635991,32635986,14664770,31827535,34460675,22720014,19494575,37036024,35813023,30671091,31193276,1952602,35239617,31227837,31916408,27579336,37123250,26527944,35505776,29471610,24324413,36556073,29104815,32092560,35683076,36945521,30210291,21966254,36247525,36731442,28573026,33733250,33383894,34069537,34924960,31244616,34692703,3341152,15623551,19119529,34331740,30285400,34199855,3499018,17119774,25251246,29193857,32822819,20283039,36268215,18111520,31198620,31379508,32624335,31827988,29962850,25346568,37060559,20239947,29916059,34067544,14873822,22073049,18105386,23119287,13933779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Rhesus Cochlear and Vestibular Functions Are Preserved After Inner Ear Injection of Saline Volume Sufficient for Gene Therapy Delivery.

Dai C, Lehar M, Sun DQ, Rvt LS, Carey JP, MacLachlan T, Brough D, Staecker H, Della Santina AM, Hullar TE, Della Santina CC. Dai C, et al. J Assoc Res Otolaryngol. 2017 Aug;18(4):601-617. doi: 10.1007/s10162-017-0628-6. Epub 2017 Jun 23. J Assoc Res Otolaryngol. 2017. PMID: 28646272 Free PMC article.

Restoration of 3D vestibular sensation in rhesus monkeys using a multichannel vestibular prosthesis.

Dai C, Fridman GY, Davidovics NS, Chiang B, Ahn JH, Della Santina CC. Dai C, et al. Hear Res. 2011 Nov;281(1-2):74-83. doi: 10.1016/j.heares.2011.08.008. Epub 2011 Aug 26. Hear Res. 2011. PMID: 21888961 Free PMC article.

Histopathologic Changes of the Inner ear in Rhesus Monkeys After Intratympanic Gentamicin Injection and Vestibular Prosthesis Electrode Array Implantation.

Sun DQ, Lehar M, Dai C, Swarthout L, Lauer AM, Carey JP, Mitchell DE, Cullen KE, Della Santina CC. Sun DQ, et al. J Assoc Res Otolaryngol. 2015 Jun;16(3):373-87. doi: 10.1007/s10162-015-0515-y. Epub 2015 Mar 20. J Assoc Res Otolaryngol. 2015. PMID: 25790951 Free PMC article.

Effects of vestibular prosthesis electrode implantation and stimulation on hearing in rhesus monkeys.

Dai C, Fridman GY, Della Santina CC. Dai C, et al. Hear Res. 2011 Jul;277(1-2):204-10. doi: 10.1016/j.heares.2010.12.021. Epub 2010 Dec 31. Hear Res. 2011. PMID: 21195755 Free PMC article.

Efficient Delivery of Adeno-Associated Virus into Inner Ear In Vivo Through Trans-Stapes Route in Adult Guinea Pig.

Wang J, Zhao L, Gu X, Xue Y, Wang S, Xiao R, Vandenberghe LH, Peng KA, Shu Y, Li H. Wang J, et al. Hum Gene Ther. 2022 Jul;33(13-14):719-728. doi: 10.1089/hum.2021.236. Epub 2022 May 19. Hum Gene Ther. 2022. PMID: 35156857

Down syndrome: an electrophysiological and radiological profile.

Saliba I, Sbeity S, El-Zir E, Yammine FG, Noun CT, Haddad A. Saliba I, et al. Laryngoscope. 2014 Apr;124(4):E141-7. doi: 10.1002/lary.24375. Epub 2013 Dec 17. Laryngoscope. 2014. PMID: 24114773

Mature middle and inner ears express Chd7 and exhibit distinctive pathologies in a mouse model of CHARGE syndrome.

Hurd EA, Adams ME, Layman WS, Swiderski DL, Beyer LA, Halsey KE, Benson JM, Gong TW, Dolan DF, Raphael Y, Martin DM. Hurd EA, et al. Hear Res. 2011 Dec;282(1-2):184-95. doi: 10.1016/j.heares.2011.08.005. Epub 2011 Aug 23. Hear Res. 2011. PMID: 21875659 Free PMC article.

Applying Neurotrophins to the Round Window Rescues Auditory Function and Reduces Inner Hair Cell Synaptopathy After Noise-induced Hearing Loss.

Sly DJ, Campbell L, Uschakov A, Saief ST, Lam M, O'Leary SJ. Sly DJ, et al. Otol Neurotol. 2016 Oct;37(9):1223-30. doi: 10.1097/MAO.0000000000001191. Otol Neurotol. 2016. PMID: 27631825

Repair of the vestibular system via adenovector delivery of Atoh1: a potential treatment for balance disorders.

Baker K, Brough DE, Staecker H. Baker K, et al. Adv Otorhinolaryngol. 2009;66:52-63. doi: 10.1159/000218207. Epub 2009 Jun 2. Adv Otorhinolaryngol. 2009. PMID: 19494572 Review.

Implantation of the semicircular canals with preservation of hearing and rotational sensitivity: a vestibular neurostimulator suitable for clinical research.

Rubinstein JT, Bierer S, Kaneko C, Ling L, Nie K, Oxford T, Newlands S, Santos F, Risi F, Abbas PJ, Phillips JO. Rubinstein JT, et al. Otol Neurotol. 2012 Jul;33(5):789-96. doi: 10.1097/MAO.0b013e318254ec24. Otol Neurotol. 2012. PMID: 22699989 Free PMC article.

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