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Items: 1 to 20 of 97

1.

Structural insight for the recognition of G-quadruplex structure at human c-myc promoter sequence by flavonoid Quercetin.

Tawani A, Mishra SK, Kumar A.

Sci Rep. 2017 Jun 15;7(1):3600. doi: 10.1038/s41598-017-03906-3.

2.

Structural Insight into the interaction of Flavonoids with Human Telomeric Sequence.

Tawani A, Kumar A.

Sci Rep. 2015 Dec 2;5:17574. doi: 10.1038/srep17574.

3.
4.

Stabilization of G-quadruplex DNA with platinum(II) Schiff base complexes: luminescent probe and down-regulation of c-myc oncogene expression.

Wu P, Ma DL, Leung CH, Yan SC, Zhu N, Abagyan R, Che CM.

Chemistry. 2009 Dec 7;15(47):13008-21. doi: 10.1002/chem.200901943.

PMID:
19876976
5.

Structure-based design of platinum(II) complexes as c-myc oncogene down-regulators and luminescent probes for G-quadruplex DNA.

Wang P, Leung CH, Ma DL, Yan SC, Che CM.

Chemistry. 2010 Jun 18;16(23):6900-11. doi: 10.1002/chem.201000167.

PMID:
20437426
6.

Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter.

Phan AT, Kuryavyi V, Gaw HY, Patel DJ.

Nat Chem Biol. 2005 Aug;1(3):167-73. Epub 2005 Jul 17. Erratum in: Nat Chem Biol. 2005 Sep;1(4):234.

7.

A dihydroindolizino indole derivative selectively stabilizes G-quadruplex DNA and down-regulates c-MYC expression in human cancer cells.

Nagesh N, Raju G, Srinivas R, Ramesh P, Reddy MD, Reddy ChR.

Biochim Biophys Acta. 2015 Jan;1850(1):129-40. doi: 10.1016/j.bbagen.2014.10.004. Epub 2014 Oct 15.

PMID:
25452213
8.

Novel interaction of the Z-DNA binding domain of human ADAR1 with the oncogenic c-Myc promoter G-quadruplex.

Kang HJ, Le TV, Kim K, Hur J, Kim KK, Park HJ.

J Mol Biol. 2014 Jul 15;426(14):2594-604. doi: 10.1016/j.jmb.2014.05.001. Epub 2014 May 9.

PMID:
24813121
9.

Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription.

Siddiqui-Jain A, Grand CL, Bearss DJ, Hurley LH.

Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11593-8. Epub 2002 Aug 23.

10.

Structure-based optimization of FDA-approved drug methylene blue as a c-myc G-quadruplex DNA stabilizer.

Chan DS, Yang H, Kwan MH, Cheng Z, Lee P, Bai LP, Jiang ZH, Wong CY, Fong WF, Leung CH, Ma DL.

Biochimie. 2011 Jun;93(6):1055-64. doi: 10.1016/j.biochi.2011.02.013. Epub 2011 Mar 4.

PMID:
21377506
11.

Cell penetrating thiazole peptides inhibit c-MYC expression via site-specific targeting of c-MYC G-quadruplex.

Dutta D, Debnath M, Müller D, Paul R, Das T, Bessi I, Schwalbe H, Dash J.

Nucleic Acids Res. 2018 Jun 20;46(11):5355-5365. doi: 10.1093/nar/gky385.

12.

An intramolecular G-quadruplex structure with mixed parallel/antiparallel G-strands formed in the human BCL-2 promoter region in solution.

Dai J, Dexheimer TS, Chen D, Carver M, Ambrus A, Jones RA, Yang D.

J Am Chem Soc. 2006 Feb 1;128(4):1096-8.

13.

Nemorubicin and doxorubicin bind the G-quadruplex sequences of the human telomeres and of the c-MYC promoter element Pu22.

Scaglioni L, Mondelli R, Artali R, Sirtori FR, Mazzini S.

Biochim Biophys Acta. 2016 Jun;1860(6):1129-38. doi: 10.1016/j.bbagen.2016.02.011. Epub 2016 Feb 23.

PMID:
26922833
14.

Structure-based design of flavone derivatives as c-myc oncogene down-regulators.

Yang H, Zhong HJ, Leung KH, Chan DS, Ma VP, Fu WC, Nanjunda R, Wilson WD, Ma DL, Leung CH.

Eur J Pharm Sci. 2013 Jan 23;48(1-2):130-41. doi: 10.1016/j.ejps.2012.10.010. Epub 2012 Nov 2.

PMID:
23127826
15.

Discovery of a New Four-Leaf Clover-Like Ligand as a Potent c-MYC Transcription Inhibitor Specifically Targeting the Promoter G-Quadruplex.

Hu MH, Wang YQ, Yu ZY, Hu LN, Ou TM, Chen SB, Huang ZS, Tan JH.

J Med Chem. 2018 Mar 22;61(6):2447-2459. doi: 10.1021/acs.jmedchem.7b01697. Epub 2018 Mar 1.

PMID:
29474069
16.

Solution structure of a G-quadruplex bound to the bisquinolinium compound Phen-DC(3).

Chung WJ, Heddi B, Hamon F, Teulade-Fichou MP, Phan AT.

Angew Chem Int Ed Engl. 2014 Jan 20;53(4):999-1002. doi: 10.1002/anie.201308063. Epub 2013 Dec 16.

PMID:
24356977
17.

Structure of the biologically relevant G-quadruplex in the c-MYC promoter.

Yang D, Hurley LH.

Nucleosides Nucleotides Nucleic Acids. 2006;25(8):951-68. Review.

PMID:
16901825
18.

Carbazole ligands as c-myc G-quadruplex binders.

Głuszyńska A, Juskowiak B, Kuta-Siejkowska M, Hoffmann M, Haider S.

Int J Biol Macromol. 2018 Jul 15;114:479-490. doi: 10.1016/j.ijbiomac.2018.03.135. Epub 2018 Mar 23.

PMID:
29581003
19.

Not all G-quadruplexes are created equally: an investigation of the structural polymorphism of the c-Myc G-quadruplex-forming sequence and its interaction with the porphyrin TMPyP4.

Le HT, Miller MC, Buscaglia R, Dean WL, Holt PA, Chaires JB, Trent JO.

Org Biomol Chem. 2012 Dec 21;10(47):9393-404. doi: 10.1039/c2ob26504d. Epub 2012 Oct 29.

20.

Effect of Ionic Strength on Porphyrin Drugs Interaction with Quadruplex DNA Formed by the Promoter Region of C-myc and Bcl2 Oncogenes.

Nagesh N, Sharma VK, Ganesh Kumar A, Lewis EA.

J Nucleic Acids. 2010;2010. pii: 146418. doi: 10.4061/2010/146418. Epub 2009 Oct 18.

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