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Items: 1 to 20 of 152

1.

Quantitative and qualitative iNKT repertoire associations with disease susceptibility and outcome in macaque tuberculosis infection.

Chancellor A, White A, Tocheva AS, Fenn JR, Dennis M, Tezera L, Singhania A, Elliott T, Tebruegge M, Elkington P, Gadola S, Sharpe S, Mansour S.

Tuberculosis (Edinb). 2017 Jul;105:86-95. doi: 10.1016/j.tube.2017.04.011. Epub 2017 Apr 28.

2.

Innate invariant NKT cells recognize Mycobacterium tuberculosis-infected macrophages, produce interferon-gamma, and kill intracellular bacteria.

Sada-Ovalle I, Chiba A, Gonzales A, Brenner MB, Behar SM.

PLoS Pathog. 2008 Dec;4(12):e1000239. doi: 10.1371/journal.ppat.1000239. Epub 2008 Dec 12.

3.

The TB-specific CD4(+) T cell immune repertoire in both cynomolgus and rhesus macaques largely overlap with humans.

Mothé BR, Lindestam Arlehamn CS, Dow C, Dillon MBC, Wiseman RW, Bohn P, Karl J, Golden NA, Gilpin T, Foreman TW, Rodgers MA, Mehra S, Scriba TJ, Flynn JL, Kaushal D, O'Connor DH, Sette A.

Tuberculosis (Edinb). 2015 Dec;95(6):722-735. doi: 10.1016/j.tube.2015.07.005. Epub 2015 Aug 28.

4.

Aerosol vaccination with AERAS-402 elicits robust cellular immune responses in the lungs of rhesus macaques but fails to protect against high-dose Mycobacterium tuberculosis challenge.

Darrah PA, Bolton DL, Lackner AA, Kaushal D, Aye PP, Mehra S, Blanchard JL, Didier PJ, Roy CJ, Rao SS, Hokey DA, Scanga CA, Sizemore DR, Sadoff JC, Roederer M, Seder RA.

J Immunol. 2014 Aug 15;193(4):1799-811. doi: 10.4049/jimmunol.1400676. Epub 2014 Jul 14.

5.

Prime-boost vaccination strategy with bacillus Calmette-Guérin (BCG) and liposomized alpha-crystalline protein 1 reinvigorates BCG potency.

Siddiqui KF, Amir M, Khan N, Rama Krishna G, Sheikh JA, Rajagopal K, Agrewala JN.

Clin Exp Immunol. 2015 Aug;181(2):286-96. doi: 10.1111/cei.12634. Epub 2015 Jun 3.

6.

Sendai Virus Mucosal Vaccination Establishes Lung-Resident Memory CD8 T Cell Immunity and Boosts BCG-Primed Protection against TB in Mice.

Hu Z, Wong KW, Zhao HM, Wen HL, Ji P, Ma H, Wu K, Lu SH, Li F, Li ZM, Shu T, Xu JQ, Lowrie DB, Fan XY.

Mol Ther. 2017 May 3;25(5):1222-1233. doi: 10.1016/j.ymthe.2017.02.018. Epub 2017 Mar 23.

7.

Alternative BCG delivery strategies improve protection against Mycobacterium tuberculosis in non-human primates: Protection associated with mycobacterial antigen-specific CD4 effector memory T-cell populations.

Sharpe S, White A, Sarfas C, Sibley L, Gleeson F, McIntyre A, Basaraba R, Clark S, Hall G, Rayner E, Williams A, Marsh PD, Dennis M.

Tuberculosis (Edinb). 2016 Dec;101:174-190. doi: 10.1016/j.tube.2016.09.004. Epub 2016 Oct 8.

8.

TCR repertoire, clonal dominance, and pulmonary trafficking of mycobacterium-specific CD4+ and CD8+ T effector cells in immunity against tuberculosis.

Du G, Chen CY, Shen Y, Qiu L, Huang D, Wang R, Chen ZW.

J Immunol. 2010 Oct 1;185(7):3940-7. doi: 10.4049/jimmunol.1001222. Epub 2010 Aug 30.

9.

Loss of effector and anti-inflammatory natural killer T lymphocyte function in pathogenic simian immunodeficiency virus infection.

Rout N, Greene J, Yue S, O'Connor D, Johnson RP, Else JG, Exley MA, Kaur A.

PLoS Pathog. 2012 Sep;8(9):e1002928. doi: 10.1371/journal.ppat.1002928. Epub 2012 Sep 20.

10.

Humanized NOG mice as a model for tuberculosis vaccine-induced immunity: a comparative analysis with the mouse and guinea pig models of tuberculosis.

Grover A, Troy A, Rowe J, Troudt JM, Creissen E, McLean J, Banerjee P, Feuer G, Izzo AA.

Immunology. 2017 Sep;152(1):150-162. doi: 10.1111/imm.12756. Epub 2017 Jun 19.

11.

Repeated Aerosolized-Boosting with Gamma-Irradiated Mycobacterium bovis BCG Confers Improved Pulmonary Protection against the Hypervirulent Mycobacterium tuberculosis Strain HN878 in Mice.

Cha SB, Kim WS, Kim JS, Kim H, Kwon KW, Han SJ, Eum SY, Cho SN, Shin SJ.

PLoS One. 2015 Oct 28;10(10):e0141577. doi: 10.1371/journal.pone.0141577. eCollection 2015.

12.

Diversity of Human and Macaque Airway Immune Cells at Baseline and during Tuberculosis Infection.

Silver RF, Myers AJ, Jarvela J, Flynn J, Rutledge T, Bonfield T, Lin PL.

Am J Respir Cell Mol Biol. 2016 Dec;55(6):899-908.

13.

ESAT-6-dependent cytosolic pattern recognition drives noncognate tuberculosis control in vivo.

Kupz A, Zedler U, Stäber M, Perdomo C, Dorhoi A, Brosch R, Kaufmann SH.

J Clin Invest. 2016 Jun 1;126(6):2109-22. doi: 10.1172/JCI84978. Epub 2016 Apr 25.

14.

Using Data from Macaques To Predict Gamma Interferon Responses after Mycobacterium bovis BCG Vaccination in Humans: a Proof-of-Concept Study of Immunostimulation/Immunodynamic Modeling Methods.

Rhodes SJ, Sarfas C, Knight GM, White A, Pathan AA, McShane H, Evans TG, Fletcher H, Sharpe S, White RG.

Clin Vaccine Immunol. 2017 Mar 6;24(3). pii: e00525-16. doi: 10.1128/CVI.00525-16. Print 2017 Mar.

15.

BCG constitutively expressing the adenylyl cyclase encoded by Rv2212 increases its immunogenicity and reduces replication of M. tuberculosis in lungs of BALB/c mice.

Pedroza-Roldán C, Marquina-Castillo B, Mata-Espinosa D, Barrios-Payán J, Aceves-Sánchez MJ, Hernández Pando R, Flores-Valdez MA.

Tuberculosis (Edinb). 2018 Dec;113:19-25. doi: 10.1016/j.tube.2018.08.012. Epub 2018 Aug 24.

PMID:
30514503
16.

Evaluation of the Immunogenicity of Mycobacterium bovis BCG Delivered by Aerosol to the Lungs of Macaques.

White AD, Sarfas C, West K, Sibley LS, Wareham AS, Clark S, Dennis MJ, Williams A, Marsh PD, Sharpe SA.

Clin Vaccine Immunol. 2015 Sep;22(9):992-1003. doi: 10.1128/CVI.00289-15. Epub 2015 Jun 24.

17.

Incorporation of NKT cell-activating glycolipids enhances immunogenicity and vaccine efficacy of Mycobacterium bovis bacillus Calmette-Guerin.

Venkataswamy MM, Baena A, Goldberg MF, Bricard G, Im JS, Chan J, Reddington F, Besra GS, Jacobs WR Jr, Porcelli SA.

J Immunol. 2009 Aug 1;183(3):1644-56. doi: 10.4049/jimmunol.0900858.

18.

Attrition of T-cell functions and simultaneous upregulation of inhibitory markers correspond with the waning of BCG-induced protection against tuberculosis in mice.

Nandakumar S, Kannanganat S, Posey JE, Amara RR, Sable SB.

PLoS One. 2014 Nov 24;9(11):e113951. doi: 10.1371/journal.pone.0113951. eCollection 2014.

19.

Genome wide approaches discover novel Mycobacterium tuberculosis antigens as correlates of infection, disease, immunity and targets for vaccination.

Coppola M, Ottenhoff TH.

Semin Immunol. 2018 Oct;39:88-101. doi: 10.1016/j.smim.2018.07.001. Epub 2018 Jul 7. Review.

20.

Alpha-galactosylceramide as a therapeutic agent for pulmonary Mycobacterium tuberculosis infection.

Sada-Ovalle I, Sköld M, Tian T, Besra GS, Behar SM.

Am J Respir Crit Care Med. 2010 Sep 15;182(6):841-7. doi: 10.1164/rccm.200912-1921OC. Epub 2010 May 27.

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