Similar articles for PMID: 28601510

Year	Number of Results
1984	1
1989	1
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2000	1
2003	2
2004	2
2005	1
2006	6
2007	2
2008	2
2009	4
2010	3
2011	7
2012	6
2013	8
2014	2
2015	12
2016	3
2017	6
2018	4
2019	5
2020	2
2021	1
2022	5
2024	0

1

Synthesis and evaluation of symmetric acyclic nucleoside bisphosphonates as inhibitors of the Plasmodium falciparum, Plasmodium vivax and human 6-oxopurine phosphoribosyltransferases and the antimalarial activity of their prodrugs.

Špaček P, Keough DT, Chavchich M, Dračínský M, Janeba Z, Naesens L, Edstein MD, Guddat LW, Hocková D. Špaček P, et al. Bioorg Med Chem. 2017 Aug 1;25(15):4008-4030. doi: 10.1016/j.bmc.2017.05.048. Epub 2017 May 24. Bioorg Med Chem. 2017. PMID: 28601510

2

Aza-acyclic nucleoside phosphonates containing a second phosphonate group as inhibitors of the human, Plasmodium falciparum and vivax 6-oxopurine phosphoribosyltransferases and their prodrugs as antimalarial agents.

Keough DT, Hocková D, Janeba Z, Wang TH, Naesens L, Edstein MD, Chavchich M, Guddat LW. Keough DT, et al. J Med Chem. 2015 Jan 22;58(2):827-46. doi: 10.1021/jm501416t. Epub 2014 Dec 24. J Med Chem. 2015. PMID: 25494538

3

Sulfide, sulfoxide and sulfone bridged acyclic nucleoside phosphonates as inhibitors of the Plasmodium falciparum and human 6-oxopurine phosphoribosyltransferases: Synthesis and evaluation.

Klejch T, Keough DT, Chavchich M, Travis J, Skácel J, Pohl R, Janeba Z, Edstein MD, Avery VM, Guddat LW, Hocková D. Klejch T, et al. Eur J Med Chem. 2019 Dec 1;183:111667. doi: 10.1016/j.ejmech.2019.111667. Epub 2019 Sep 4. Eur J Med Chem. 2019. PMID: 31536893

4

Nucleotide analogues containing a pyrrolidine, piperidine or piperazine ring: Synthesis and evaluation of inhibition of plasmodial and human 6-oxopurine phosphoribosyltransferases and in vitro antimalarial activity.

Frydrych J, Keough DT, Chavchich M, Travis J, Dračínský M, Edstein MD, Guddat LW, Hocková D, Janeba Z. Frydrych J, et al. Eur J Med Chem. 2021 Jul 5;219:113416. doi: 10.1016/j.ejmech.2021.113416. Epub 2021 Apr 3. Eur J Med Chem. 2021. PMID: 33887682

5

Synthesis of novel N-branched acyclic nucleoside phosphonates as potent and selective inhibitors of human, Plasmodium falciparum and Plasmodium vivax 6-oxopurine phosphoribosyltransferases.

Hocková D, Keough DT, Janeba Z, Wang TH, de Jersey J, Guddat LW. Hocková D, et al. J Med Chem. 2012 Jul 12;55(13):6209-23. doi: 10.1021/jm300662d. Epub 2012 Jun 22. J Med Chem. 2012. PMID: 22725979

6

Synthesis and Evaluation of Asymmetric Acyclic Nucleoside Bisphosphonates as Inhibitors of Plasmodium falciparum and Human Hypoxanthine-Guanine-(Xanthine) Phosphoribosyltransferase.

Špaček P, Keough DT, Chavchich M, Dračínský M, Janeba Z, Naesens L, Edstein MD, Guddat LW, Hocková D. Špaček P, et al. J Med Chem. 2017 Sep 14;60(17):7539-7554. doi: 10.1021/acs.jmedchem.7b00926. Epub 2017 Aug 30. J Med Chem. 2017. PMID: 28813147

7

Synthesis and Evaluation of Novel Acyclic Nucleoside Phosphonates as Inhibitors of Plasmodium falciparum and Human 6-Oxopurine Phosphoribosyltransferases.

Kaiser MM, Hocková D, Wang TH, Dračínský M, Poštová-Slavětínská L, Procházková E, Edstein MD, Chavchich M, Keough DT, Guddat LW, Janeba Z. Kaiser MM, et al. ChemMedChem. 2015 Oct;10(10):1707-23. doi: 10.1002/cmdc.201500322. Epub 2015 Aug 25. ChemMedChem. 2015. PMID: 26368337

8

Acyclic nucleoside phosphonates containing a second phosphonate group are potent inhibitors of 6-oxopurine phosphoribosyltransferases and have antimalarial activity.

Keough DT, Špaček P, Hocková D, Tichý T, Vrbková S, Slavětínská L, Janeba Z, Naesens L, Edstein MD, Chavchich M, Wang TH, de Jersey J, Guddat LW. Keough DT, et al. J Med Chem. 2013 Mar 28;56(6):2513-26. doi: 10.1021/jm301893b. Epub 2013 Mar 19. J Med Chem. 2013. PMID: 23448281

9

Synthesis of purine N9-[2-hydroxy-3-O-(phosphonomethoxy)propyl] derivatives and their side-chain modified analogs as potential antimalarial agents.

Krečmerová M, Dračínský M, Hocková D, Holý A, Keough DT, Guddat LW. Krečmerová M, et al. Bioorg Med Chem. 2012 Feb 1;20(3):1222-30. doi: 10.1016/j.bmc.2011.12.034. Epub 2011 Dec 30. Bioorg Med Chem. 2012. PMID: 22249123

10

Antimalarial activity of prodrugs of N-branched acyclic nucleoside phosphonate inhibitors of 6-oxopurine phosphoribosyltransferases.

Hocková D, Janeba Z, Naesens L, Edstein MD, Chavchich M, Keough DT, Guddat LW. Hocková D, et al. Bioorg Med Chem. 2015 Sep 1;23(17):5502-10. doi: 10.1016/j.bmc.2015.07.038. Epub 2015 Jul 27. Bioorg Med Chem. 2015. PMID: 26275679

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