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Items: 1 to 20 of 114

1.

Neutralization of Inflammation by Inhibiting In vitro and In vivo Secretory Phospholipase A2 by Ethanol Extract of Boerhaavia diffusa L.

Giresha AS, Pramod SN, Sathisha AD, Dharmappa KK.

Pharmacognosy Res. 2017 Apr-Jun;9(2):174-181. doi: 10.4103/0974-8490.204650.

2.

Group IIA secretory PLA2 inhibition by ursolic acid: a potent anti-inflammatory molecule.

Nataraju A, Raghavendra Gowda CD, Rajesh R, Vishwanath BS.

Curr Top Med Chem. 2007;7(8):801-9.

PMID:
17456043
3.

Anti-inflammatory activity of oleanolic acid by inhibition of secretory phospholipase A2.

Dharmappa KK, Kumar RV, Nataraju A, Mohamed R, Shivaprasad HV, Vishwanath BS.

Planta Med. 2009 Feb;75(3):211-5. doi: 10.1055/s-0028-1088374. Epub 2008 Dec 11.

PMID:
19085684
4.

Inhibition of Group IIA Secretory Phospholipase A2 and its Inflammatory Reactions in Mice by Ethanolic Extract of Andrographis paniculata, a Well-known Medicinal Food.

Kishore V, Yarla NS, Zameer F, Nagendra Prasad MN, Santosh MS, More SS, Rao DG, Dhananjaya BL.

Pharmacognosy Res. 2016 Jul-Sep;8(3):213-6. doi: 10.4103/0974-8490.182916.

5.

Genistein, a potent inhibitor of secretory phospholipase A2: a new insight in down regulation of inflammation.

Dharmappa KK, Mohamed R, Shivaprasad HV, Vishwanath BS.

Inflammopharmacology. 2010 Feb;18(1):25-31. doi: 10.1007/s10787-009-0018-8. Epub 2009 Nov 6.

PMID:
19894024
6.

Chemical modification of ascorbic acid and evaluation of its lipophilic derivatives as inhibitors of secretory phospholipase A(2) with anti-inflammatory activity.

Mohamed R, Dharmappa KK, Tarannum S, Jameel NM, Kannum SA, Ashrafulla HS, Rai L, Souza CJ, Shekhar MA, Vishwanath BS.

Mol Cell Biochem. 2010 Dec;345(1-2):69-76. doi: 10.1007/s11010-010-0561-z. Epub 2010 Aug 22.

PMID:
20730622
7.

Attenuation of Oxidative Damage by Boerhaavia diffusa L. Against Different Neurotoxic Agents in Rat Brain Homogenate.

Ayyappan P, Palayyan SR, Kozhiparambil Gopalan R.

J Diet Suppl. 2016;13(3):300-12. doi: 10.3109/19390211.2015.1036186. Epub 2015 Aug 13.

PMID:
26268727
8.

Neutralization of Naja naja venom induced lethality, edema and myonecrosis by ethanolic root extract of Coix lacryma-jobi.

Rajesh KS, Bharath BR, Rao CV, Bhat KI, Bhat KSC, Bhat P.

Toxicol Rep. 2017 Nov 24;4:637-645. doi: 10.1016/j.toxrep.2017.11.005. eCollection 2017.

9.

Effect of umbelliferone (7-hydroxycoumarin, 7-HOC) on the enzymatic, edematogenic and necrotic activities of secretory phospholipase A2 (sPLA2) isolated from Crotalus durissus collilineatus venom.

Toyama DO, Marangoni S, Diz-Filho EB, Oliveira SC, Toyama MH.

Toxicon. 2009 Mar 15;53(4):417-26. doi: 10.1016/j.toxicon.2008.12.018.

PMID:
19470355
10.

Mouse group X secretory phospholipase A2 induces a potent release of arachidonic acid from spleen cells and acts as a ligand for the phospholipase A2 receptor.

Morioka Y, Saiga A, Yokota Y, Suzuki N, Ikeda M, Ono T, Nakano K, Fujii N, Ishizaki J, Arita H, Hanasaki K.

Arch Biochem Biophys. 2000 Sep 1;381(1):31-42.

PMID:
11019817
11.

Non-Clinical Studies for Evaluation of 8-C-Rhamnosyl Apigenin Purified from Peperomia obtusifolia against Acute Edema.

Tamayose CI, Romoff P, Toyama DO, Gaeta HH, Costa CRC, Belchor MN, Ortolan BD, Velozo LSM, Kaplan MAC, Ferreira MJP, Toyama MH.

Int J Mol Sci. 2017 Sep 14;18(9). pii: E1972. doi: 10.3390/ijms18091972.

12.

Recombinant human secretory phospholipase A2 released thromboxane from guinea pig bronchoalveolar lavage cells: in vitro and ex vivo evaluation of a novel secretory phospholipase A2 inhibitor.

Fleisch JH, Armstrong CT, Roman CR, Mihelich ED, Spaethe SM, Jackson WT, Bobbitt JL, Draheim S, Bach NJ, Dillard RD, Martinelli M, Fouts R, Snyder DW.

J Pharmacol Exp Ther. 1996 Jul;278(1):252-7.

PMID:
8764358
13.

Synthesis, characterization and bioactivity studies of novel 1,3,4-oxadiazole small molecule that targets basic phospholipase A2 from Vipera russelli.

Kameshwar VH, R KJ, Priya BS, Swamy SN.

Mol Cell Biochem. 2017 Feb;426(1-2):161-175. doi: 10.1007/s11010-016-2888-6. Epub 2016 Dec 7.

PMID:
27928710
14.

The standard aqueous stem bark extract of Mangifera indica L. inhibits toxic PLA2 - NN-XIb-PLA2 of Indian cobra venom.

Dhananjaya BL, Sudarshan S, Dongol Y, More SS.

Saudi Pharm J. 2016 May;24(3):371-8. doi: 10.1016/j.jsps.2016.04.026. Epub 2016 Apr 30.

15.

Modulation of acute and chronic inflammatory processes by cacospongionolide B, a novel inhibitor of human synovial phospholipase A2.

García Pastor P, De Rosa S, De Giulio A, Payá M, Alcaraz MJ.

Br J Pharmacol. 1999 Jan;126(1):301-11.

17.

Evaluating the inhibitory potential of Withania somnifera on platelet aggregation and inflammation enzymes: An in vitro and in silico study.

M M, Zameer F, Naidu A, M N NP, Dhananjaya BL, Hegdekatte R.

Pharm Biol. 2016 Sep;54(9):1936-41. doi: 10.3109/13880209.2015.1123729. Epub 2015 Dec 24.

PMID:
26704448
18.

Alpha-lipoic acid: an inhibitor of secretory phospholipase A2 with anti-inflammatory activity.

Jameel NM, Shekhar MA, Vishwanath BS.

Life Sci. 2006 Dec 14;80(2):146-53. Epub 2006 Sep 1.

PMID:
17011589
19.

A novel anti-inflammatory role for secretory phospholipase A2 in immune complex-mediated arthritis.

Boilard E, Lai Y, Larabee K, Balestrieri B, Ghomashchi F, Fujioka D, Gobezie R, Coblyn JS, Weinblatt ME, Massarotti EM, Thornhill TS, Divangahi M, Remold H, Lambeau G, Gelb MH, Arm JP, Lee DM.

EMBO Mol Med. 2010 May;2(5):172-87. doi: 10.1002/emmm.201000072.

20.

Inhibition of Naja naja venom enzymes by the methanolic extract of Leucas aspera and its chemical profile by GC-MS.

Gopi K, Renu K, Jayaraman G.

Toxicol Rep. 2014 Aug 29;1:667-673. doi: 10.1016/j.toxrep.2014.08.012. eCollection 2014.

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