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Items: 1 to 20 of 102

1.

Wntless promotes bladder cancer growth and acts synergistically as a molecular target in combination with cisplatin.

Schmid SC, Sathe A, Guerth F, Seitz AK, Heck MM, Maurer T, Schwarzenböck SM, Krause BJ, Schulz WA, Stoehr R, Gschwend JE, Retz M; German Bladder Cancer Network, Nawroth R.

Urol Oncol. 2017 Sep;35(9):544.e1-544.e10. doi: 10.1016/j.urolonc.2017.04.015. Epub 2017 May 10.

PMID:
28501564
2.

Concentration-dependent effects of WNTLESS on WNT1/3A signaling.

Galli LM, Szabo LA, Li L, Htaik YM, Onguka O, Burrus LW.

Dev Dyn. 2014 Sep;243(9):1095-105. doi: 10.1002/dvdy.24149. Epub 2014 Jun 25.

3.

Mesenchymal Wnt signaling promotes formation of sternum and thoracic body wall.

Snowball J, Ambalavanan M, Cornett B, Lang R, Whitsett J, Sinner D.

Dev Biol. 2015 May 15;401(2):264-75. doi: 10.1016/j.ydbio.2015.02.014. Epub 2015 Feb 26.

4.

Golgi Phosphoprotein 3 Promotes Wls Recycling and Wnt Secretion in Glioma Progression.

Lu D, Zhang H, Fu J, Qi Y, Wang X, Wu S, Zhou X, Yu R.

Cell Physiol Biochem. 2018;47(6):2445-2457. doi: 10.1159/000491618. Epub 2018 Jul 10.

5.

Involvement of epithelial Wntless in the regulation of postnatal hair follicle morphogenesis.

Huang S, Zhu X, Tao Y, Sun Q, Wang L, Li B, He L, Guo X, Ma G.

Arch Dermatol Res. 2015 Nov;307(9):835-9. doi: 10.1007/s00403-015-1587-6. Epub 2015 Jul 9.

PMID:
26156041
6.

A Wntless-SEC12 complex on the ER membrane regulates early Wnt secretory vesicle assembly and mature ligand export.

Sun J, Yu S, Zhang X, Capac C, Aligbe O, Daudelin T, Bonder EM, Gao N.

J Cell Sci. 2017 Jul 1;130(13):2159-2171. doi: 10.1242/jcs.200634. Epub 2017 May 17.

7.

Identification of an endocytosis motif in an intracellular loop of Wntless protein, essential for its recycling and the control of Wnt protein signaling.

Gasnereau I, Herr P, Chia PZ, Basler K, Gleeson PA.

J Biol Chem. 2011 Dec 16;286(50):43324-33. doi: 10.1074/jbc.M111.307231. Epub 2011 Oct 25.

8.

Wntless (GPR177) expression correlates with poor prognosis in B-cell precursor acute lymphoblastic leukemia via Wnt signaling.

Chiou SS, Wang LT, Huang SB, Chai CY, Wang SN, Liao YM, Lin PC, Liu KY, Hsu SH.

Carcinogenesis. 2014 Oct;35(10):2357-64. doi: 10.1093/carcin/bgu166. Epub 2014 Aug 12.

PMID:
25115440
9.

Wntless Is Highly Expressed in Advanced-Stage Intrahepatic Cholangiocarcinoma.

Shi Y, Bai J, Guo S, Wang J.

Tohoku J Exp Med. 2018 Mar;244(3):195-199. doi: 10.1620/tjem.244.195.

10.

WIF1, a Wnt pathway inhibitor, regulates SKP2 and c-myc expression leading to G1 arrest and growth inhibition of human invasive urinary bladder cancer cells.

Tang Y, Simoneau AR, Liao WX, Yi G, Hope C, Liu F, Li S, Xie J, Holcombe RF, Jurnak FA, Mercola D, Hoang BH, Zi X.

Mol Cancer Ther. 2009 Feb;8(2):458-68. doi: 10.1158/1535-7163.MCT-08-0885. Epub 2009 Jan 27.

11.

Identifying novel members of the Wntless interactome through genetic and candidate gene approaches.

Petko J, Tranchina T, Patel G, Levenson R, Justice-Bitner S.

Brain Res Bull. 2018 Apr;138:96-105. doi: 10.1016/j.brainresbull.2017.07.004. Epub 2017 Jul 20.

12.

Wls promotes the proliferation of breast cancer cells via Wnt signaling.

Lu D, Li Y, Liu QR, Wu Q, Zhang H, Xie P, Wang Q.

Med Oncol. 2015 May;32(5):140. doi: 10.1007/s12032-015-0585-z. Epub 2015 Mar 24.

PMID:
25801232
13.

Wntless is required for peripheral lung differentiation and pulmonary vascular development.

Cornett B, Snowball J, Varisco BM, Lang R, Whitsett J, Sinner D.

Dev Biol. 2013 Jul 1;379(1):38-52. doi: 10.1016/j.ydbio.2013.03.010. Epub 2013 Mar 21.

14.

Epigenetic inactivation of Wnt inhibitory factor-1 plays an important role in bladder cancer through aberrant canonical Wnt/beta-catenin signaling pathway.

Urakami S, Shiina H, Enokida H, Kawakami T, Tokizane T, Ogishima T, Tanaka Y, Li LC, Ribeiro-Filho LA, Terashima M, Kikuno N, Adachi H, Yoneda T, Kishi H, Shigeno K, Konety BR, Igawa M, Dahiya R.

Clin Cancer Res. 2006 Jan 15;12(2):383-91.

15.

WNT5A inhibits hepatocyte proliferation and concludes β-catenin signaling in liver regeneration.

Yang J, Cusimano A, Monga JK, Preziosi ME, Pullara F, Calero G, Lang R, Yamaguchi TP, Nejak-Bowen KN, Monga SP.

Am J Pathol. 2015 Aug;185(8):2194-205. doi: 10.1016/j.ajpath.2015.04.021. Epub 2015 Jun 19.

16.

WLS inhibits melanoma cell proliferation through the β-catenin signalling pathway and induces spontaneous metastasis.

Yang PT, Anastas JN, Toroni RA, Shinohara MM, Goodson JM, Bosserhoff AK, Chien AJ, Moon RT.

EMBO Mol Med. 2012 Dec;4(12):1294-307. doi: 10.1002/emmm.201201486. Epub 2012 Nov 6.

17.

Distinct requirements for Wntless in habenular development.

Kuan YS, Roberson S, Akitake CM, Fortuno L, Gamse J, Moens C, Halpern ME.

Dev Biol. 2015 Oct 15;406(2):117-128. doi: 10.1016/j.ydbio.2015.06.006. Epub 2015 Jun 23.

18.

Wls is expressed in the epidermis and regulates embryonic hair follicle induction in mice.

Huang S, Zhu X, Liu Y, Tao Y, Feng G, He L, Guo X, Ma G.

PLoS One. 2012;7(9):e45904. doi: 10.1371/journal.pone.0045904. Epub 2012 Sep 24.

19.

Wnt signaling regulates homeostasis of the periodontal ligament.

Lim WH, Liu B, Cheng D, Williams BO, Mah SJ, Helms JA.

J Periodontal Res. 2014 Dec;49(6):751-9. doi: 10.1111/jre.12158. Epub 2014 Jan 11.

20.

Downregulation of Dickkopf-1 is responsible for high proliferation of breast cancer cells via losing control of Wnt/beta-catenin signaling.

Zhou XL, Qin XR, Zhang XD, Ye LH.

Acta Pharmacol Sin. 2010 Feb;31(2):202-10. doi: 10.1038/aps.2009.200.

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