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Items: 1 to 20 of 110

1.

PTEN regulates glioblastoma oncogenesis through chromatin-associated complexes of DAXX and histone H3.3.

Benitez JA, Ma J, D'Antonio M, Boyer A, Camargo MF, Zanca C, Kelly S, Khodadadi-Jamayran A, Jameson NM, Andersen M, Miletic H, Saberi S, Frazer KA, Cavenee WK, Furnari FB.

Nat Commun. 2017 May 12;8:15223. doi: 10.1038/ncomms15223. Erratum in: Nat Commun. 2018 May 25;9:16217.

2.

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma.

Schwartzentruber J, Korshunov A, Liu XY, Jones DT, Pfaff E, Jacob K, Sturm D, Fontebasso AM, Quang DA, Tönjes M, Hovestadt V, Albrecht S, Kool M, Nantel A, Konermann C, Lindroth A, Jäger N, Rausch T, Ryzhova M, Korbel JO, Hielscher T, Hauser P, Garami M, Klekner A, Bognar L, Ebinger M, Schuhmann MU, Scheurlen W, Pekrun A, Frühwald MC, Roggendorf W, Kramm C, Dürken M, Atkinson J, Lepage P, Montpetit A, Zakrzewska M, Zakrzewski K, Liberski PP, Dong Z, Siegel P, Kulozik AE, Zapatka M, Guha A, Malkin D, Felsberg J, Reifenberger G, von Deimling A, Ichimura K, Collins VP, Witt H, Milde T, Witt O, Zhang C, Castelo-Branco P, Lichter P, Faury D, Tabori U, Plass C, Majewski J, Pfister SM, Jabado N.

Nature. 2012 Jan 29;482(7384):226-31. doi: 10.1038/nature10833. Erratum in: Nature. 2012 Apr 5;484(7392):130.

PMID:
22286061
3.

H3.Y discriminates between HIRA and DAXX chaperone complexes and reveals unexpected insights into human DAXX-H3.3-H4 binding and deposition requirements.

Zink LM, Delbarre E, Eberl HC, Keilhauer EC, Bönisch C, Pünzeler S, Bartkuhn M, Collas P, Mann M, Hake SB.

Nucleic Acids Res. 2017 Jun 2;45(10):5691-5706. doi: 10.1093/nar/gkx131.

4.

The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3.

Drané P, Ouararhni K, Depaux A, Shuaib M, Hamiche A.

Genes Dev. 2010 Jun 15;24(12):1253-65. doi: 10.1101/gad.566910. Epub 2010 May 26.

5.

Tumor suppressor functions of DAXX through histone H3.3/H3K9me3 pathway in pancreatic NETs.

Ueda H, Akiyama Y, Shimada S, Mogushi K, Serizawa M, Matsumura S, Mitsunori Y, Aihara A, Ban D, Ochiai T, Kudo A, Tanabe M, Tanaka S.

Endocr Relat Cancer. 2018 Jun;25(6):619-631. doi: 10.1530/ERC-17-0328. Epub 2018 Mar 29.

PMID:
29599123
6.

Structural and mechanistic insights into ATRX-dependent and -independent functions of the histone chaperone DAXX.

Hoelper D, Huang H, Jain AY, Patel DJ, Lewis PW.

Nat Commun. 2017 Oct 30;8(1):1193. doi: 10.1038/s41467-017-01206-y.

7.

CENP-B protects centromere chromatin integrity by facilitating histone deposition via the H3.3-specific chaperone Daxx.

Morozov VM, Giovinazzi S, Ishov AM.

Epigenetics Chromatin. 2017 Dec 22;10(1):63. doi: 10.1186/s13072-017-0164-y.

8.

Viral reprogramming of the Daxx histone H3.3 chaperone during early Epstein-Barr virus infection.

Tsai K, Chan L, Gibeault R, Conn K, Dheekollu J, Domsic J, Marmorstein R, Schang LM, Lieberman PM.

J Virol. 2014 Dec;88(24):14350-63. doi: 10.1128/JVI.01895-14. Epub 2014 Oct 1.

9.

A novel PTEN/mutant p53/c-Myc/Bcl-XL axis mediates context-dependent oncogenic effects of PTEN with implications for cancer prognosis and therapy.

Huang X, Zhang Y, Tang Y, Butler N, Kim J, Guessous F, Schiff D, Mandell J, Abounader R.

Neoplasia. 2013 Aug;15(8):952-65.

10.

PTEN interacts with histone H1 and controls chromatin condensation.

Chen ZH, Zhu M, Yang J, Liang H, He J, He S, Wang P, Kang X, McNutt MA, Yin Y, Shen WH.

Cell Rep. 2014 Sep 25;8(6):2003-2014. doi: 10.1016/j.celrep.2014.08.008. Epub 2014 Sep 4.

11.

Control of human adenovirus type 5 gene expression by cellular Daxx/ATRX chromatin-associated complexes.

Schreiner S, Bürck C, Glass M, Groitl P, Wimmer P, Kinkley S, Mund A, Everett RD, Dobner T.

Nucleic Acids Res. 2013 Apr 1;41(6):3532-50. doi: 10.1093/nar/gkt064. Epub 2013 Feb 8.

12.
13.

Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres.

Lewis PW, Elsaesser SJ, Noh KM, Stadler SC, Allis CD.

Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14075-80. doi: 10.1073/pnas.1008850107. Epub 2010 Jul 22.

14.

DAXX-dependent supply of soluble (H3.3-H4) dimers to PML bodies pending deposition into chromatin.

Delbarre E, Ivanauskiene K, Küntziger T, Collas P.

Genome Res. 2013 Mar;23(3):440-51. doi: 10.1101/gr.142703.112. Epub 2012 Dec 5.

15.

Single-cell analysis of Daxx and ATRX-dependent transcriptional repression.

Newhart A, Rafalska-Metcalf IU, Yang T, Negorev DG, Janicki SM.

J Cell Sci. 2012 Nov 15;125(Pt 22):5489-501. doi: 10.1242/jcs.110148. Epub 2012 Sep 12.

16.

The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network.

Song MS, Salmena L, Carracedo A, Egia A, Lo-Coco F, Teruya-Feldstein J, Pandolfi PP.

Nature. 2008 Oct 9;455(7214):813-7. doi: 10.1038/nature07290. Epub 2008 Aug 20.

17.

Phosphatase and tensin homolog reconstruction and vascular endothelial growth factor knockdown synergistically inhibit the growth of glioblastoma.

Chen H, Shen X, Guo C, Zhu H, Zhou L, Zhu Y, Wang H, Zheng Y, Huang L.

Cancer Biother Radiopharm. 2010 Dec;25(6):713-21. doi: 10.1089/cbr.2010.0821.

PMID:
21204766
18.

Mislocalization of the centromeric histone variant CenH3/CENP-A in human cells depends on the chaperone DAXX.

Lacoste N, Woolfe A, Tachiwana H, Garea AV, Barth T, Cantaloube S, Kurumizaka H, Imhof A, Almouzni G.

Mol Cell. 2014 Feb 20;53(4):631-44. doi: 10.1016/j.molcel.2014.01.018. Epub 2014 Feb 13.

19.

DAXX envelops a histone H3.3-H4 dimer for H3.3-specific recognition.

Elsässer SJ, Huang H, Lewis PW, Chin JW, Allis CD, Patel DJ.

Nature. 2012 Nov 22;491(7425):560-5. doi: 10.1038/nature11608. Epub 2012 Oct 17.

20.

New players in heterochromatin silencing: histone variant H3.3 and the ATRX/DAXX chaperone.

Voon HP, Wong LH.

Nucleic Acids Res. 2016 Feb 29;44(4):1496-501. doi: 10.1093/nar/gkw012. Epub 2016 Jan 14. Review.

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