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Items: 1 to 20 of 100

1.

Probing the Effects of Gating on the Ion Occupancy of the K+ Channel Selectivity Filter Using Two-Dimensional Infrared Spectroscopy.

Kratochvil HT, Maj M, Matulef K, Annen AW, Ostmeyer J, Perozo E, Roux B, Valiyaveetil FI, Zanni MT.

J Am Chem Soc. 2017 Jul 5;139(26):8837-8845. doi: 10.1021/jacs.7b01594. Epub 2017 May 12.

2.

Ion-binding properties of a K+ channel selectivity filter in different conformations.

Liu S, Focke PJ, Matulef K, Bian X, Moënne-Loccoz P, Valiyaveetil FI, Lockless SW.

Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):15096-100. doi: 10.1073/pnas.1510526112. Epub 2015 Nov 23.

3.

Rapid constriction of the selectivity filter underlies C-type inactivation in the KcsA potassium channel.

Li J, Ostmeyer J, Cuello LG, Perozo E, Roux B.

J Gen Physiol. 2018 Aug 2. pii: jgp.201812082. doi: 10.1085/jgp.201812082. [Epub ahead of print]

PMID:
30072373
4.

A gate in the selectivity filter of potassium channels.

Bernèche S, Roux B.

Structure. 2005 Apr;13(4):591-600.

5.

Thermodynamic coupling between activation and inactivation gating in potassium channels revealed by free energy molecular dynamics simulations.

Pan AC, Cuello LG, Perozo E, Roux B.

J Gen Physiol. 2011 Dec;138(6):571-80. doi: 10.1085/jgp.201110670.

6.

K channel gating by an affinity-switching selectivity filter.

VanDongen AM.

Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):3248-52. Epub 2004 Feb 19.

7.

Detection of the opening of the bundle crossing in KcsA with fluorescence lifetime spectroscopy reveals the existence of two gates for ion conduction.

Blunck R, Cordero-Morales JF, Cuello LG, Perozo E, Bezanilla F.

J Gen Physiol. 2006 Nov;128(5):569-81. Epub 2006 Oct 16.

8.

Evidence for a deep pore activation gate in small conductance Ca2+-activated K+ channels.

Bruening-Wright A, Lee WS, Adelman JP, Maylie J.

J Gen Physiol. 2007 Dec;130(6):601-10. Epub 2007 Nov 12.

9.

Semisynthetic K+ channels show that the constricted conformation of the selectivity filter is not the C-type inactivated state.

Devaraneni PK, Komarov AG, Costantino CA, Devereaux JJ, Matulef K, Valiyaveetil FI.

Proc Natl Acad Sci U S A. 2013 Sep 24;110(39):15698-703. doi: 10.1073/pnas.1308699110. Epub 2013 Sep 9.

10.

Conformational changes in the selectivity filter of the open-state KcsA channel: an energy minimization study.

Miloshevsky GV, Jordan PC.

Biophys J. 2008 Oct;95(7):3239-51. doi: 10.1529/biophysj.108.136556. Epub 2008 Jul 11.

11.

Probing the energy landscape of activation gating of the bacterial potassium channel KcsA.

Linder T, de Groot BL, Stary-Weinzinger A.

PLoS Comput Biol. 2013;9(5):e1003058. doi: 10.1371/journal.pcbi.1003058. Epub 2013 May 2.

12.

Instantaneous ion configurations in the K+ ion channel selectivity filter revealed by 2D IR spectroscopy.

Kratochvil HT, Carr JK, Matulef K, Annen AW, Li H, Maj M, Ostmeyer J, Serrano AL, Raghuraman H, Moran SD, Skinner JL, Perozo E, Roux B, Valiyaveetil FI, Zanni MT.

Science. 2016 Sep 2;353(6303):1040-1044.

13.

Structural mechanism of C-type inactivation in K(+) channels.

Cuello LG, Jogini V, Cortes DM, Perozo E.

Nature. 2010 Jul 8;466(7303):203-8. doi: 10.1038/nature09153.

14.

The voltage-dependent gate in MthK potassium channels is located at the selectivity filter.

Posson DJ, McCoy JG, Nimigean CM.

Nat Struct Mol Biol. 2013 Feb;20(2):159-66. doi: 10.1038/nsmb.2473. Epub 2012 Dec 23.

15.

Structural and functional consequences of an amide-to-ester substitution in the selectivity filter of a potassium channel.

Valiyaveetil FI, Sekedat M, MacKinnon R, Muir TW.

J Am Chem Soc. 2006 Sep 6;128(35):11591-9.

16.

Selectivity filter gating in large-conductance Ca(2+)-activated K+ channels.

Thompson J, Begenisich T.

J Gen Physiol. 2012 Mar;139(3):235-44. doi: 10.1085/jgp.201110748.

17.

Structural basis for the coupling between activation and inactivation gates in K(+) channels.

Cuello LG, Jogini V, Cortes DM, Pan AC, Gagnon DG, Dalmas O, Cordero-Morales JF, Chakrapani S, Roux B, Perozo E.

Nature. 2010 Jul 8;466(7303):272-5. doi: 10.1038/nature09136.

18.

Role of protein dynamics in ion selectivity and allosteric coupling in the NaK channel.

Brettmann JB, Urusova D, Tonelli M, Silva JR, Henzler-Wildman KA.

Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):15366-71. doi: 10.1073/pnas.1515965112. Epub 2015 Nov 30.

19.

Localization of the activation gate for small conductance Ca2+-activated K+ channels.

Bruening-Wright A, Schumacher MA, Adelman JP, Maylie J.

J Neurosci. 2002 Aug 1;22(15):6499-506.

20.

Quantum mechanical calculations of charge effects on gating the KcsA channel.

Kariev AM, Znamenskiy VS, Green ME.

Biochim Biophys Acta. 2007 May;1768(5):1218-29. Epub 2007 Feb 6.

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