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Items: 1 to 20 of 113

1.

Heterologous Production and Yield Improvement of Epothilones in Burkholderiales Strain DSM 7029.

Bian X, Tang B, Yu Y, Tu Q, Gross F, Wang H, Li A, Fu J, Shen Y, Li YZ, Stewart AF, Zhao G, Ding X, Müller R, Zhang Y.

ACS Chem Biol. 2017 Jul 21;12(7):1805-1812. doi: 10.1021/acschembio.7b00097. Epub 2017 May 18.

PMID:
28467833
2.

Myxobacteria--'microbial factories' for the production of bioactive secondary metabolites.

Wenzel SC, Müller R.

Mol Biosyst. 2009 Jun;5(6):567-74. doi: 10.1039/b901287g. Epub 2009 Apr 23. Review.

PMID:
19462013
3.

Modular construction of a functional artificial epothilone polyketide pathway.

Osswald C, Zipf G, Schmidt G, Maier J, Bernauer HS, Müller R, Wenzel SC.

ACS Synth Biol. 2014 Oct 17;3(10):759-72. doi: 10.1021/sb300080t. Epub 2012 Nov 5.

PMID:
23654254
4.

A new approach for improving epothilone B yield in Sorangium cellulosum by the introduction of vgb epoF genes.

Ye W, Zhang W, Chen Y, Li H, Li S, Pan Q, Tan G, Liu T.

J Ind Microbiol Biotechnol. 2016 May;43(5):641-50. doi: 10.1007/s10295-016-1735-9. Epub 2016 Jan 23.

PMID:
26803504
5.

Heterologous production of epothilones B and D in Streptomyces venezuelae.

Park SR, Park JW, Jung WS, Han AR, Ban YH, Kim EJ, Sohng JK, Sim SJ, Yoon YJ.

Appl Microbiol Biotechnol. 2008 Nov;81(1):109-17. doi: 10.1007/s00253-008-1674-0. Epub 2008 Sep 4.

PMID:
18769916
6.

Co-cultivation of Sorangium cellulosum strains affects cellular growth and biosynthesis of secondary metabolite epothilones.

Li PF, Li SG, Li ZF, Zhao L, Wang T, Pan HW, Liu H, Wu ZH, Li YZ.

FEMS Microbiol Ecol. 2013 Aug;85(2):358-68. doi: 10.1111/1574-6941.12125. Epub 2013 Apr 18.

7.

Isolation of Sorangium cellulosum carrying epothilone gene clusters.

Hyun H, Chung J, Kim J, Lee JS, Kwon BM, Son KH, Cho K.

J Microbiol Biotechnol. 2008 Aug;18(8):1416-22.

8.

Heterologous expression of epothilone biosynthetic genes in Myxococcus xanthus.

Julien B, Shah S.

Antimicrob Agents Chemother. 2002 Sep;46(9):2772-8.

9.
10.

Mutation and a high-throughput screening method for improving the production of Epothilones of Sorangium.

Gong GL, Sun X, Liu XL, Hu W, Cao WR, Liu H, Liu WF, Li YZ.

J Ind Microbiol Biotechnol. 2007 Sep;34(9):615-23. Epub 2007 Jul 24.

PMID:
17647035
11.

Isolation and characterisation of the epothilone gene cluster with flanks from high alkalotolerant strain Sorangium cellulosum (So0157-2).

Li ZF, Zhu LP, Gu JY, Singh RP, Li YZ.

World J Microbiol Biotechnol. 2017 Jul;33(7):137. doi: 10.1007/s11274-017-2301-y. Epub 2017 Jun 5.

PMID:
28585173
12.

[The PKS/NRPS hetero-gene cluster of epothilones].

Li ZF, Nguimbi E, Li YZ, Liu WF.

Sheng Wu Gong Cheng Xue Bao. 2003 Sep;19(5):511-5. Review. Chinese.

PMID:
15969075
13.

The biosynthetic gene cluster for the microtubule-stabilizing agents epothilones A and B from Sorangium cellulosum So ce90.

Molnár I, Schupp T, Ono M, Zirkle R, Milnamow M, Nowak-Thompson B, Engel N, Toupet C, Stratmann A, Cyr DD, Gorlach J, Mayo JM, Hu A, Goff S, Schmid J, Ligon JM.

Chem Biol. 2000 Feb;7(2):97-109.

14.
15.

Heterologous production of epothilone C and D in Escherichia coli.

Mutka SC, Carney JR, Liu Y, Kennedy J.

Biochemistry. 2006 Jan 31;45(4):1321-30.

PMID:
16430229
16.

Production of the tubulin destabilizer disorazol in Sorangium cellulosum: biosynthetic machinery and regulatory genes.

Kopp M, Irschik H, Pradella S, Müller R.

Chembiochem. 2005 Jul;6(7):1277-86.

PMID:
15892181
17.

A bacterial negative transcription regulator binding on an inverted repeat in the promoter for epothilone biosynthesis.

Yue XJ, Cui XW, Zhang Z, Peng R, Zhang P, Li ZF, Li YZ.

Microb Cell Fact. 2017 May 23;16(1):92. doi: 10.1186/s12934-017-0706-9.

18.

Five new epothilone metabolites from Sorangium cellulosum strain So0157-2.

Wang J, Zhang H, Ying L, Wang C, Jiang N, Zhou Y, Wang H, Bai H.

J Antibiot (Tokyo). 2009 Sep;62(9):483-7. doi: 10.1038/ja.2009.55. Epub 2009 Jul 3.

PMID:
19575038
19.

Cloning and heterologous expression of the epothilone gene cluster.

Tang L, Shah S, Chung L, Carney J, Katz L, Khosla C, Julien B.

Science. 2000 Jan 28;287(5453):640-2.

20.

Glycosylation and production characteristics of epothilones in alkali-tolerant Sorangium cellulosum strain So0157-2.

Zhao L, Li PF, Lu CH, Li SG, Shen YM, Li YZ.

J Microbiol. 2010 Aug;48(4):438-44. doi: 10.1007/s12275-010-0048-3. Epub 2010 Aug 20.

PMID:
20799084

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