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Exploring the Predictive Ability of Dysfunctional High-Density Lipoprotein for Adverse Outcomes in Emergency Department Patients with Sepsis: A Preliminary Investigation.

Guirgis FW, Dodani S, Moldawer L, Leeuwenburgh C, Bowman J, Kalynych C, Jones AE, Reddy ST, Moore FA.

Shock. 2017 Nov;48(5):539-544. doi: 10.1097/SHK.0000000000000887.


HDL inflammatory index correlates with and predicts severity of organ failure in patients with sepsis and septic shock.

Guirgis FW, Dodani S, Leeuwenburgh C, Moldawer L, Bowman J, Kalynych C, Grijalva V, Reddy ST, Jones AE, Moore FA.

PLoS One. 2018 Sep 14;13(9):e0203813. doi: 10.1371/journal.pone.0203813. eCollection 2018.


Anti-oxidative and cholesterol efflux capacities of high-density lipoprotein are reduced in ischaemic cardiomyopathy.

Patel PJ, Khera AV, Wilensky RL, Rader DJ.

Eur J Heart Fail. 2013 Nov;15(11):1215-9. doi: 10.1093/eurjhf/hft084. Epub 2013 May 24.


Decreased high-density lipoprotein cholesterol level is an early prognostic marker for organ dysfunction and death in patients with suspected sepsis.

Cirstea M, Walley KR, Russell JA, Brunham LR, Genga KR, Boyd JH.

J Crit Care. 2017 Apr;38:289-294. doi: 10.1016/j.jcrc.2016.11.041. Epub 2016 Dec 7.


HDL Cholesterol Efflux is Impaired in Older Patients with Early Sepsis: A Subanalysis of a Prospective Pilot Study.

Guirgis FW, Leeuwenburgh C, Grijalva V, Bowman J, Kalynych C, Moldawer L, Moore FA, Reddy ST.

Shock. 2018 Jul;50(1):66-70. doi: 10.1097/SHK.0000000000001030.


Changes in HDL-associated apolipoproteins relate to mortality in human sepsis and correlate to monocyte and platelet activation.

Barlage S, Gnewuch C, Liebisch G, Wolf Z, Audebert FX, Glück T, Fröhlich D, Krämer BK, Rothe G, Schmitz G.

Intensive Care Med. 2009 Nov;35(11):1877-85. doi: 10.1007/s00134-009-1609-y. Epub 2009 Aug 8.


Lipoprotein metabolism in patients with severe sepsis.

van Leeuwen HJ, Heezius EC, Dallinga GM, van Strijp JA, Verhoef J, van Kessel KP.

Crit Care Med. 2003 May;31(5):1359-66.


The anti-oxidative capacity of high-density lipoprotein is reduced in acute coronary syndrome but not in stable coronary artery disease.

Patel PJ, Khera AV, Jafri K, Wilensky RL, Rader DJ.

J Am Coll Cardiol. 2011 Nov 8;58(20):2068-75. doi: 10.1016/j.jacc.2011.08.030.


Antioxidant properties of high-density lipoproteins are impaired in women with polycystic ovary syndrome.

Zhang J, Zhang Y, Liu H, Bai H, Wang Y, Jiang C, Fan P.

Fertil Steril. 2015 May;103(5):1346-54. doi: 10.1016/j.fertnstert.2015.02.024. Epub 2015 Mar 23.


Low serum level of high-density lipoprotein cholesterol is a poor prognostic factor for severe sepsis.

Chien JY, Jerng JS, Yu CJ, Yang PC.

Crit Care Med. 2005 Aug;33(8):1688-93. Erratum in: Crit Care Med. 2005 Nov;33(11):2727.


Heart failure is associated with impaired anti-inflammatory and antioxidant properties of high-density lipoproteins.

Kim JB, Hama S, Hough G, Navab M, Fogelman AM, Maclellan WR, Horwich TB, Fonarow GC.

Am J Cardiol. 2013 Dec 1;112(11):1770-7. doi: 10.1016/j.amjcard.2013.07.045. Epub 2013 Sep 16.


The dual nature of HDL: Anti-Inflammatory and pro-Inflammatory.

Namiri-Kalantari R, Gao F, Chattopadhyay A, Wheeler AA, Navab KD, Farias-Eisner R, Reddy ST.

Biofactors. 2015 May 6;41(3):153-9. doi: 10.1002/biof.1205. Epub 2015 Jun 13. Review.


Impact of cigarette smoking cessation on high-density lipoprotein functionality.

Takata K, Imaizumi S, Kawachi E, Suematsu Y, Shimizu T, Abe S, Matsuo Y, Tsukahara H, Noda K, Yahiro E, Zhang B, Uehara Y, Miura S, Saku K.

Circ J. 2014;78(12):2955-62. Epub 2014 Oct 16.


Serum lipid profile, cytokine production, and clinical outcome in patients with severe sepsis.

Lekkou A, Mouzaki A, Siagris D, Ravani I, Gogos CA.

J Crit Care. 2014 Oct;29(5):723-7. doi: 10.1016/j.jcrc.2014.04.018. Epub 2014 Apr 24.


Cholesterol Efflux Capacity, High-Density Lipoprotein Particle Number, and Incident Cardiovascular Events: An Analysis From the JUPITER Trial (Justification for the Use of Statins in Prevention: An Intervention Trial Evaluating Rosuvastatin).

Khera AV, Demler OV, Adelman SJ, Collins HL, Glynn RJ, Ridker PM, Rader DJ, Mora S.

Circulation. 2017 Jun 20;135(25):2494-2504. doi: 10.1161/CIRCULATIONAHA.116.025678. Epub 2017 Apr 27.


CC-Chemokine Ligand 2 (CCL2) Suppresses High Density Lipoprotein (HDL) Internalization and Cholesterol Efflux via CC-Chemokine Receptor 2 (CCR2) Induction and p42/44 Mitogen-activated Protein Kinase (MAPK) Activation in Human Endothelial Cells.

Sun RL, Huang CX, Bao JL, Jiang JY, Zhang B, Zhou SX, Cai WB, Wang H, Wang JF, Zhang YL.

J Biol Chem. 2016 Sep 9;291(37):19532-44. doi: 10.1074/jbc.M116.714279. Epub 2016 Jul 25.


A prospective, multicenter derivation of a biomarker panel to assess risk of organ dysfunction, shock, and death in emergency department patients with suspected sepsis.

Shapiro NI, Trzeciak S, Hollander JE, Birkhahn R, Otero R, Osborn TM, Moretti E, Nguyen HB, Gunnerson KJ, Milzman D, Gaieski DF, Goyal M, Cairns CB, Ngo L, Rivers EP.

Crit Care Med. 2009 Jan;37(1):96-104. doi: 10.1097/CCM.0b013e318192fd9d.


[Changes in plasma cholesterol level and risk factors of death in patients with sepsis].

Bai J, Lin J, Zhuang H, Guo D, Yang X, Duan M.

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2016 Feb;28(2):164-8. doi: 10.3760/cma.j.issn.2095-4352.2016.02.015. Chinese.


High levels of oxidized fatty acids in HDL are associated with impaired HDL function in patients with active rheumatoid arthritis.

Charles-Schoeman C, Meriwether D, Lee YY, Shahbazian A, Reddy ST.

Clin Rheumatol. 2018 Mar;37(3):615-622. doi: 10.1007/s10067-017-3896-y. Epub 2017 Nov 11.


Impaired antioxidant HDL function is associated with premature myocardial infarction.

Distelmaier K, Wiesbauer F, Blessberger H, Oravec S, Schrutka L, Binder C, Dostal E, Schillinger M, Wojta J, Lang IM, Maurer G, Huber K, Goliasch G.

Eur J Clin Invest. 2015 Jul;45(7):731-8. doi: 10.1111/eci.12466. Epub 2015 Jun 19.


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