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28411222,26038759,23611308,28263995,20615927,23030501,19010828,31862721,26213381,16377667,25454214,27241369,25888077,21163629,22736609,25614358,27999440,28438824,14576095,21816945,24252780,31132246,16437348,26713750,28194715,21586784,22591918,25041576,33835090,27339028,23699065,33049327,16450834,22228044,30832446,19805560,32792334,26797908,16556639,20967790,30078425,32338055,25549879,25784524,26812821,29175074,28696232,18814909,31653277,12886054,25540773,20572203,20586169,33785630,15972312,8519470,19528175,22167157,22191529,17188446,19640858,25001104,31456169,21466040,24389080,20187117,29227161,30329212,23622723,29776929,25264073,25560011,18676219,26763935,25315757,22901790,27896496,19143172,28062458,28461319,24436195,25713785,28559263,35762769,19451302,21784640,22926575,33277548,33492206,22854340,20685626,23010032,26905757,16627606,28720732,35796649,32801173,19749058,29168130,31642039,25465522,31731408,27930835,12543535,29536668,29720089,18924086,34446785,27185376,30338533,34792719,31772059,18039822,33044989,27227309,25267673,21761219,29901811,31471074,29885758,29488195,17374894,34634935,22919653,17172522,31088602,20709333,15070512,25034276,34170218,8404917,17692209,21844319,24390796,19651903,31847306,26896504,29460278,29096369,25242939,32542979,29203484,11926741,25203125,18201873,28610835,11764727,18725436,30057355,31761480,24599648,31509623,30099281,32122902,29712650,24111986,28893777,30022542,17967908,30117414,28744944,1490921,19451280,29611650,25368206,9756787,35300379,21415203,21255298,23840636,20963728,27729510,30247876,30760047,29160896,19856267,20595208,7928823,29288553,22623343,25182634,32640045,31389671,29369234,36851674,30890745,21135178,33225755,31357240,22964248,20890879,22664505,32988818,30698031,9597250,23688391,30315918,20485435,30111629,26297246,35861539,11733463,22435667,29737589,31339915,20719763,7957277,8555579,32549248,29305985,33882647,30816474,30370437,29159979,30406042,21393458,20404119,12793569,18924098,33284019,19856266,26461083,27394715,35107361,28869803,19564370,30850614,31863153,24737057,23273885,24696518,27836851,25025650,21402153,30172935,26272750,30503373,34553684,32469943,28826250,25749322,24492358,32144756,12628549,29795120,29293434,31454398,29334249,27999062,27033568,34536464,32498595,30628885,29883434,11385323,19778348,28252025,19856274,35019768,29317687,34443349,28664201,28358851,28066954,32464355,30818374,27351824,16353126,31152793,19365686,26303796,10405419,25079512,33433854,30965089,22229614,16056025,36453944,14576121,33682623,31066863,17645225,25658642,36325465,27222468,30654101,30771288,32725897,26272283,36306163,30786799,21630583,31871084,18025674,30885396,31681633,17708451,9559803,31470047,27498831,28710559,27214405,33287389,33353409,28434696,19860905,28327271,30954574,29158277,36675063,22682712,28598304,24660614,11157901,25189861,23970550,11166241,25053799,30508627,36314923,1425733,22958527,19429756,10459809,26784529,12760879,30867835,21816417,29924414,32267888,29744925,31624909,29687885,22434724,36076252,9533456,30126174,25288093,28782178,20521936,30735113,8769462,33611618,36982293,12969283,10415452,25686940,30010876,23746961,15047551,24228850,2206204,36481431,29734657,36350889,31636066,34148884,28396543,27144276,32992766,31292342,9848447,27434592,28475673,28612299,20002576,30031161,27496452,15626979,23220967,11891733,28378343,33988969,22733073,22815921,25036054,30954635,20443892,28946655,25807791,33413448,29251486,32663508,29969476,34704807,21220484,28616631,24411017,28873268,19609257,30955967,23114780,34838856,31972270,30334871,23056272,28387349,30465823,31705015,31549575,27643487,32068136,33619696,26489040,28212143,28471351,24164269,30119595,27129223,32709721,28435269,30345922,31419978,36735239,28922066,31630525,21508677,23490006,20191335,30665698,9987191,28507110,35196793,27503656,23519963,27259704,35852317,28885721,27604263,19047636,30785206,22231397,33136443,30207891,32102851,23917310,21800262,36232391,35816884,18832327,31451499,26919404,23921230,30142222,27458233,29063212,31313901,21558434,36510276,31605761,29881840,36916557,31251598,30747987,21857375,25375335,33375201,33092628,22802343,30426000,36498843,31420962,28834707,21845045,14638511,9089861,30091042,35746811,30519018,27091926,31170971,33807362,30172300,28939440,33097681,31954031,24958708,21887652,33057728,36449895,34253065,28420544,24735724,31127270,2600003,29426873,16353125,33664312,29603341,19389780,27872074,27517714,27068096,11398399,36012520,7915751,7983497,22753376,28868925,11064246,29846772,36286507,32586125,27989223,28289031,20528930,31421782,2765629,27260167,11444767,27288863,23450111,34871207,22828414,28473710,37057584,17918127,32013221,27578990,26119274,21859333,33255054,3972755,18481220,33468484,23208606,18453278,33526569,28504348,30790318,28245229,29923129,23390899,14616685,22242149,29654371,11245318,35163738,30760667,26501916,31812797,20679509,32449679,11932199,15609240,33846401,30477343,31630921,34194840,35414488,9158580,32916327,26369955,31427303,23057709,33230594,25155589,31486108,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Page 1

Effect of Antimicrobial and Physical Treatments on Growth of Multispecies Staphylococcal Biofilms.

Stewart EJ, Payne DE, Ma TM, VanEpps JS, Boles BR, Younger JG, Solomon MJ. Stewart EJ, et al. Appl Environ Microbiol. 2017 May 31;83(12):e03483-16. doi: 10.1128/AEM.03483-16. Print 2017 Jun 15. Appl Environ Microbiol. 2017. PMID: 28411222 Free PMC article.

Antibacterial and anti-biofilm activities of thiazolidione derivatives against clinical staphylococcus strains.

Liu H, Zhao Y, Zhao D, Gong T, Wu Y, Han H, Xu T, Peschel A, Han S, Qu D. Liu H, et al. Emerg Microbes Infect. 2015 Jan;4(1):e1. doi: 10.1038/emi.2015.1. Epub 2015 Jan 7. Emerg Microbes Infect. 2015. PMID: 26038759 Free PMC article.

In vitro susceptibility to antibiotics of staphylococci in biofilms isolated from orthopaedic infections.

Molina-Manso D, del Prado G, Ortiz-Pérez A, Manrubia-Cobo M, Gómez-Barrena E, Cordero-Ampuero J, Esteban J. Molina-Manso D, et al. Int J Antimicrob Agents. 2013 Jun;41(6):521-3. doi: 10.1016/j.ijantimicag.2013.02.018. Epub 2013 Apr 20. Int J Antimicrob Agents. 2013. PMID: 23611308

Metabolic activity, urease production, antibiotic resistance and virulence in dual species biofilms of Staphylococcus epidermidis and Staphylococcus aureus.

Vandecandelaere I, Van Nieuwerburgh F, Deforce D, Coenye T. Vandecandelaere I, et al. PLoS One. 2017 Mar 6;12(3):e0172700. doi: 10.1371/journal.pone.0172700. eCollection 2017. PLoS One. 2017. PMID: 28263995 Free PMC article.

Penetration of antibiotics through Staphylococcus aureus and Staphylococcus epidermidis biofilms.

Singh R, Ray P, Das A, Sharma M. Singh R, et al. J Antimicrob Chemother. 2010 Sep;65(9):1955-8. doi: 10.1093/jac/dkq257. Epub 2010 Jul 8. J Antimicrob Chemother. 2010. PMID: 20615927

Enhanced activity of carvacrol against biofilm of Staphylococcus aureus and Staphylococcus epidermidis in an acidic environment.

Nostro A, Cellini L, Zimbalatti V, Blanco AR, Marino A, Pizzimenti F, Di Giulio M, Bisignano G. Nostro A, et al. APMIS. 2012 Dec;120(12):967-73. doi: 10.1111/j.1600-0463.2012.02928.x. Epub 2012 Jul 5. APMIS. 2012. PMID: 23030501

High in vitro antimicrobial activity of synthetic antimicrobial peptidomimetics against staphylococcal biofilms.

Flemming K, Klingenberg C, Cavanagh JP, Sletteng M, Stensen W, Svendsen JS, Flaegstad T. Flemming K, et al. J Antimicrob Chemother. 2009 Jan;63(1):136-45. doi: 10.1093/jac/dkn464. Epub 2008 Nov 14. J Antimicrob Chemother. 2009. PMID: 19010828

Small Molecules Produced by Commensal Staphylococcus epidermidis Disrupt Formation of Biofilms by Staphylococcus aureus.

Glatthardt T, Campos JCM, Chamon RC, de Sá Coimbra TF, Rocha GA, de Melo MAF, Parente TE, Lobo LA, Antunes LCM, Dos Santos KRN, Ferreira RBR. Glatthardt T, et al. Appl Environ Microbiol. 2020 Feb 18;86(5):e02539-19. doi: 10.1128/AEM.02539-19. Print 2020 Feb 18. Appl Environ Microbiol. 2020. PMID: 31862721 Free PMC article.

Potency and penetration of telavancin in staphylococcal biofilms.

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