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Items: 1 to 20 of 101

1.

LACTB is a tumour suppressor that modulates lipid metabolism and cell state.

Keckesova Z, Donaher JL, De Cock J, Freinkman E, Lingrell S, Bachovchin DA, Bierie B, Tischler V, Noske A, Okondo MC, Reinhardt F, Thiru P, Golub TR, Vance JE, Weinberg RA.

Nature. 2017 Mar 30;543(7647):681-686. doi: 10.1038/nature21408. Epub 2017 Mar 22.

2.

Quiescence-like Metabolism to Push Cancer Out of the Race.

Torrano V, Carracedo A.

Cell Metab. 2017 May 2;25(5):997-999. doi: 10.1016/j.cmet.2017.04.027.

3.

LACTB, a novel epigenetic silenced tumor suppressor, inhibits colorectal cancer progression by attenuating MDM2-mediated p53 ubiquitination and degradation.

Zeng K, Chen X, Hu X, Liu X, Xu T, Sun H, Pan Y, He B, Wang S.

Oncogene. 2018 Oct;37(41):5534-5551. doi: 10.1038/s41388-018-0352-7. Epub 2018 Jun 13.

PMID:
29899406
4.

Overexpression of LACTB, a Mitochondrial Protein That Inhibits Proliferation and Invasion in Glioma Cells.

Li HT, Dong DY, Liu Q, Xu YQ, Chen L.

Oncol Res. 2019 Mar 29;27(4):423-429. doi: 10.3727/096504017X15030178624579. Epub 2017 Aug 23.

PMID:
28835318
5.

LACTB-mediated tumour suppression by increased mitochondrial lipid metabolism.

Cucchi D, Mauro C.

Cell Death Differ. 2017 Jul;24(7):1137-1139. doi: 10.1038/cdd.2017.60. Epub 2017 May 5. No abstract available.

6.

LACTB is a filament-forming protein localized in mitochondria.

Polianskyte Z, Peitsaro N, Dapkunas A, Liobikas J, Soliymani R, Lalowski M, Speer O, Seitsonen J, Butcher S, Cereghetti GM, Linder MD, Merckel M, Thompson J, Eriksson O.

Proc Natl Acad Sci U S A. 2009 Nov 10;106(45):18960-5. doi: 10.1073/pnas.0906734106. Epub 2009 Oct 26.

7.

Lipid Homeostasis Is Maintained by Dual Targeting of the Mitochondrial PE Biosynthesis Enzyme to the ER.

Friedman JR, Kannan M, Toulmay A, Jan CH, Weissman JS, Prinz WA, Nunnari J.

Dev Cell. 2018 Jan 22;44(2):261-270.e6. doi: 10.1016/j.devcel.2017.11.023. Epub 2017 Dec 28.

9.

NAF-1 and mitoNEET are central to human breast cancer proliferation by maintaining mitochondrial homeostasis and promoting tumor growth.

Sohn YS, Tamir S, Song L, Michaeli D, Matouk I, Conlan AR, Harir Y, Holt SH, Shulaev V, Paddock ML, Hochberg A, Cabanchick IZ, Onuchic JN, Jennings PA, Nechushtai R, Mittler R.

Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):14676-81. doi: 10.1073/pnas.1313198110. Epub 2013 Aug 19.

10.

Loss of the novel mitochondrial protein FAM210B promotes metastasis via PDK4-dependent metabolic reprogramming.

Sun S, Liu J, Zhao M, Han Y, Chen P, Mo Q, Wang B, Chen G, Fang Y, Tian Y, Zhou J, Ma D, Gao Q, Wu P.

Cell Death Dis. 2017 Jun 8;8(6):e2870. doi: 10.1038/cddis.2017.273.

11.

[Over expression of hyperplasia suppressor gene inhibits the malignant phenotype of breast cancer cell].

Zhang Y, DU Q, Qiu XY, Tian XX, Fang WG.

Zhonghua Bing Li Xue Za Zhi. 2010 Apr;39(4):259-63. Chinese.

PMID:
20654126
12.

RASSF1A inhibits estrogen receptor alpha expression and estrogen-independent signalling: implications for breast cancer development.

Thaler S, Schmidt M, Schad A, Sleeman JP.

Oncogene. 2012 Nov 22;31(47):4912-22. doi: 10.1038/onc.2011.658. Epub 2012 Jan 23.

PMID:
22266866
13.

Ataxia telangiectasia mutated (ATM) inhibition transforms human mammary gland epithelial cells.

Mandriota SJ, Buser R, Lesne L, Stouder C, Favaudon V, Maechler P, Béna F, Clément V, Rüegg C, Montesano R, Sappino AP.

J Biol Chem. 2010 Apr 23;285(17):13092-106. doi: 10.1074/jbc.M109.078360. Epub 2010 Feb 22.

14.

Genistein modulates oxidative stress in breast cancer cell lines according to ERα/ERβ ratio: effects on mitochondrial functionality, sirtuins, uncoupling protein 2 and antioxidant enzymes.

Nadal-Serrano M, Pons DG, Sastre-Serra J, Blanquer-Rosselló Mdel M, Roca P, Oliver J.

Int J Biochem Cell Biol. 2013 Sep;45(9):2045-51. doi: 10.1016/j.biocel.2013.07.002. Epub 2013 Jul 17.

PMID:
23871935
15.

Breast cancer subtype dictates DNA methylation and ALDH1A3-mediated expression of tumor suppressor RARRES1.

Coyle KM, Murphy JP, Vidovic D, Vaghar-Kashani A, Dean CA, Sultan M, Clements D, Wallace M, Thomas ML, Hundert A, Giacomantonio CA, Helyer L, Gujar SA, Lee PW, Weaver IC, Marcato P.

Oncotarget. 2016 Jul 12;7(28):44096-44112. doi: 10.18632/oncotarget.9858.

16.

ZIC1 acts a tumor suppressor in breast cancer by targeting survivin.

Han W, Cao F, Gao XJ, Wang HB, Chen F, Cai SJ, Zhang C, Hu YW, Ma J, Gu X, Ding HZ.

Int J Oncol. 2018 Sep;53(3):937-948. doi: 10.3892/ijo.2018.4450. Epub 2018 Jun 21.

17.

miR-296/Scribble axis is deregulated in human breast cancer and miR-296 restoration reduces tumour growth in vivo.

Savi F, Forno I, Faversani A, Luciani A, Caldiera S, Gatti S, Foa P, Ricca D, Bulfamante G, Vaira V, Bosari S.

Clin Sci (Lond). 2014 Aug;127(4):233-42. doi: 10.1042/CS20130580.

PMID:
24527800
18.

Semaphorin-plexin signalling genes associated with human breast tumourigenesis.

Gabrovska PN, Smith RA, Tiang T, Weinstein SR, Haupt LM, Griffiths LR.

Gene. 2011 Dec 10;489(2):63-9. doi: 10.1016/j.gene.2011.08.024. Epub 2011 Sep 2.

PMID:
21925246
19.

Cardiolipin and mitochondrial phosphatidylethanolamine have overlapping functions in mitochondrial fusion in Saccharomyces cerevisiae.

Joshi AS, Thompson MN, Fei N, Hüttemann M, Greenberg ML.

J Biol Chem. 2012 May 18;287(21):17589-97. doi: 10.1074/jbc.M111.330167. Epub 2012 Mar 20.

20.

GRAMD4 mimics p53 and mediates the apoptotic function of p73 at mitochondria.

John K, Alla V, Meier C, Pützer BM.

Cell Death Differ. 2011 May;18(5):874-86. doi: 10.1038/cdd.2010.153. Epub 2010 Dec 3. Erratum in: Cell Death Differ. 2012 Mar;19(3):552.

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